Katrina Ray

Katrina Ray

@heykatray.bsky.social

Science, music, trashy TV & tap-dancing | Chief Ed - Nature Reviews Gastroenterology & Hepatology @natrevgastrohep.bsky.social | Opinions own | she/her/they | #LiverSky #gastrosky #gisky #MicroSky

2.9K followers1.4K following178 posts

Katrina Ray
@heykatray.bsky.social

All things gut health take centre stage in our May issue 👇 Beautiful cover by our Art Editor Laura Marshall, I find it somewhat hypnotic and soothing #gastrosky #liversky #microsky

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

Our MAY ISSUE is live! Consensus statement on gut health, dietary proteins and colonic disease, cholesterol metabolism, acute-on-chronic liver failure, and much more! www.nature.com/nrgastro/vol...

Katrina Ray reposted

Arc Institute
@arcinstitute.org

This new review from Core Investigator @christophthaiss.bsky.social & Innovation Investigator @maayanlevy.bsky.social maps how gut metabolites shape diseases from IBD to cancer, and lays out a framework for using them as therapies.

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! Metabotherapy for intestinal disease: using metabolites to prevent and treat disorders of the gut

dlvr.itMetabotherapy for intestinal disease: using metabolites to prevent and treat disorders of the gutNature Reviews Gastroenterology & Hepatology, Published online: 02 March 2026; doi:10.1038/s41575-026-01178-9Metabolites are important mediators of metabolism at the cellular and organismal levels. This Review explores the concept of metabotherapy, harnessing metabolites to prevent and treat gastrointestinal disorders, providing insights into metabolite classifications and their pathophysiological mechanisms in health and disease and mapping their potential as therapeutic targets.
Katrina Ray
@heykatray.bsky.social

And what a cracking set of covers they are! We have phenomenal Art editors working with us 🎨🖌️🖼️

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

It is time for a well-deserved break for the Editorial team over the holidays - the editorial office will be closed from now until 5th January 🎄🎁☃️ Thanks to all our authors, referees and readers, it's been a fantastic year. Check out our wonderful covers! www.nature.com/nrgastro/vol... #gastrosky

Katrina Ray
@heykatray.bsky.social

Our December issue is out! #liversky #gastrosky. Featuring a great cover by Richard Tibbitts inspired by the ‘Jekyll and Hyde’ roles of memory T cells

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

Our DECEMBER ISSUE is live! Hepatic T cells, microbiome and pancreatic cancer, portal hypertension and cirrhosis, metabolic and alcohol-related liver disease and much more! www.nature.com/nrgastro/vol...

Katrina Ray
@heykatray.bsky.social

#microsky 🧪

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! Gut virome dynamics: from commensal to critical player in health and disease

nature.comGut virome dynamics: from commensal to critical player in health and diseaseNature Reviews Gastroenterology & Hepatology, Published online: 05 November 2025; doi:10.1038/s41575-025-01134-zThe gut virome is a complex ecosystem and has a critical role in human health. This Review outlines gut virome composition and functional relevance, and its role in human health and disease. Methodological challenges in advancing our knowledge of the gut virome are also discussed.

Katrina Ray reposted

Pallett Lab UCL
@pallettlab.bsky.social

SOOOOO excited to see this online IN REAL-LIFE!! Here, we review the latest in hepatic tissue-resident #Tcell biology. We draw on a metaphor proposed by Robert Louis Stevenson [1886] to highlight the fact a cell can manifest different behaviours & actions depending on environmental context 🧪

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! Tissue-resident memory CD8+ T cells: master deciphers of the hepatic environment

nature.comTissue-resident memory CD8+ T cells: master deciphers of the hepatic environmentNature Reviews Gastroenterology & Hepatology, Published online: 22 September 2025; doi:10.1038/s41575-025-01118-zThis Review provides a comprehensive overview of the role of tissue-resident memory CD8+ T cells in hepatic immune responses, explores their dual function in liver immunoprotection and immunopathology, and discusses their therapeutic potential.
Katrina Ray
@heykatray.bsky.social

