HittingerLab

I am honored to be chosen as the new Eddie Goldenberg Research Chair of Canada in Biodiscovery, Biodesign, and Bioproduction at University of Guelph as part of the Canada Global Impact+ Research Talent Initiative! @UofGuelphNews, @UofG, @UofGResearch

As part of my new chair and centre @uofguelph.bsky.social , we are recruiting a new Assistant Professor through the Canada Impact+ Emerging Leaders program: careers.uoguelph.ca/job/Guelph-A...

Resistance to antifungal medications is growing. Now, #UofG researchers have developed a faster way to identify the genetic vulnerabilities of Candida fungi, which could lead to brand new treatments. @uofgcbs.bsky.social @uofgresearch.bsky.social uoguel.ph/vze5i

Backed by $8M in federal funding, Dr. Chris Todd Hittinger will be the new Eddie Goldenberg Research Chair of Canada in Biodiscovery, Biodesign and Bioproduction at #UofG as part of the Canada Global Impact+ Research Talent Initiative. His appointment begins on July 1, 2027: https://uoguel.ph/3nw8s

A tenure-track research position is available for application at the Westerdijk Fungal Biodiversity Institute @westerdijkinst.bsky.social located in Utrecht Science Park in the Netherlands. Please share with colleagues and see the link below for more info: wi.knaw.nl/news/details...

A new study out with @linder-surprise.bsky.social and @rokaslab.bsky.social in iScience across ~300 yeast species confirms the correlation between glucose uptake rate and cell surface-to-volume (SA:V) ratio, but suggests a link to other traits (growth rates and genome size). doi.org/10.1016/j.is...

Check out this new first-author paper from our new postdoctoral lab member @alyahussain.bsky.social! 🎉 This work is from her PhD in the Michael McMurray lab at CU Anschutz.

Two members of the Hittinger Lab received awards during the annual All-Wisconsin Energy Institute (WEI) meeting. Our lab manager, Amanda Hulfachor, won the Excellence Award and Sam Davison, a CMB graduate student, won the award for Community Impact. Congrats to both - we are very proud!⭐⭐⭐

#PYFF9 is coming to Valencia! 🇪🇸 Join us for the 9th International Conference on Physiology of Yeasts and Filamentous Fungi (PYFF9), Sept 8–11, 2026! ✨ Cutting-edge science, vibrant networking, and the charm of the Mediterranean—don’t miss it! 🔗 Learn more: efbiotechnology.org/pyff

There's a story behind every project that doesn't get fully captured in the final paper. Check out our "behind the paper" accompanying our paper on convergent evolution of aerobic fermentation in yeast. communities.springernature.com/posts/learni... @hittingerlab.bsky.social @rokaslab.bsky.social

With @linder-surprise.bsky.social and the @rokaslab.bsky.social, we evaluated glycolytic rates in 299 species using a newly developed ECAR assay. Genes retained by S. cerevisiae were highly expressed in Sat. dispora, indicating the CE of aerobic fermentation. link.springer.com/article/10.1...

So pleased to share that this project identifying convergent evolution of aerobic fermentation in a poorly characterized genus of yeasts (Saturnispora) is now out in @embojournal.org @hittingerlab.bsky.social @rokaslab.bsky.social @glbioenergy.bsky.social link.springer.com/article/10.1...

Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes @hittingerlab.bsky.social , @linder-surprise.bsky.social et al show how distinct genetic routes can converge on the same genetic outcome link.springer.com/article/10.1...

Congratulations to @maxhaase.bsky.social on his recent publication from his time in the Boeke Lab at NYU, where he used methods from the Y1000+ consortium! 🥳 We are very proud to have had him as an undergraduate student in our lab. med.nyu.edu/research/boe...

With the @rokaslab.bsky.social, three novel whole genome duplication (WGD) events were discovered in the Saccharomycotina yeast species in the Dipodascales clade. Before now, only four WGD events were known in fungi. This work suggests WGD may be underreported. www.sciencedirect.com/science/arti...

We're excited to announce that Chris will be attending the Yeast Genetics Meeting organized by the Genetics Society of America (GSA) @genetics-gsa.bsky.social in CA on June 13-17! #Yeast26 If you are interested in attending or presenting, follow this link to register! genetics-gsa.org/yeast-2026/

How much do growth morphologies in the Saccharomycotina subphylum vary? 🤔 With the @rokaslab.bsky.social, integrated datasets of 1,051 species were examined to assess filamentation evol. history and variation. ML models predicted morphologies with 70% accuracy. academic.oup.com/femsyr/advan...

In collaboration with the Pfleger Lab, Josh Dietrich et al. investigated 2-ketoacid decarboxylase (KDC) substrate specificities to identify KDCs with preference for 2-ketoisovalerate over pyruvate. This work will help guide future S. cerevisiae engineering efforts. urldefense.com/v3/__http://...

Congratulations to our wonderful PI, Chris Todd Hittinger, on receiving the Vilas Mid-Career Investigator Award from the UW–Madison Laboratory of Genetics! This recognition highlights his continued excellence in research, teaching, training, and mentorship. 🎉 genetics.wisc.edu/2025/12/09/d...

New preprint with @rokaslab.bsky.social! We used genomic, metabolic, environmental, and phenotypic data sets from 1,154 Saccharomycotina strains to asses filamentation variability and predict filamentation types across the subphylum. 🧩 www.biorxiv.org/content/10.1...

Gonçalves, @rokaslab.bsky.social @hittingerlab.bsky.social et al. surveyed 1,154 yeast genomes to examine gene repertoires linked to genome stability and elevated evolutionary rates, showing hypermutators persist across macroevolutionary timescales. 🔗 doi.org/10.1093/molbev/msaf285 #evobio #molbio

New work led by members of the @rokaslab.bsky.social! ☺️ 1,154 yeast genomes in the Saccharomycotina subphylum were surveyed for their relationship between reduced gene repertoires broadly associated with genome stability functions and elevated evolutionary rates.🧬 academic.oup.com/mbe/advance-...

This work has also been featured on the DOE Science News Source initiative, Newswise, which promotes credible research news to the public. By publishing accessible summaries of recent studies that reach thousands of media outlets, it helps experts share their work with a broader audience.

What started as a project characterizing variation in metabolic rates across yeasts turned into an interesting story about convergent evolution acting on the same key genes through distinct molecular mechanisms with @hittingerlab.bsky.social & @rokaslab.bsky.social. www.biorxiv.org/content/10.1...

We often talk about THE whole genome duplication in yeasts, but we find new evidence of additional whole genome duplications in other yeast species! Check out this preprint led by @kylethedavid.bsky.social www.biorxiv.org/content/10.1...

With the Opulente Lab at Villanova Univ., we describe a new yeast species: Lachancea rosae sp. nov. f.a., isolated from the hip bud of a wild California rose 🌹. This species unique traits adds to the biodiversity of the Lachancea genus. Open access article: onlinelibrary.wiley.com/doi/10.1002/...

New #Yeast paper out from the series #FantasticYeasts!!! @hittingerlab.bsky.social , Dana Opulente & team describe a novel species, Lachancea rosae, isolated from the wild rose Rosa californica 🌹 onlinelibrary.wiley.com/doi/10.1002/...