Frédérique Le Roux
Frédérique Le Roux
@fredoleroux.bsky.social
What do I like? Wild things 😜 yet phages are my favorite!
506 followers360 following65 posts
Après la Coupe du monde de foot, place à la tournée du @cinqascience.bsky.social au café Chez Ernest ! Les conférences reprendront tous les mercredis à partir de 18 h (22 juillet-26 aout) : 🍻 30 minutes de présentation 💬 30 minutes de discussion autour d’un verre
Frédérique Le Roux reposted
Frédérique Le Roux reposted
Want to join us for Social Viruses in Vancouver this summer? One week to go until we start looking at applications (May 7th). To apply: socialviruses.zoology.ubc.ca #socialviruses #evosky #lovevirology #virosky
The Social Lives of Viruses is coming to Vancouver, Canada, from 4th-8th August 2026! This is a free meeting dedicated to all aspects of virus-virus interactions & evolution. To apply: socialviruses.zoology.ubc.ca @sociovirology.bsky.social #socialviruses #evosky #lovevirology #virosky
Frédérique Le Roux reposted
The Social Lives of Viruses is coming to Vancouver, Canada, from 4th-8th August 2026! This is a free meeting dedicated to all aspects of virus-virus interactions & evolution. To apply: socialviruses.zoology.ubc.ca @sociovirology.bsky.social #socialviruses #evosky #lovevirology #virosky
Frédérique Le Roux reposted
Excited to share our new paper out today in @science.org 🎉 We show that HGT via natural competence drives diversification of chromosomal integrons in V. cholerae 🤩 Below a 🧵 on key findings incl. background on natural competence in V. cholerae 1/ #microsky #phagesky www.science.org/doi/10.1126/...
>1000 lytic vibriophages sequenced. 4 years later… still there. Same genomes. Same vibes. Different story. When nothing changes—but everything does. Congrats to Jeff & Karine et al. and @epcrocha.bsky.social for the intellectual turbulence ;-) www.nature.com/articles/s41...
Many thanks to @erc.europa.eu @agencerecherche.bsky.social Université de Montréal, Fondation Courtois, CERC, FCI; @cnrs.fr @pasteur.fr and yes I still eat oysters...
Frédérique Le Roux reposted
Replying to @epcrocha.bsky.social
Finally, oysters serve as hotspots of horizontal gene transfer betw bacteria, mediated by mobile genetic elements. Which, considering the high density of bacteria in marine animals (rel. environment), could be quite general. Great work led by Jeff Liang, Karine Cahier. With @fredoleroux.bsky.social
Frédérique Le Roux reposted
Our ms on re-sampling 4 years apart vibrio phage in natural environments is now out with some improvements. First, clearer evidence of cryptic population dynamics between phage and vibrio, presumably because of genetic diversity. www.nature.com/articles/s41...
Frédérique Le Roux reposted
Latest from the lab! Between clinical S. aureus, most gene transfer mechanisms are blocked, yet lateral transduction remains highly efficient. Restriction modification-defective strains act as gateways for horizontal gene transfer, enabling DNA flow across populations. rdcu.be/fbNQK
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🦠💊 L’Institut @pasteur.fr vient de publier un communiqué de presse sur nos récents travaux, qui décrivent une nouvelle piste pour augmenter l’efficacité des antibiotiques. #Pasteurdon #Recherche #Science #AMR Merci à toutes celles et ceux qui ont contribué. 📘 English version coming soon!
Frédérique Le Roux reposted
Replying to @epcrocha.bsky.social
Many thanks to all those involved, including Jeffrey Liang, who stayed in our lab for several months, our own Charles Bernard and, of course, @fredoleroux.bsky.social and the usual suspects @agencerecherche.bsky.social @erc.europa.eu @cnrsbiologie.bsky.social @pasteur.fr @umontreal.ca etc
Frédérique Le Roux reposted
Two intensive sampling periods of oyster-associated vibrio and their phage, 4 years apart, and many surprises. Despite being washed by the Atlantic, wide tides, and vibrio (almost?) disappearing most of the year, we can find the exact same virulent phages 4 years later (down to 0 SNP)! preprint👇
Phages evolve fast, or do they? In oysters, some stay identical for years. With >1,200 phages & 600 Vibrio genomes, we reveal long-term stability and new mobile elements. Proud of this collaborative work across our teams (Roscoff-UdeM and @epcrocha.bsky.social www.biorxiv.org/cgi/content/...
Phages evolve fast, or do they? In oysters, some stay identical for years. With >1,200 phages & 600 Vibrio genomes, we reveal long-term stability and new mobile elements. Proud of this collaborative work across our teams (Roscoff-UdeM and @epcrocha.bsky.social www.biorxiv.org/cgi/content/...
Frédérique Le Roux reposted
Thrilled to share our two latest papers with the @tcostalab.bsky.social lab! In the first, we uncover a new mechanism of satellite transfer: cf-PICIs hijack tails from diverse phages to spread across species. @imperialcollegeldn.bsky.social www.cell.com/cell/fulltex...
Frédérique Le Roux reposted
Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization: Cell www.cell.com/cell/fulltex...
Frédérique Le Roux reposted
The ecology and evolution of microbial immune systems: a look on the wild vibrio side Phil. Trans. R. Soc. B by @fredoleroux.bsky.social royalsocietypublishing.org/doi/10.1098/...
Frédérique Le Roux reposted
The study involves our microbiologist @fredoleroux.bsky.social, whom we profiled in late 2023 as a new hire and Canada Excellence in Research Chair: nouvelles.umontreal.ca/en/article/2...
🧬 Bacteria fight both antibiotics and viruses with the same genetic tool: integrons! New study (Institut Pasteur, CNRS, Université Paris Cité & Montréal): ~10% of gene cassettes may defend against phages. 🛠️ One step closer to smarter therapies. 🔗 www.pasteur.fr/en/research-...
Frédérique Le Roux reposted
Frédérique Le Roux reposted
Frédérique Le Roux reposted
Replying to @bjesseshapiro.bsky.social
And I've written a few reviews on the subject over the years, but this one is pretty short, so why not start there ;) www.sciencedirect.com/science/arti...