Michael Gilman

Michael Gilman

@gilman.bsky.social

Scientist, entrepreneur, ex-biopharm exec, former FM radio jock, lifelong hockey fan, aspiring guitar player and mixologist, #immigrant. CEO, Arrakis Therapeutics and a variety of other things. https://www.michaelgilman.net/disclosures/

2.3K followers598 following1.9K posts

Michael Gilman reposted

Acyn
@acyn.bsky.social

OBAMA: He's got the White House looking like Saddam Hussein opened a Cheesecake Factory. It's gold everywhere.

Michael Gilman reposted

Aaron Rupar
@atrupar.com

“How much time do you think this defense secretary spends looking in the mirror in the morning? These are not serious people” — Obama’s audience in Ohio is hanging on every word as he skewers Trump and Hegseth

Michael Gilman
@gilman.bsky.social

A couple of first-time cocktails out of the bar this evening. I had a bunch of oranges, so I could make fresh-squeezed OJ, an ingredient I'd never used here. Anyhow, the most popular drink tonight was the...

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Michael Gilman
@gilman.bsky.social

And this one, which I think was invented by Perplexity, whom I asked for suggestions, is a riff on a mid-century gin sour recipe called the Army & Navy, in which OJ substitutes for some of the lemon. It was really good. Ping me for the recipe, if you're not offended by AI cocktails.

Michael Gilman
@gilman.bsky.social

A couple of first-time cocktails out of the bar this evening. I had a bunch of oranges, so I could make fresh-squeezed OJ, an ingredient I'd never used here. Anyhow, the most popular drink tonight was the...

Michael Gilman
@gilman.bsky.social

Ward Eight. This is a classic Boston cocktail, reportedly invented in 1898 at the not-so-long-gone Locke Ober Café in the Back Bay, originally made to celebrate the electoral victory of a famous Boston political boss. Rye, OJ, lemon juice and two teaspoons of Grenadine. Ended up making three.

Michael Gilman
@gilman.bsky.social

People do some crazy sh*t.

Andrea Devon@andreadevon.sheshed.rocks

Canadian cliff diver Molly Carlson just became the first woman to dive off an iceberg. Perfection! 📍 Newfoundland, Canada 🇨🇦 #SheShed #VivaHerAlliance

Michael Gilman
@gilman.bsky.social

I remember a faculty member when I was in graduate school (would have been early 80s) advocating for sequencing the dog genome to understand "the molecular biology of loyalty." This, sadly, is an unfortunate but entirely of-the-moment pivot.

Laura Howes@laurahowes.bsky.social

I did not have this on my "I imagine lots of scientists will pivot to get military funding in the coming years" bingo card. I'm not angry at myself for that oversight, just disappointed.

Michael Gilman
@gilman.bsky.social

Note two members of our industry.

Judd Legum@juddlegum.bsky.social

Ramaswamy has produced an attack ad weaponizing the rape of his opponent, Amy Acton, when she was 12 years old. It features Acton’s mother, who abandoned Acton after she was raped by her step-father, fleeing the state with her husband. Here is the corporate money helping fund that ad.

Michael Gilman
@gilman.bsky.social

As I try to hold on to a residual belief in the fundamental goodness of humanity, all I can think is that guys like this (sadly, there are plenty of them) become so coddled, so surrounded by yes-men (and women), so deeply into their own bubble of bullshit, that they lose all connection to reality.

Ben McAdams (The Resurrection Arc)@purrtah.bsky.social

Vivek is doubling down and doing a $4m ad buy for the Acton Mom ad which has been widely debunked and faced bipartisan backlash www.axios.com/2026/10/21/r...

axios.comExclusive: Ramaswamy doubles down on explosive ad featuring rival's mother, despite backlashRamaswamy is gambling that the deeply personal attack by Amy Acton's mother will resonate with voters.
Michael Gilman
@gilman.bsky.social

Perhaps a day to revisit that hellhole. Just in time for game day injury reports! Thank you, Ukraine.

Anonymous@youranoncentral.bsky.social

Russian bot traffic has dropped to nearly 0 after Ukraine struck a Yandex data center in Vladimir, Russia

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Michael Gilman
@gilman.bsky.social

And for the sake of completeness, tonight’s wine - 2017 Wingspan Moons of Neptune Zin. Know nothing about it, except that it’s been sitting in my “cellar” for a while. It was good!

