Jeremie Roux (@jrxlab.bsky.social)

Jeremie Roux

@jrxlab.bsky.social

single-cell response dynamics

6 followers 27 following5 posts

Jeremie Roux reposted

CNRS Biologie

@cnrsbiologie.bsky.social

25 Aug

#ResultatScientifique🔎| L'efficacité d'un médicament dépend de la variabilité naturelle des états moléculaires des cellules au moment du traitement ✍️ @jrxlab.bsky.social 👋 @cnrscotedazur.bsky.social @insermpacacorse.bsky.social @univcotedazur.bsky.social buff.ly/ILNz5Ag

insb.cnrs.frL’efficacité d’un médicament dépend de l’état moléculaire de chaque cellule au moment du traitementÀ une d

Jeremie Roux

@jrxlab.bsky.social

1 Oct 2025

Our latest paper just came out in Molecular Systems Biology ! Transition between cell states of sensitivity reveals molecular vulnerability of drug-tolerant cells @molsystbiol.org www.embopress.org/doi/full/10....

This study carried out at @univcotedazur.bsky.social, IPMC CNRS - University Nice Sophia Antipolis, Centre Inria d'Université Côte d'Azur, @cnrsbiologie.bsky.social, @cnrscotedazur.bsky.social, @cnrs.fr.

Jeremie Roux

@jrxlab.bsky.social

1 Oct 2025

With the support of: @canceropolesud.bsky.social, Labex Signalife, @ihu-respirera.bsky.social, Institut national du cancer, CNRS Innovation and Région Sud - Provence-Alpes-Côte d'Azur !

Cells continuously switch between states of sensitivity: cell-states of drug-sensitivity coexist in a clonal population. The sub-population that resists apoptotic treatments will transiently exhibit features of sensitivity to necroptotic treatments, suggesting an optimal treatment sequence.

Jeremie Roux

@jrxlab.bsky.social

1 Oct 2025

Big thanks to Ludovic Peyre, Marielle Péré, Mickael Meyer, Benjamin Bian, Marina Moureau-Barbato, Walid Djema, @bernard-mari.bsky.social and Georges Vassaux !

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