ISB

🔥 Ignite STEM is coming! Join ISB on December 2 to celebrate science education, the next generation of innovators, and the people who make it all possible. Learn more and register at isbscience.org/events/ignit....

At the latest @isbscience.org Research Roundtable, Dr. Jim Heath shared new findings connecting #LongCOVID to immune dysfunction and autoimmune diseases, and explained how AI could accelerate the search for answers. 🎥 See the recording and read the findings: https://bit.ly/4sfApVv

My excellent colleague at @isbscience.org, @flash-point.bsky.social, is hiring a Research Associate to work on elucidating mechanisms by which gut microbial metabolites impact human physiology and health. Please share/apply! 👇 isbscience.bamboohr.com/careers/72

What can immune cells tell us about #LongCOVID? And how might #AI help scientists find answers? ISB's Jim Heath shares discoveries and a promising approach to accelerating research. Read the recap and watch the talk: isbscience.org/news/infecti...

Join us December 9! Learn more and register today! isbscience.org/events/front...

Starting at noon Pacific! Why do Long COVID symptoms persist long after infection? Join ISB President Jim Heath for a free, public-friendly Research Roundtable exploring new clues from the immune system. Live Q&A included. Register: isbscience.zoom.us/webinar/regi...

Tomorrow at noon PT: Join ISB President Jim Heath for a free virtual Research Roundtable on emerging #LongCOVID research, immune responses and the upcoming NIH-sponsored Long COVID Hackathon. Register: isbscience.zoom.us/webinar/regi...

We are hosting a symposium at @isbscience.org in December on the frontiers of computational biology, with a focus on "AI, Multi-Omics, and the Future of Human Health." Join us! Virtual is free and it's $50 if you want to join in-person. isbscience.org/frontiers-in...

What can the immune system tell us about #LongCOVID? Join ISB President Jim Heath, PhD, Oct. 13 for a free virtual Research Roundtable on persistent immune responses, autoantibodies and an upcoming NIH-sponsored Long COVID Hackathon using RECOVER data. Register: isbscience.zoom.us/webinar/regi...

Science Seminar on 1 October 4 PM London / 11 AM EAST with Dr. Jared Roach, a Senior Research Scientist at the Institute for Systems Biology (ISB): #Metabolic #Health. Please register at shorturl.at/wxkbC @isbscience.org

Congrats, @rupaimmanuel.bsky.social!

Come join us!

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Meet Vedhika Sathish! Vedhika is a senior at Eastlake HS in WA who participated in our System Thinkers in STEM Ambassadorship. Check out Vedhika’s STiSA project: see.isbscience.org/projects/ved... #STEMsystemsthinkers @isbscience.org

Why do some people develop harmful autoantibodies after COVID-19? New ISB-led research in Immunity traces their production to a distinct population of B cells and reveals striking connections to autoimmune disease. isbscience.org/news/infecti... @cellpress.bsky.social @cp-immunity.bsky.social

Congratulations to ISB Distinguished Investigator and 2025 Nobel laureate Mary Brunkow, who has been named to Forbes’ 2026 “50 Over 50” Innovation list, recognizing women making significant contributions later in their careers. www.forbes.com/sites/maggie...

Meet Atalay Turkarslan! Atalay is a senior at Eastside Prep in WA who participated in our System Thinkers in STEM Ambassadorship. Check out his STiSA project: see.isbscience.org/projects/ata... #STEMsystemsthinkers @isbscience.org

Exciting collaboration with @annabiosys.bsky.social's lab just went online. @isbscience.org metaSPLiT: a fast, efficient, and relatively low-cost method for single-cell transcriptomics in the human gut microbiome. 👇

Proud to share our single-cell transcriptomics approach for the microbiome by instrument-free split-pool barcoding - metaSPLiT, developed by the incredible @monochamussutor.bsky.social together with @gibbological.bsky.social, @cdiener.com, et al. at @isbscience.org

The 2025–26 school year may be over, but ISB Education hasn't slowed down. This spring & summer, our team expanded teacher professional learning, finalized new classroom resources, welcomed district STEM leaders to ISB, and launched another summer of student research. isbscience.org/news/educati...

Dear microbiome enthusiasts: I'm excited to be moving my lab to New York University this fall (& the NYU Institute for Engineering Health); with joint-appointment @isbscience.org I'm hiring a postdoc @ NYU to look at diet-driven evolution in the gut: apply.interfolio.com/189980 Please share! 🦠🤓

Read ISB's news release here: isbscience.org/news/press-r...

160+ guests joined @isbscience.org for An Evening of Laurels, celebrating @nobelprize.org laureate Dr. Mary Brunkow and the future of women in science. This short video captures highlights. Full recap and video: isbscience.org/news/women-i... @lostwomenofsci.bsky.social

"There is a profound curiosity." Last week, Lost Women of Science co-founder Katie Hafner joined Nobel laureate Mary Brunkow for a conversation about overlooked women scientists, mentorship, visibility, and creating opportunities for future generations. Watch: isbscience.org/news/women-i...

"Leave yourself open to opportunities when they arise. Be willing to take a risk and say yes to the unknown." @nobelprize.org laureate Mary Brunkow delivered the commencement address at the UW's 151st Commencement ceremony. Her remarks start around the 2-hour mark: www.youtube.com/watch?v=Uhoc...

As graduates push back on AI-focused commencement speeches, UW's Nobel Prize-winning commencement speaker is taking a different approach. @geekwire.com talks with @isbscience.org scientist Mary Brunkow ahead of Saturday's commencement address. www.geekwire.com/2026/as-grad...

