HUMAN Doctoral Network

HUMAN Doctoral Network

@human-dn.bsky.social

Official Bluesky account of the EU Horizon-funded Marie Curie Actions Doctoral Network H.U.M.A.N. We're leveraging metabolomics for blood analysis! Find out more about us and our (lab) work: human-dn.eu and LinkedIn! Instagram: @humandn_ X: @human_dn

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As Klidel wraps up her time in the HUMAN Doctoral Network, she reflects on diversity, diplomacy, ion mobility, nanoLC, multiomics, and a career goal that never changed: industry. Next stop, mass spectrometry method development and difficult analytical problems. We wish you all the best!🙌

Smaller samples, broader metabolite coverage. 🩸🔬 This week’s #HUMAN #Weekend Read from our DC Pauline Couacault highlights a non-targeted #metabolomics workflow combining RPLC and HILIC for blood #microsamples, with a single extraction applicable to both DBS and VAMS. Curious? 🔗bit.ly/4xpevAN

The HUMAN Doctoral Network is heading to #IMSC2026 in Lyon! 🧪 Our researchers will present work on integrated multi-omics, multimodal TIMS-MS, LC-MS/MS networking, and volumetric microsampling. Come find our talks and posters and connect with us! #metabolomics #massspectrometry #networks

HUMAN made its #ASMS debut in sunny San Diego! ☀️ Michael Witting, Klidel Rellin, and Marlene Thaitumu presented their work on reference material metabolomics, integrated multiomics, and blood microsampling. 🔬🧬 #ASMS2026 #Metabolomics #Multiomics #MassSpectrometry #HUMANDN #MSCA

How does high-intensity #exercise reshape the human metabolome? 🔥 This systematic review of 20 studies maps the major shifts in energy, carbohydrate, lipid, amino acid, and TCA cycle #metabolism, while highlighting key methodological gaps in exercise #metabolomics. Read: bit.ly/4aruSm9 #weekend

Throwback from Lille! DCs Pauline Couacault (Helmholtz Munich) and Sandra Costa (INRAE) were at RFMF 2026 back in May, sharing new perspectives in metabolomics, fluxomics, and metabolic network analysis. 🧬🔬 #Metabolomics #Fluxomics #HUMANDN #RFMF2026 #MSCA

Sara Londoño is closing her chapter with the HUMAN Doctoral Network after three years of research, collaboration, mentoring, and plenty of unexpected turns along the way. We are excited to see where clinical research or industry R&D takes her next. ¡Nuestros mejores deseos y mucha suerte, Sara!

#MetSoc2026 has concluded and we have another awardee! Congratulations to our DC, Daniel Silva, for receiving a Student Travel Award! He presented a talk on mapping the metabolome from blood microsamples using data from multi-platform labs within the HUMAN Consortium. Well done! 👏 #metabolomics

1/2 HUMAN is heading to #Metabolomics2026 in Buenos Aires! Our network will be represented across keynotes, talks, workshops, posters, and lunch seminars, covering metabolomics, lipidomics, ion mobility, multi-omics, open research, and translational applications. Come connect with us!

PhD is not just science, it’s project management and stress mitigation combined. Our DCs Marlene, Sara, Philippine, and Pauline get candid about what’s like to be a HUMAN PhD while keeping their sanity and stress levels in check. 👇 What's the most underrated stress-management tip you swear by?

We're going to San Diego! 🌊☀️ If you're heading to #ASMS this year, come find us — we'd love to connect, chat science, and maybe grab a coffee in between sessions ☕🔬 See you there! 👋 #ASMS2026 #Metabolomics #MultiOmics #TeamMassSpec #HUMAN

"What do you like about the HUMAN Doctoral Network?" We asked our DCs and PIs what their thoughts are and we're sharing them with you today! How about you? What do you like about the HUMAN Network? Let us know in the comments below! ⬇️

1/2 We have an announcement to make. 📢 As we approach the end of the project (and by extension, our PhD contracts), we're slowing down our social media presence. 👋 Most of our DCs now are sprinting towards the finish line and we would like them to focus on that goal. 🎯

2/2 You may see this as less posts and updates from our side. But we do have better end-of-project content planned, so stay tuned‼️ It's been wonderful running the online handles on behalf of the HUMAN Consortium. Thank you for the support (on- and offline)! 🙏 ✨ #HUMAN #MSCA #metabolomics

Are we born with metabolic advantages that fade over time? Liu et al., 2025 (Aging Cell) show that human umbilical cord plasma contains metabolites linked to healthy aging. 211 candidates identified. Several decline with age. Some extend lifespan in C. elegans. #Longevity #Metabolomics

Metabomeeting 2025 recap ✨ Posters, science, and great discussions in metabolomics and lipidomics. Huge well done to the team for sharing their work and representing their groups so well. On to the next experiments and discoveries! 🔬 #metabolomics #science #metabomeeting

Can one drop of blood track exercise metabolism?🤔 A 2025 Metabolomics study suggests dried blood spots🩸 can reflect key exercise-driven shifts in glycolysis, lipid use, mitochondrial pathways, and purine metabolism, using simple self-sampling. Curious? 🔗bit.ly/4q84mEf #microsampling #exercise