#gastrosky 🍎📃 #oncsky #liversky 🧪

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

ICYMI: New online! Food as medicine in gastrointestinal cancer therapy

nature.comFood as medicine in gastrointestinal cancer therapyNature Reviews Gastroenterology & Hepatology, Published online: 18 September 2025; doi:10.1038/s41575-025-01117-0Diet modulates not only gastrointestinal cancer risk but also survivorship, providing an opportunity to improve cancer-related outcomes and quality of life through suitable dietary and lifestyle interventions in survivors of cancer. This Comment summarizes the evidence and ongoing trials investigating diet in gastrointestinal cancer survival, including potential underlying mechanisms and future research directions.
Katrina Ray
@heykatray.bsky.social

#microsky #gastrosky 🧪

Prof Francine Marques@fzmarques.bsky.social

Our new @natrevgastrohep.nature.com review is now online "Parental diet and offspring health: a role for the gut microbiome via epigenetics" Co-authors Chaoran Yang, @mattsnelson.bsky.social & Sam El-Osta A fascinating area of research with lots of potential nature.com/articles/s41...

nature.comParental diet and offspring health: a role for the gut microbiome via epigenetics - Nature Reviews Gastroenterology & HepatologyIn this Review, Marques and colleagues discuss the evidence regarding the effects of parental diet on the health of offspring, with a focus on how changes to the gut microbiome alter epigenomic respon...
Katrina Ray
@heykatray.bsky.social

Cracking new issue out now! And a great cover drawn many Neil Smith, I really want a gut chopping board now! #gastrosky

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

Our August issue is live! Gut microbiome & nutrition, menopause & gastrointestinal health, alcohol-related liver disease, enteric nervous system & much more! www.nature.com/nrgastro/vol... #gastrosky #liversky #microsky

Katrina Ray
@heykatray.bsky.social

🧪 #microsky #gastrosky #microbiome

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! Credible inferences in microbiome research: ensuring rigour, reproducibility and relevance in the era of AI

nature.comCredible inferences in microbiome research: ensuring rigour, reproducibility and relevance in the era of AINature Reviews Gastroenterology & Hepatology, Published online: 31 July 2025; doi:10.1038/s41575-025-01100-9Artificial intelligence (AI) is a powerful tool that could be applied to microbiome research. This Perspective discusses best practices and current limitations with the application of AI in microbiome data research, giving insights into future use and practical advice and recommendations on its use.
Katrina Ray
@heykatray.bsky.social

Fascinating paper in @lancetgastrohep.bsky.social - The expectation of eating gluten/wheat played a major part in symptoms "IBS patients with self-perceived gluten sensitivity reacted similarly to gluten, wheat, and sham challenges" www.thelancet.com/journals/lan... #gastrosky

thelancet.comEffect of gluten and wheat on symptoms and behaviours in adults with irritable bowel syndrome: a single-centre, randomised, double-blind, sham-controlled crossover trialIBS patients with self-perceived gluten sensitivity reacted similarly to gluten, wheat, and sham challenges. These findings suggest that expectations played a major role in symptom generation, and tha...
Katrina Ray
@heykatray.bsky.social

🧪

Fola May MD PhD@drfolamay.bsky.social

So great to see this labor of love published! 👉🏾 rdcu.be/exb0r Honored to work w/ #SamirGupta, #WintaMehtsun, & #AhmedinJemal on a comprehensive overview of Black–White #disparities across the #CRC continuum in the US @natrevgastrohep.nature.com @nature.com #colorectalcancer @dgsomucla.bsky.social

rdcu.beBlack–White disparities across the colorectal cancer care continuum in the USANature Reviews Gastroenterology & Hepatology - In the USA, colorectal cancer (CRC) is a leading cause of death and a public health challenge due to persisting disparities between Black and...
Katrina Ray
@heykatray.bsky.social

An important topic #gastrosky #oncsky 🧪

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! Black–White disparities across the colorectal cancer care continuum in the USA

nature.comBlack–White disparities across the colorectal cancer care continuum in the USANature Reviews Gastroenterology & Hepatology, Published online: 21 July 2025; doi:10.1038/s41575-025-01087-3In the USA, colorectal cancer (CRC) is a leading cause of death and a public health challenge due to persisting disparities between Black and White individuals. This Review examines Black–White disparities in CRC outcomes, bringing health-care and systemic inequities into focus.
Katrina Ray
@heykatray.bsky.social

