Genetics Society of America

You told us connection matters, and at #Dros27, great conversations are just steps away (10 minutes max from the venue). Grab a meal at Reading Terminal Market, stroll to Philadelphia City Hall, or connect over coffee at local favorites. Philly locals—where should attendees go?

🪱 A study in #G3journal identified and validated the Hedgehog-like signaling molecule ptr-6 as a genetic suppressor of the FASN gene fasn-1 in #Celegans, revealing a previously unknown connection between fatty acid synthesis and Hedgehog-like signaling during embryonic development. 🔗 buff.ly/XOCHahj

🪰 Latest in #G3journal: A study in #Drosophila simulans suggests that paternal #mitochondrial DNA leakage is genetically controlled, offering new insight into its evolutionary significance and potential role in mitochondrial genome maintenance. 🔗 buff.ly/GNm5EW0

🫂 In #G3journal, David Curtis dives into @ukbiobank.ac.uk whole-genome sequence data from half a million participants to estimate relative mutation rates between transcribed and nontranscribed regions. 🔗 buff.ly/48lrVeb

🍄‍🟫 The #Fungal26 virtual collection is now available! Explore research presented at the 33rd Fungal Genetics Conference, published in #GENETICS and #G3Journal. Browse the collection: buff.ly/ohBGyJ8

📣 Calling all C. elegans researchers! @royalsocietypublishing.org has released a new Theo Murphy Meeting issue of Philosophical Transactions B: ProteostaSys: A Systems View of Proteostasis. All articles are FREE to access! 🔗: buff.ly/wqdvUNB

In #G3journal, Mitchell Feldmann and colleagues present lower-cost, scalable DNA tools that could make precision strawberry 🍓 #breeding more accessible, helping identify superior plants faster. 🔗 buff.ly/1PnSE4A

In #G3journal, Olumide Onabanjo & Co introduce #deeplearning as a genetic simulation model, showing how genetic trait architectures derived from these models, when sufficiently complex, capture complex interactions that preserve genetic variance. 🔗 buff.ly/1gf3aXm

🍄 🧬 A computational study published in #G3journal analyzes secretion signals across the fungal kingdom, identifying distinct populations of secreted proteins in diverse fungal species. 🔗 buff.ly/jBwiz5Q

Mark your calendars! Join GSA on November 12, 1–2:30 p.m. EST, for "Teaching with Purpose: Implementing the New Genetics Learning Outcomes" to explore updates to the Genetics Learning Framework and how to apply new learning outcomes to your curriculum. 🔗: buff.ly/fVyHaIK

What is an R01 grant? Explore what it takes to get a National Institutes of Health research grant in our latest blog series. Read the blogs now: buff.ly/2yyowws @springcyclone.bsky.social

🪱 New in #G3journal: A large-scale behavior characterization of sensitivity to the aversive odorant 1-octanol in wild strains gathered from around the globe is the first-ever study at scale that investigates how natural genetic variation shapes #Celegans olfactory behavior. 🔗 buff.ly/suEm15k

New in #G3jounral: A mutant analysis in #Ecoli reveals that bacterial helicase function during severe transcription-replication conflicts is not intrinsically protective or deleterious but is contingent upon the recombination landscape shaped by SOS induction. 🔗 buff.ly/bdhlupH

🦞 🧬 A resampling-based evaluation of the 79-SNP marker panel captures broad differentiation between European lobsters, Homarus gammarus and H. americanus. Find out more in #G3journal about this important tool built for #lobster genetics 🔗 buff.ly/vOvtQLr @marie-saitou.bsky.social

Happy birthday to George W. Beadle! A Nobel laureate and former GSA president, Beadle helped lay the foundation for molecular biology. GSA honors his legacy through the George W. Beadle Award, recognizing outstanding contributions to the genetics community: buff.ly/3FewQNa

🪱 Latest in #G3journal: A mutant analysis of #Celegans phosphatidylcholine (PC) synthesizing enzyme pcyt-1 and variants corresponding to disease-causing human mutations in the gene reveals how graded reductions in PC synthesis affect organismal physiology. 🔗 buff.ly/XmSK2hG

Submitting an abstract to present at #Dros27 is easier than you think! 🪰 Start with the science you have. Don’t aim for perfection—you can get feedback to polish or expand your work. Gather co-author details, payment, an email address for all transactions, and browse topics. 🔗: buff.ly/JUIs4lG

🚨 Last call! Nominations for the Hugo Bellen and Catherine Tasnier Drosophila Neurogenetics Lecture close tomorrow, October 22. Don’t forget to submit your nomination! 🔗: buff.ly/htPIQvZ Get a cash prize and travel costs covered to present at #Dros27. 🪰

🌟 Cool new story: #AGING is lost in mis-translation! 🪰 A #Drosophila study shows how mistranslated "bad" proteins can increase #lifespan in mated females. Discover more from @flybehaviour.bsky.social in the October issue of #G3journal about the positive effect of mistranslation: 🔗 buff.ly/WeNNkDF

New research in #GENETICS combines theory and forward-in-time simulations to understand polygenic adaptation and quantitative trait evolution. 🔗 buff.ly/QHquAsn

A transcriptomic analysis of a #yeast lineage that inherits long telomeres identifies a genome-wide transcriptional response induced by long telomeres, which are inherited across generations. Find out more in #GENETICS 🔗 buff.ly/0hbPoN7

🧬 Happy World CRISPR Day! From exploring new methods to publishing groundbreaking research, the GSA community is pushing the boundaries of gene editing. How is CRISPR shaping your research? Tell us below! ⬇️

