Greg Madej

When the call came to conquer the München Halbmarathon, only TWO Structure Biologists from Regensburg answered. 21.1 km. No motion correction. No picking the best classes. And no way to improve the final result by clever data processing. Just raw, unfiltered suffering at full resolution.

Inspiring days in Sutton Bonington with Hydrosensing team. Great discussions, slightly too much fancy food, and a Saturday run that turned into an obstacle course, dodging cars that all drive on the wrong side of the road. Great collaborators becoming even better friends. @hydrosensing.bsky.social

Great to host my dear friend Uli Zachariae in Regensburg today. It’s always inspiring how much common ground exists between computational electrophysiology and cryo-EM: different methods, same questions about how proteins move, function, and shape life. #StructuralBiology #CryoEM #IonChannels

While visiting Regensburg, Ellie had a confidential side project: using a scoring pipeline for flavour, texture, and appearance, she identified top performers with the kind of confidence usually reserved for structure papers. Reviewer 2 has requested a larger sample size and more ice cream controls.

Well, I finally swapped the predictable pavement for some unpredictable trail running, and let's say my legs have feelings now—mostly bewilderment and slight betrayal. I'm back home, covered in dirt, slightly bruised. Most importantly, I didn't need to call for a helicopter. Success!

Nanocosmos: Faster Than Your Quickest Thought! "Physik goes Downtown Night 2025" featured science presented by speakers from RUN that was truly mind-blowing. They delivered fantastic talks about the movement of atoms at speeds that completely redefine "quick"! www.uni-regensburg.de/physik/schul...

The @ziegler-lab-ur.bsky.social delegation survived the Munich Half Marathon! This Trial of Spirit demanded the Force be strong with us. And the Force was extraordinarily strong with @katjaurbansky.bsky.social Her exceptional pace has earned her a promotion to the Council of cryoKnights - so cool!

Enjoy the picture to see moments from the visit — from the Robin Hood statue to the lab and evening strolls through Nottingham! 🌿 @uniregensburg.bsky.social 4/4

The visit highlighted the spirit of our project: connecting scientists across borders and disciplines to advance cutting-edge research together to uncover the mechanisms plants use to perceive water stress. 3/4

During this visit, Christine Ziegler @ziegler-lab-ur.bsky.social joined Malcolm Bennett in their lab at the University of Nottingham, while Eilon Shani @eilonshani.bsky.social also happened to be visiting the same research center — a perfect coincidence for a productive and friendly reunion! 2/4

I've just commissioned a cryoEM new coffee mug in new design. To be fair, the mug is arguably the more critical piece of equipment for data collection. You try imaging a membrane proteins at 5 AM without caffeine. ☕🔬#cryoEM

MC 2025: We came, we saw, we won🏆 🏆! Amazing team on a fantastic time at the Microscopy Conference in Karlsruhe. Get this: two of our posters won Poster Prizes! We're pretty sure it was our perfect blend of science and questionable doodles in the margins. @ziegler-lab-ur.bsky.social

Ultrafast Almost Gold! The Regensburg Center for Ultrafast Nanoscopy bio-section took second in the relay! Physics' reaction rates are attoseconds, but ours, Slower. Probably why "The Quantum Leapers" edged us out. Great fun and pretzels! @ziegler-lab-ur.bsky.social @katjaurbansky.bsky.social

So exciting … The publication where I had the privilege to contribute has been selected as an Editor's Choice. This recognition truly reflects everyone's hard work and dedication.

Recently, our early-career researchers agreed on the value of organizing regular sessions for PhDs and PostDocs to explore key research topics in greater depth. These sessions offer a space to understand the methods & techniques used across the 4 #Hydrosensing teams. #science

In the very 1st session this Tuesday, @greg-madej.bsky.social, from @uniregensburg.bsky.social @ziegler-lab-ur.bsky.social, presented how their expertise is applied within the project; specially the use of Cryo-EM in the study of membrane-embedded proteins. 🌐 www.uni-regensburg.de/biologie-vor...