#IBDsky #gastrosky

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! The global burden of inflammatory bowel disease: from 2025 to 2045

nature.comThe global burden of inflammatory bowel disease: from 2025 to 2045Nature Reviews Gastroenterology & Hepatology, Published online: 18 July 2025; doi:10.1038/s41575-025-01097-1The global burden of inflammatory bowel disease (IBD) is shifting as countries transition through four epidemiologic stages. This Perspective explores the global evolution of IBD over the next 20 years and proposes strategies for prevention and health-care innovation.
Katrina Ray
@heykatray.bsky.social

Fresh out! #microbiome #microsky #gastrosky

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! Intestinal pH: a major driver of human gut microbiota composition and metabolism

nature.comIntestinal pH: a major driver of human gut microbiota composition and metabolismNature Reviews Gastroenterology & Hepatology, Published online: 02 July 2025; doi:10.1038/s41575-025-01092-6In humans, pH varies across the gastrointestinal tract. This Review provides an overview of gastrointestinal pH and its role in shaping the gut microbiota, highlighting major physiological and dietary factors that influence gastrointestinal pH and how in turn pH affects microbiota composition and metabolism in health and, potentially, disease.
Katrina Ray
@heykatray.bsky.social

🧪

Cincinnati Children's Allergy and Immunology@cincykidsallergyim.bsky.social

The esophagus has been viewed as a simple tube for food. We present evidence that the esophagus is an immune organ with extensive sensing properties designed to tolerate and mount defenses against antigenic and biophysical challenges. rdcu.be/eueRE @natrevgastrohep.nature.com

rdcu.beThe oesophagus as an immune organNature Reviews Gastroenterology & Hepatology - This Perspective article provides a detailed overview of the oesophagus as an immune organ, highlighting its innate immune components and sensing...

Katrina Ray reposted

Nature Reviews Gastroenterology & Hepatology
@natrevgastrohep.nature.com

New online! Lessons from incretin-based therapy in MASH and obesity

nature.comLessons from incretin-based therapy in MASH and obesityNature Reviews Gastroenterology & Hepatology, Published online: 27 June 2025; doi:10.1038/s41575-025-01096-2Glucagon-like peptide 1 receptor agonists are effective pharmacotherapies for the treatment of obesity and related disorders. In metabolic dysfunction-associated steatohepatitis with moderate to advanced fibrosis, semaglutide improved liver histology over 72 weeks. In another new study, tirzepatide was superior to semaglutide in reducing body weight in individuals with obesity.
Katrina Ray
@heykatray.bsky.social

🚨 attention all early career researchers! Check out this new award, details below Super excited to be on the judging panel for the gastrointestinal and inflammatory diseases section #gastrosky #liversky 🧪

Nature Portfolio@natureportfolio.nature.com

Applications are now open for the 2026 Takeda Innovators in Science Award with Nature. Early-career researchers in GI & inflammatory disease, neuroscience or oncology: Win a share of US$400K and earn global recognition. Apply today: go.nature.com/4jBp3oM #Academicsky

Katrina Ray
@heykatray.bsky.social

#liversky

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! Promise and pitfalls of liver xenotransplantation

nature.comPromise and pitfalls of liver xenotransplantationNature Reviews Gastroenterology & Hepatology, Published online: 19 June 2025; doi:10.1038/s41575-025-01093-5Liver xenotransplantation and genetically engineered pig livers have potential to save human lives. Liver xenotransplants can either act as a bridge to allotransplantation or support the recovery and regeneration of a whole or reduced native liver in acute liver failure and in major hepatectomies through ex vivo perfusion or auxiliary liver xenotransplantation.
Katrina Ray
@heykatray.bsky.social

#gastrosky

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! The oesophagus as an immune organ

nature.comThe oesophagus as an immune organNature Reviews Gastroenterology & Hepatology, Published online: 18 June 2025; doi:10.1038/s41575-025-01086-4This Perspective article provides a detailed overview of the oesophagus as an immune organ, highlighting its innate immune components and sensing mechanisms that maintain homeostasis and barrier integrity while responding to antigenic and biophysical challenges.
Katrina Ray
@heykatray.bsky.social

#liversky #medsky #alcohol

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! Public health policies to prevent alcohol-related liver disease

nature.comPublic health policies to prevent alcohol-related liver diseaseNature Reviews Gastroenterology & Hepatology, Published online: 04 June 2025; doi:10.1038/s41575-025-01084-6There is clear evidence that public health measures to reduce alcohol consumption are effective, which can have a positive effect on alcohol-related liver disease. In this Perspective, Parker and colleagues discuss public health policies that affect alcohol consumption and alcohol-related liver disease.
Katrina Ray
@heykatray.bsky.social