Join us June 11 for a free virtual conversation with Katie Hafner, co-founder of @lostwomenofsci.bsky.social , and Nobel laureate Dr. Mary Brunkow. We'll explore the stories behind LWoS, scientific recognition & visibility, & the evolving role of women in science. isbscience.zoom.us/webinar/regi...

Our latest preprint, led by PhD student Jacob Cavon, is online: "Multivariate determinants of wearable-measured sleep quality across a large observational cohort: roles of physical activity, gut microbiome, blood analytes, and lifestyle factors." 🦠😴🏃⚕️ www.medrxiv.org/content/10.6... 🧵...

Researchers at @isbscience.org have developed a powerful new platform that can identify and deeply profile antigen-specific #CD4+ #TCells at unprecedented scale and resolution. Learn more from Drs. Rongyu Zhang and Jim Heath: https://bit.ly/3PrpSYt

A global multiomics human diversity study is helping researchers better understand how genetics, environment, lifestyle, and the microbiome interact to shape human health. @cellpress.bsky.social isbscience.org/news/health/...

NEW: @isbscience.org researchers developed a high-throughput platform to identify and profile antigen-specific CD4+ T cells at single-cell resolution. Published in Nature Communications, the work could help advance vaccine research and next-gen cancer immunotherapies. isbscience.org/news/cancer/...

Meet Laasya Cheruvu! Laasya is a junior at Bothell HS in WA who participated in our System Thinkers in STEM Ambassadorship. Check out Laasya’s STiSA project: see.isbscience.org/projects/laa... #STEMsystemsthinkers @isbscience.org

Thank you for your visit, Congresswoman Jayapal! @jayapal.house.gov

Antibiotic resistance in #tuberculosis may start before treatment begins. New research shows oxidative stress from the host immune system can prime bacteria to evolve resistance more quickly — changing how scientists understand the emergence of drug resistance. @nitinbaliga.bsky.social

A new study reveals 1,700+ protein-like molecules hiding in the human genome — expanding what we thought we knew about the proteome. These newly identified “peptideins” could play roles in cancer, immunotherapy, and disease. isbscience.org/news/chronic... @nature.com

It's worth it! Give it a watch! @alicekane.bsky.social

What helps us stay healthier as we age? @alicekane.bsky.social shared how her lab at @isbscience.org is studying #frailty and #aging — and how #exercise, #sleep, financial stability, and life satisfaction may help build #resilience. Recap and full video: isbscience.org/news/isb-eve...

Excited to see this work out! 💩🍨🐁 "If you give a mouse a poopsicle: a novel fecal microbiota transplant method for exploring the role of the gut microbiome in stress-related outcomes in mice" www.frontiersin.org/journals/imm... @isbscience.org @uwnews.uw.edu 🧵...

If you missed this week’s Research Roundtable, the recording is now available. ISB’s @alicekane.bsky.social explores the biology of aging — including frailty, menopause, and what shapes long-term health. Watch here: isbscience.org/news/isb-eve...

💊 An @isbscience.org study reveals a surprising twist: the same drugs designed to stop cancer can also trigger a stress response that helps some cells survive. Researchers showed that melanoma cells can rapidly shift into a temporary, drug-tolerant state to escape treatment: https://bit.ly/3OYKJSB

MolES’ Scientific Exchange sparks microbial engineering collaborations www.moles.washington.edu/moles-scient... @flash-point.bsky.social @isbscience.org @uwgenome.bsky.social @uwbioe.bsky.social @basicsci.fredhutch.org @uwmnewsroom.bsky.social

Today’s the day. Join us at noon PT to watch @alicekane.bsky.social discuss new insights into frailty and women’s health across the menopause transition, shedding light on the biological drivers of aging. This event is free and virtual. Register now! isbscience.zoom.us/webinar/regi...

Aging isn’t a single, uniform process. Join us April 21 for a Research Roundtable with @alicekane.bsky.social, exploring frailty and women’s health across the menopause transition — and what it reveals about how the body ages. Free, virtual — register today! isbscience.zoom.us/webinar/regi...

What if cancer doesn’t wait for mutations to survive treatment? New work published in Nature Communications shows melanoma cells can rapidly adapt to targeted therapy — shifting into a temporary, drug-tolerant state driven by stress. @natureportfolio.nature.com isbscience.org/news/cancer/...

A new study co-led by ISB and published in the journal Cell Reports Medicine reveals how a rare lung cancer can shift between cell types, pass through hybrid states, and build distinct tumor “neighborhoods” that may help it evade detection and resist treatment.

What if some lung cancers don’t stay in one state? Research co-led by @isbscience.org shows rare mixed lung tumors can shift identity as they evolve, creating hybrid cell states & immune-protected regions that may help them resist treatment. @cp-cellrepmed.bsky.social isbscience.org/news/cancer/...

This winter, ISB Education engaged thousands of learners through community events, student field trips, and STEM programs. isbscience.org/news/educati... @systemsed.bsky.social @nitinbaliga.bsky.social @claudiamcl.bsky.social

BrainFest at the Pacific Science Center rocked! 🧠 ⚡️ 🤘 Thank you to all the young scientists who joined our cerebral celebration and all the volunteers, including from our partners at @uwmedicine.bsky.social, UW, @isbscience.org, and many more! #BrainAwarenessWeek #brainfest

Today is National Science Appreciation Day. At ISB, that means advancing research to better understand — and ultimately improve — human health. From cancer & the microbiome to multi-omics & data-driven biology, our teams are working across disciplines to tackle complex problems. isbscience.org

Whitney Gibb’s #LongCOVID journey shows how profoundly the condition can affect daily life — even when standard tests appear normal. Her story highlights both the lived experience of brain fog & fatigue, & the scientific challenges researchers are working to solve. 🔗 isbscience.org/news/infecti...