Yesterday, through the tireless work of training runs, the support of my team, and the simple act of putting one foot in front of the other, we reached the finish line. The justice of completing what we set out to do, after the planning and the effort, has been served. @katjaurbansky.bsky.social

academic.oup.com/nar/article/... Proud to have been a small part of the team behind the latest publication. It was a privilege to collaborate with such a talented group of researchers on this work. A massive congratulations to all the authors for this contribution to the field! #RNA #cryoEM

Here is an update on our recent activity.. febs.onlinelibrary.wiley.com/doi/10.1002/...

In @uniofnottingham.bsky.social ERC Hydrosensing members spent a few intense (and wardrobe-consistent 😅) days filming about research on root systems and how plants adapt to drought. More footage for the documentary is being filmed at locations around the world in the coming year.

We had the pleasure to contribute to this publication... It was a pleasure to be part of this effort. Congratulations to all authors! #cryoEM @cmziegler.bsky.social @greg-madej.bsky.social pubs.acs.org/doi/full/10....

These were great days.. thank you all! @hamannlab.bsky.social @eilonshani.bsky.social @sara-morghen.bsky.social @francesco-saffioti.bsky.social @katjaurbansky.bsky.social @wiebkehaeger.bsky.social @michaelaticha.bsky.social @hydrosensing.bsky.social @hydrophotonics.bsky.social

First images coming soon 🤩

#HydroSensing Synergy Group - your fascinating talks last week completely watered the seeds of curiosity in my brain 😉. Prepare to see the photographic evidence of my descent into macroscale hydrosensing madness! I'm pretty sure my leafy friends 🌱 are judging my overly enthusiastic note-taking.

We are fascinated by how our leafy friends 🌱 feel the subtle shifts in soil moisture 💦 Last week we hydrated your minds and cultivated connections at our #erc meeting focusing on the captivating world of #Plant #HydroSensing 🧩@hydrosensing.bsky.social @hydrophotonics.bsky.social

After our annual #HydroSensing meeting in Regensburg, we went for a hike.. of course with a subsequent data collection and data processing demonstration 😁 #Plant #cryoEM

the cryo-clipping-box for JEOL cryoARM... easy! #cryoEM

We've been using SerialEM 4.2.0 beta on our JEOL cryoARM-200 for a while now. The multi-record setup and coma vs. IS calibration routines are particularly helpful – they're user-friendly and consistently reliable. #cryoEM #SerialEM

Just another Friday evening cryoEM screening.. with pizza 😁 #cryoEM

“LeCun, who earned his bachelor's and Ph.D. in France , said the changes in the United States should be a wake-up call for European institutions and companies. "You may have an opportunity to attract some of the best scientists in the world," he wrote.” www.businessinsider.com/meta-yann-le...

„Jugend Forscht 2025” the German outreach - it’s the youth science competition aiming to interest young scholars in science - this year also #cryoEM

⭐8 days left to apply for 👇 postdoc position ⭐ and join an international group of great people😊

temperature-controlled dewar from NanoSoft Materials (www.nanosoftmaterials.com). We are using it - no solidified ethane! Plus: if you happen to drop a grid in the brass cup the groove design on the bottom makes retrieval easy. Highly recommend. #cryoem #vitrification #microscopy #vitrobot

Welcome to the jungle, we got fun and games We got everything you want, honey, we know all the names.. www.wobblylabs.com/quantum-jungle

Mystery 2D class... friendly panda or grumpy fish? #cryoEM

📸 RIGHT: A tissue culture plate of tomato; one step in our journey to understanding plant resilience 🍅 📸 LEFT: Screening different CRISPR libraries in tomato tissue culture—hunting for key genes in sensing water and water stresses 🧬 3/3

Meet the #HydroSensing team from Regensburg! 🔬 From braving the cold room to battling centrifuges, our team tackles science with passion, precision, and just a little bit of chaos. Follow along as we take you behind the scenes! 👇 #ScienceLife #LabAdventures 1/8

✨We are hiring!✨🧪🏛️🧬 The @nhmdk.bsky.social at the University of Copenhagen is seeking a permanent, full-time Molecular Biology Lab Manager to help us establish and run our National Facility for #Museomics in the heart of one of Europe's most beautiful cities! Please reskeet!

Mystery Protein Challenge Calling all structural biology enthusiasts and #cryoEM aficionados! Can you identify the protein shrouded in this 2D class average? Hint: This protein plays a vital role in the respiratory chain.