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Michael Gilman
@gilman.bsky.social

Returning to cocktail programming, tonight I'm done with honey. This is a Brooklyn - a Manhattan riff, of course. The key ingredient, hard to find, is the French Amaro-ish liqueur Amer Picon. Fortunately, I have a French daughter-in-law, so I am well provisioned.

Michael Gilman
@gilman.bsky.social

Goalie goal!

NHL Goals@nhlgoals.bsky.social

Empty net goal for New York! Scored by Igor Shesterkin with 02:34 remaining in the 3rd period. New York: 5 Tampa Bay: 1 #TBLvsNYR #NYR #GoBolts

Michael Gilman
@gilman.bsky.social

Over here at House Gilman, I have just signed an executive order declaring that the moon is, in fact, made of green cheese. Anything else you may heard is a hoax. Or, to resurrect a golden oldie from the Nixon administration, it is "inoperative."

Michael Gilman
@gilman.bsky.social

I’m just gonna try to take this at face value for a moment. So if people pay their premiums and make no insurance claims, they’re committing fraud. Therefore, I’ve been fraudulently paying for home and auto insurance for decades. I’m in deep shit.

Aaron Rupar@atrupar.com

Assistant AG for Fraud Colin McDonald: "Apparently 35% of people have never even used their Obamacare account for any health services. That is a statistical impossibility and it's because these are not real people seeking real care. These are fraudsters."

Michael Gilman
@gilman.bsky.social

This story is powerful. You can readily understand the frustrations all around. Fortunately, a happy ending for little Hazel. This is not really a Vertex issue IMHO. Rather it reveals systemic cracks in our entire system of drug development, regulation, and healthcare delivery. How do we respond?

endpoints.newsIn a changed world for cystic fibrosis, a family's fight reveals a new gap in careDrugs like Trikafta, first approved in 2019, have changed cystic fibrosis from a death sentence to a manageable chronic condition for the vast majority of patients. But the drug is only approved for c...

Michael Gilman reposted

Chris Weston
@chrisweston.bsky.social

We would probably have raised them in anticipation of energy costs but ngl was too funny to imagine Trump reading we held them. Lol

Steve Peers@stevepeers.bsky.social

Bank of England holds interest rates www.bbc.co.uk/news/live/c6...

bbc.co.ukBank of England holds interest rates at 3.75%, but governor says high energy costs may lead to increaseSix members of the Monetary Policy Committee, which makes the decision, voted to hold the rate - while the other three wanted an increase to 4%.
Michael Gilman
@gilman.bsky.social

Privileged to be part of this long journey and to be able to serve people living with SMA. finance.yahoo.com/healthcare/a...

finance.yahoo.comScholar Rock Announces FDA Approval of ISEMBYLD™ (apitegromab-mstn), the First and Only Muscle-Targeted Treatment for Children and Adults with Spinal Muscular Atrophy (SMA)CAMBRIDGE, Mass., September 11, 2026--Scholar Rock (NASDAQ: SRRK), a global biopharmaceutical company dedicated to improving the lives of patients with rare, severe, and debilitating neuromuscular dis...

Michael Gilman reposted

Justin Wolfers
@justinwolfers.bsky.social

In 1937, Stalin's census found the famine killed millions.⁣ ⁣ His government suppressed the report and shot the statisticians who made it.⁣ ⁣ Three weeks ago, that kind of suppression was illegal in America. Now it isn't. https://newsletter.platypuseconomics.com/p/the-sentence-that-used-to-protect

newsletter.platypuseconomics.comThe Sentence That Used to Protect American Statistics"Protection from inappropriate influence is a hallmark of scientific integrity." That line governed the Census Bureau and then the White House quietly disappeared it.
Michael Gilman
@gilman.bsky.social

Dude misunderstands how insurance works. (Which I don't believe.)

Aaron Rupar@atrupar.com

Dr Oz on health insurance: "I'm gonna give you the money instead of buying you insurance ... look, why have a buffet offered to everybody if maybe a few people want À la carte service? 'I'm young, I don't have kids, I'm not married ... '"