J. Craig Venter Institute

J. Craig Venter Institute

@jcvi.org

Not-for-profit research institute advancing the science of genomics through bold innovations to improve human health and environmental sustainability. Learn more at https://www.jcvi.org.

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Two days honoring the life and science of J. Craig Venter, Ph.D. Oct 13–14 · San Diego · The US Grant Hotel Nearly 30 speakers on the race to sequence the human genome, the first synthetic cell, xenotransplantation, and the Sorcerer II expedition. Agenda ↓ www.jcvi.org/events/j-cra... 🧪🧬

jcvi.orgJ. Craig Venter Memorial Symposium & GalaWe invite you to a two-day symposium, October 13–14, 2026, that will gather leading minds from across the scientific community. The symposium...

Researchers at the J. Craig Venter Institute and collaborators found molecular evidence of a marine-derived community of microscopic eukaryotes living near Blood Falls, a striking iron-rich outflow emerging from beneath Taylor Glacier.

The findings suggest that remnants of ancient seawater ecosystems may still persist beneath the ice today. Published in @natgeosci.nature.com, the study sheds new light on how life survives in extreme environments & offers clues about Antarctica's environmental history. www.jcvi.org/media-center...

jcvi.orgAncient marine life may be hiding in Antarctica’s Blood FallsLA JOLLA, California—August 3, 2026—Blood Falls has long been one of Antarctica’s strangest landmarks: a red-stained outflow that spills from...

JCVI has been awarded a $200,000 Emily Beazley Kures for Kids Fund St. Baldrick’s Research Grant to support Nan Zhu, Ph.D.'s research into a novel dual-action therapy for MLL-rearranged childhood leukemias—

In the final legs of their Tonga expedition, Dr. Garza and the eXXpedition crew partnered with local communities to better understand the sources of marine plastic pollution affecting their islands.

The expedition’s first stop combined field surveys, scientific outreach, and analytical sampling to establish a baseline understanding of plastic pollution in Tonga before continuing its broader investigation into how plastic waste moves from land to sea.

New study from JCVI's @taeseokmoon.bsky.social: DNA carrying antibiotic-resistance genes can remain functional after common decontamination steps like bleach & autoclaving. Findings can help refine biosafety guidance & disposal practices.🧪@cp-cellrepmethods.bsky.social www.jcvi.org/media-center...

jcvi.orgStudy finds DNA carrying antibiotic resistance genes can remain functional after common lab decontamination stepsLa Jolla, California—May 8, 2026—A new study in the journal Cell Reports Methods raises a practical biosafety question that begins after an...

JCVI scientist Erin Garza is joining the Global All-Women Sailing Expedition to study how plastic pollution moves from land to sea in Tonga. During Leg 3, she will lead waters, land, and & air sampling to support research on microplastics and environmental impact. www.jcvi.org/blog/trackin...

jcvi.orgTracking plastic pollution from source to sea: Tongatapu to Vava’UThis spring, I’ll be heading back to sea as part of the Global All‑Women Sailing Expedition, a ten‑leg research initiative sponsored and led by...

J. Craig Venter Institute reposted

His leadership and vision reshaped genomics and helped ignite synthetic biology. We will honor his legacy by continuing the mission he built—advancing genomic science, championing the public investments that make discovery possible, and partnering broadly to turn knowledge into impact.

Registration is closing soon for our upcoming BV-BRC workshop at Argonne National Laboratory! 🧪 If you’re planning to join us, now is the time to complete your visitor registration to ensure access to the site. This is a required step for all attendees.

The international team is led by JCVI's Marcelo Freire and FOB/USP's Paulo Sérgio da Silva Santos, with Mailon Cury Carneiro, a former visiting PhD student in Freire's lab and now a visiting scientist affiliated with the institute.

Ongoing studies from this collaboration are now investigating the underlying microbial and immunological mechanisms, with promising results. Further publications are expected soon.

Using a cysteine challenge test, the team revealed that most participants harbored latent halitosis undetectable under standard conditions and even individuals without clinically confirmed bad breath reported significant emotional distress.

The research looks at clinical and psychosocial aspects of halitosis, and how volatile sulfur compounds—especially methyl mercaptan—correlate with quality of life. Understanding these mechanism can inform better diagnostics and treatments.

Last May we announced we were moving to new west coast headquarters at IQHQ's state-of-the-art Research and Development District (RaDD) in downtown San Diego. Construction has been rapidly proceeding and we are counting down the months until we move into our fabulous new space this summer!