🧪 #gastrosky #microsky

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! The gut microbiome connects nutrition and human health

nature.comThe gut microbiome connects nutrition and human healthNature Reviews Gastroenterology & Hepatology, Published online: 04 June 2025; doi:10.1038/s41575-025-01077-5In this Review, Sanz and colleagues discuss how diet shapes the gut microbiome, the role of diet–microbiome interactions on the immune, nervous and cardiometabolic systems, and implications for dietary guidelines and precision nutrition.
Katrina Ray
@heykatray.bsky.social

Our June issue is live and it’s a cracker - a Focus issue dedicated to #IBD. Check it out selected content is FREE for 1 month! 🧪 #IBDsky #gastrosky #medsky

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

Our JUNE FOCUS ISSUE ON IBD is live! IBD therapeutics, Crohn's disease & gut microbiota, biological sex & IBD, IBD management & public health, and much more! www.nature.com/nrgastro/vol...

Katrina Ray reposted

Rashid Lui 雷諾信
@rashidlui.bsky.social

Delighted to share our thoughts on the emerging discipline of #oncogastroenterology in @natrevgastrohep.nature.com #CUHKMedicine #GIoncology #oncology www.nature.com/articles/s41...

nature.comRedefining cancer care: the case for an onco-gastroenterology subspecialty - Nature Reviews Gastroenterology & HepatologyOnco-gastroenterology is defined as a collaborative subspecialty of Gastroenterology that is dedicated to the unique needs of individuals with or at risk of cancer, with a focus on maintaining and man...
Katrina Ray
@heykatray.bsky.social

#Liversky 🧪

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! Hepatic stellate cells: balancing homeostasis, hepatoprotection and fibrogenesis in health and disease

nature.comHepatic stellate cells: balancing homeostasis, hepatoprotection and fibrogenesis in health and diseaseNature Reviews Gastroenterology & Hepatology, Published online: 22 May 2025; doi:10.1038/s41575-025-01068-6Hepatic stellate cells (HSCs) are best known as the primary fibrogenic liver cell type. This Review provides a comprehensive overview of protective and pathogenic HSC functions in health and disease and discusses novel therapeutic concepts derived from this dual role.
Katrina Ray
@heykatray.bsky.social

#Gastrosky #microsky

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

New online! The role of the enteric nervous system in the pathogenesis of Clostridioides difficile infection

nature.comThe role of the enteric nervous system in the pathogenesis of Clostridioides difficile infectionNature Reviews Gastroenterology & Hepatology, Published online: 22 May 2025; doi:10.1038/s41575-025-01071-xThis Perspective highlights emerging evidence of an interaction between Clostridiodes difficile and the enteric nervous system (ENS) during infection, discussing underlying mechanisms and how the ENS and extrinsic innervation are affected by C. difficile infection and toxins and how ENS responses contribute to pathogenesis and disease outcomes.

Katrina Ray reposted

Nature Reviews Gastroenterology & Hepatology
@natrevgastrohep.nature.com

Early Crohn’s disease: can we change the disease course? Geert D'Haens & Melek Simsek discuss this topic in their new Clinical Outlook www.nature.com/articles/s41... Free to read: rdcu.be/eml63 #IBDsky #Gastrosky #Medsky

nature.comEarly Crohn’s disease: can we change the disease course? - Nature Reviews Gastroenterology & HepatologyCurrent treatments for Crohn’s disease prioritize early intervention with biological therapies, with several landmark trials demonstrating that starting biologic agents within the first years of diagn...
Katrina Ray
@heykatray.bsky.social

🧪

Nature Reviews Gastroenterology & Hepatology@natrevgastrohep.nature.com

Seen at #DDW2025, this Perspective by @pieterdorrestein.bsky.social & co on the changing metabolic landscape of bile acids www.nature.com/articles/s41... 🔓 link: rdcu.be/ekTBV #Gastrosky #microsky #microbiome

nature.comThe changing metabolic landscape of bile acids – keys to metabolism and immune regulation - Nature Reviews Gastroenterology & HepatologyBile acids have important roles in human metabolism and immune regulation. In this Perspective, Dorrestein and colleagues discuss the technologies and data science-related approaches that are improvin...