🪱 Ever wondered why there are fewer bipartite expression systems in #Celegans? Read the latest from Michael Nonet in #GENETICS, where he describes new techniques to create homozygous reporter-driver lines without sacrificing the ability to use them combinatorially. 🔗 buff.ly/Unely3m

Ready to ace your next scientific job interview? Join FASEB Associate Director of Workforce Development CJ Neely on November 18 for practical strategies to showcase your strengths and make a lasting impression with employers. 🔗 buff.ly/gvZAs8e

How do multiple, seemingly redundant defense mechanisms against transposable elements coexist within a single genome? In #GENETICS, Yusuke Nabeka, Hideki Innan answer this question by integrating the evolutionary dynamics of transposons, piRNAs, and KZFPs into a mathematical model. 🔗 buff.ly/CMLgHsx

↔️ Swipe LEFT or RIGHT An egg-intrinsic mechanism determines sperm entry and paternal genome exclusion, resulting in either true fertilization or clonal propagation in #cobitis fish. Find the first direct in vivo cytological evidence of this in October #GENETICS issue: 🔗 buff.ly/24FtQ45

🪰💤 A series of genetic, thermogenetic, and pharmacological experiments establishes the role of AMPK-related kinase snrk in promoting #sleep by acting in a subset of wake-promoting cholinergic neurons in #Drosophila brain. Learn more in October #GENETICS issue: 🔗 buff.ly/x7s7LXY

🔗 The DRSC Integrative Ortholog Prediction Tool (DIOPT) provides a centralized portal for identifying inferred orthologs among major model organisms. Major updates made in the 10 DIOPT versions are summarized by @perrimonlab.bsky.social in the October #GENETICS issue. 🔗 buff.ly/9PiKfjE

New research in the October issue of #GENETICS probes the roles of the nascent polypeptide–associated complex (NAC) and the ribosome-associated Hsp70 system Ssb1/2 in #yeast mitochondrial protein import and proteostasis. 🔗 buff.ly/wfcqD0o

📣 Call for Nominations: The Gruber Genetics Prize recognizes a leading scientist, or up to three scientists, for groundbreaking contributions to genetics research. The prize includes a $500,000 award. 🔗 buff.ly/YrZcKrl Deadline: December 15, 2026.

Do populations evolve similar traits through the same or different genetic mechanisms? 🐠A #cavefish study identifies that repeated evolution comes from reusing a limited subset of genomic regions, affecting eye size, sleep, and feeding traits. Now live in October #GENETICS issue: 🔗 buff.ly/ae5YNB1

We’re closing out our #Worm27 speaker series with Asako Sugimoto (Tohoku University). Her lab investigates the mechanisms and evolution of cell division and chromosome organization. Join us in Kobe to hear more about her work! Learn more about the meeting: buff.ly/4QTkIEV

🪰 Read the featured study in the October #GENETICS issue, which shows how multiple cell-adhesion molecules (CAMs) with opposing regulatory roles function synergistically to fine-tune neurite morphogenesis during #Drosophila neural circuit assembly. 🔗 buff.ly/FE7DB0m 📷️ Qi Xiao

Introducing CVaR-OCS, a novel formulation of optimum contribution selection that directly incorporates the joint posterior distribution of estimated breeding values (EBVs) for optimization via Conditional Value at Risk (CVaR). Now live in the October issue of #GENETICS:🔗 buff.ly/o8rShft

There is still time to apply for the Drosophila Trainee Award! The award provides travel support of up to $1,000 for graduate students and postdoctoral fellows attending #Dros27. 🔗 Apply by October 29: buff.ly/Hq3M0Oc

A #Drosophila genetic screen featured in the October issue of #G3journal shows how Polycomb and Trithorax genes shape the rapidly evolving gene regulatory network responsible for dimorphic abdomen tergite pigmentation.  🔗 buff.ly/3QRlc0U 📷️ Thomas M Williams

Using Bayesian variable selection, QTL mapping, and context-dependent mediation analysis, researchers dissected genetic regulation of immune traits and their contribution to #COVID-19 disease severity in mice 🐭. Now live in the October issue of #GENETICS: 🔗 buff.ly/QVSTjpc

📣 Attention all educators! The latest Primers published in #GENETICS in 2026 cover mitochondrial protein cleanup, epigenetic inheritance, neuronal lipids, and QTL mapping. Explore these resources for bringing genetics concepts into the classroom: buff.ly/UKcDiR4

🪰 Discover the latest #Drosophila transcriptome in the October issue of #GENETICS It provides a high-resolution view of larval transcriptional regulation under normal and parasitic wasp–infested conditions, highlighting the roles of noncoding RNAs in innate immunity. 🔗 buff.ly/PBqbEvG

🪰 Copulatory wounds are injuries that arise during mating in insects. The October issue of #GENETICS features a #Drosophila model of copulatory wounds and their healing, offering a genetic system to study sexual conflict in the animal kingdom. 🔗 buff.ly/6YNlA89 📷️ Sophie Jalkut & Vicki Losick

Know an outstanding early career Drosophila neurogenetics researcher? Nominate them for the Hugo Bellen and Catherine Tasnier Drosophila Neurogenetics Lecture for #Dros27! Nominations close October 22. 🔗: buff.ly/I9LQcdS

📖 Want to learn about QTL mapping? Shizhong Xu's primer unpacks the basics of QTL mapping with the goal of making it accessible to audiences with limited statistical and genetic knowledge. Read more in October's #GENETICS issue: 🔗 buff.ly/RnpdAyS

New in #G3journal: A comparative analysis of histone organization in #yeast Ogataea polymorpha (used for industrial protein production) and O. haglerorum reveals new signatures, highlighting genome function differences occurring on a microevolutionary scale. 🔗 buff.ly/C2ZNE8M