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Our move to the RaDD campus marks an exciting new chapter for JCVI. We’re looking forward to being part of downtown San Diegos’s growth, and we know our new home base will be an excellent environment for our researchers to continue to advance critical genomic science.

Last May we announced we were moving to new west coast headquarters at IQHQ's state-of-the-art Research and Development District (RaDD) in downtown San Diego. Construction has been rapidly proceeding and we are counting down the months until we move into our fabulous new space this summer!

This multi-use campus spans approximately 1.7 million square feet across six city blocks on San Diego's downtown waterfront, integrating advanced laboratory and office space with modern infrastructure.

JCVI Assistant Professor, Erin Garza, PhD is currently aboard R/V Sally Ride off the coast of California as part of a larger expedition to study the region's California Current, which is an important upwelling system and one of the most productive ocean areas in the world. 🧪

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The microbiome of plastics mainly consists of microbes that like to grow attached to substrates, so she is hopeful to find plastic degraders among these samples. She will be taking air and water samples for microplastic count along the voyage.

JCVI Assistant Professor, Erin Garza, PhD is currently aboard R/V Sally Ride off the coast of California as part of a larger expedition to study the region's California Current, which is an important upwelling system and one of the most productive ocean areas in the world. 🧪

Studying these systems helps us better understand how upwellings support marine food webs and contribute to nutrient cycling. These areas are also vulnerable to climate change and need to be regularly monitored.

Led by the Aluwihare lab of Scripps Institution of Oceanography and chief scientist, Dr. Benjamin Granzow, the ship will be collecting sinking, suspended, and dissolved organic matter for genomic, metabolomic, and proteomic analysis.

Early bird registration for the 2nd SynBYSS Conference in Barcelona on June 8–11, 2026 is ending soon! Register now to ensure a spot. SynBYSS coincides with a visit by Pope Leo XIV honoring the 100th anniversary of architect Antoni Gaudí's death, so hotels may fill quickly. www.jcvi.org/synbyss

jcvi.orgSynBYSSThe International SynBYSS Conference is focused on bringing together the synthetic biology community with the explicit goal of developing young...

Our team contributed key experimental data, including engineered mutants, growth rates, and phenotypic measurements that helped ground the model in biological reality.

J. Craig Venter Institute reposted

Our collaborative work is out in Environmental Science & Technology, a high-impact @acs.org journal. Thanks to Kim Parker for her leadership & researchers in her & my labs for tireless efforts in this challenging project funded by NSF, US EPA & USDA @jcvi.org pubs.acs.org/doi/10.1021/...

pubs.acs.orgGenetic Markers Remain Detectable in Genetically Engineered Microbes Biocontained with a CRISPR Kill SwitchBiocontainment strategies, such as kill switches, have been developed to avoid the unintended proliferation of genetically engineered microbes (GEMs) intended for open-release environmental applications. However, the presence of GEM DNA after successful biocontainment presents new environmental risks and challenges for monitoring. In this study, we investigated whether biocontainment using a CRISPR-Cas9 kill switch, which causes double-strand breaks in target genes essential for GEM growth, could resolve this challenge in a model Escherichia coli GEM. Surprisingly, the escape rates of the GEM as determined by CRISPR-targeted gene abundances were as high as 10–1.6 to 10–1.0 in LB media, despite the escape rates measured by colony forming units (cfu) being only 10–6.2 under the same condition. This discrepancy suggested that the CRISPR-Cas9 kill switch prevents colony growth while still leaving a large fraction of target genes intact for detection by molecular methods. Within 1 h after biocontainment, these target genes remained predominantly inside an intact cell membrane and were resistant to degradation by DNase, though degradation was observed in river water over multiple days. Overall, a detailed understanding of the impact of the biocontainment mechanism on both the GEM and its DNA is needed to minimize unintended environmental risks.

Together, the panelists guided the audience through the current scientific landscape with thoughtful discussion of the ethical questions that will shape how science influences society and our future.

J. Craig Venter Institute reposted

#SynBYSS conference is scheduled on Jun 8-11, 2026 in Barcelona. Given the 100-year celebration of Architect Gaudi in Barcelona, we suggest early booking of hotels. Details can be found: www.jcvi.org/events/synbyss (speakers, abstract submission & registration) @jcvi.org @marcguellc.bsky.social

jcvi.orgSynBYSSThe International SynBYSS Conference is focused on bringing together the synthetic biology community with the explicit goal of developing young...

J. Craig Venter Institute reposted