An appreciation post to the women of the HUMAN consortium. 🎉 Nine out of 12 of our DCs are women from all over the world, and they are mentored and supported by brilliant women across the network! Cheers to all the women and girls in STEM!🥂

Patient-centric blood sampling is moving diagnostics beyond the clinic 🧪 Capillary, at-home collection can widen access, lower burden, and support decentralized care 🌍. Read here: 🔗https://bit.ly/4pYIwnd #metabolomics #patientcentric #noninvasive

New study confirms that tiny dried blood samples (BμS) are a viable alternative to plasma for global metabolic profiling. The Mitra device stood out, providing comparable, and in some metrics, richer metabolic information. Big step toward less-invasive testing! Curious? 🔗 bit.ly/4pU6Hmw

HUMANs in #Madrid for our 3rd Annual Meeting 🇪🇸✨ Three days of science, discussions, workshops, lab tours, and great company at Universidad CEU San Pablo. Huge thanks to CEMBIO and Bright Giant—and to all our DCs for sharing their latest progress! #metabolomics

🚀 New Year, new Weeked Read! New study shows that tiny blood volumes collected with Mitra, Capitainer, and Whatman devices can deliver richer, more stable metabolic profiles than plasma—capturing key redox biomarkers like glutathione and ergothioneine. Curious? 🔗bit.ly/4q9cJAO #microsampling

Sorry to get you all excited, but due to some scheduling issues, this webinar would have to be rescheduled. 🙇‍♀️ ❗No webinar this Friday, 12.12.25❗

HUMAN Doctoral Network@human-dn.bsky.social

Don’t miss this--our final webinar for the year!🔴 The HUMAN Doctoral Network hosts Dr. Panteleimon G. Takis for a deep dive into Large-scale NMR Metabolomics. 📅 12 December 2025 | 13:00 CET 🔗 bit.ly/humandn_webinars #webinars #nmr #metabolomics

A new study shows that adduct type can totally change MS/MS fragmentation, reshaping how we interpret spectra, build molecular networks, and train AI models. 👉 It’s time for adduct-aware metabolomics. 👉 Read more: bit.ly/46MuLRM #MassSpec #Metabolomics #AnalyticalChemistry #Science

#Weekend Read 🔦The “dark metabolome” isn’t a myth, it’s a frontier. New research shows most unannotated signals in metabolomics are **not just fragmentation artefacts**, but real, undiscovered molecules. 🚀 🔗bit.ly/4pSxDUD #Metabolomics #DarkMetabolome #MassSpec

🔬 Piercing the secrets of tumors: New nanoneedle tech can “imprint” living tissue, mapping lipid changes in space & time. It can: ✅ Distinguish healthy vs cancer tissue ✅ Predict glioma grade ✅ Track chemo response in real time 🔗bit.ly/3KqOwpd #Nanotechnology #CancerResearch #Lipidomics

New #HUMAN paper out! 🩸 Our partners from CEMBIO explored blood microsampling (DBS, qDBS, VAMS) for untargeted #lipidomics using high-throughput LC-MS. Volumetric devices show plasma-like precision & recovery! 🔗bit.ly/476qWXw

What if Heisenberg had a mass spec? Would he be interested in #meth-abolomics? This latest #Weekend Read, explores how plasma metabolomics and bioinformatics modeling can uncover the hidden biological signatures of chronic methamphetamine use. 📖 Curious? 🔗bit.ly/3InEYdS #metabolomics

#Weekend Read #Metabolomics annotation is hard. And JESTR attempts to makes it easier by treating molecules & spectra as two views of the same object — and ranking candidates with joint embeddings. Result? Big gains over some existing annotation tools! Curious? 🔗bit.ly/4mdd4PB

Metabolites ≠ genes. 🔬 Using gene-centric pathway tools for metabolomics can mislead. In this commentary, we highlight 5 key pitfalls—from poor co-regulation to analytical gaps—and suggest ways forward, including rigorous annotation & metabolic flux analysis. Read here: bit.ly/3I1jPpE #weekend

The Analytical Scientist’s 2025 Power List dropped a few weeks ago and we’re ecstatic that ❗three ❗ of our HUMAN PIs got into the Top Ten for the topic: "What should be done to help analytical science rise to prominence as the keystone of all good science?" 1/3

Read the whole essays: 🔗https://theanalyticalscientist.com/power-list/2025/what-should-be-done-to-help-analytical-science-rise-to-prominence-as-the-keystone-of-all-good-science/ For the full 2025 Power List: 🔗https://theanalyticalscientist.com/power-list/2025/ 3/3

Weekend Read Alert❗ In this paper, single-cell mass cytometry was used to labelled glucose and glutamine in breast cancer cells, uncovering 40 active metabolites and revealed flux heterogeneity invisible to traditional methods! Curious? 🔗 bit.ly/3JFQjGr #metabolomics #singlecell #weekend

Exciting progress in computational metabolomics! The newly introduced Computational Metabolomics Reference Vocabulary (CMRV) offers a unified, community-driven language to describe tools, workflows, and data types across the field. Curious? 🔗bit.ly/4l5VcGl #metabolomics #weekendread