Katherine Stefanski

dlvr.itPharmacological tools to modulate ordered membrane domains and order-dependent protein functionCommunications Chemistry, Published online: 08 January 2026; doi:10.1038/s42004-025-01874-8Although ordered membrane nanodomains, also known as lipid rafts, have many proposed cellular functions, pharmacological tools to modulate protein affinity for rafts and to manipulate raft formation are currently lacking. Here, the authors screened 24,000 small molecules for compounds that impact the raft affinity of a known raft-preferring model protein, peripheral myelin protein 22 (PMP22), in giant plasma membrane vesicles, identifying three chemically distinct tools for modulating raft formation in a protein-independent manner by altering lipid–lipid interactions and membrane fluidity in biophysical experiments and in living cells.

11 Jan

Happy to share this work is finally out!

Communications Chemistry@commschem.nature.com

Just out: Pharmacological tools to modulate ordered membrane domains and order-dependent protein function

Katherine Stefanski reposted

Cory Booker

@corybooker.com

2 Apr 2025

I may be tired and a little hoarse, but as I said again and again on the Senate floor, this is a moment where we cannot afford to be silent, when we must speak up.

grc.org2025 Membrane Protein Folding (GRS) Seminar GRCThe 2025 Gordon Research Seminar on Membrane Protein Folding (GRS) will be held in Castelldefels, Barcelona Spain. Apply today to reserve your spot.

Calling all membrane/membrane protein folks! Join us this summer in Barcelona for the Membrane Protein Folding Gordon Conference and Seminar. GRS chaired by @justmwest.bsky.social and myself! We are soliticiting abstracts from trainees for talks! Deadline - April 6. www.grc.org/membrane-pro...

Additionally, this community is unbelievably supportive and exactly what we all need right now.

open.spotify.comThe Tortured Proteins DepartmentPodcast · Stephanie Wankowicz · A deep dive into scientific discovery and the process of doing science, hosted by Stephanie Wankowicz and James Fraser.

We know its hard to commit to registration fees in these uncertain times. Selected speakers will recieve a registration waiver to the GRS!

Katherine Stefanski reposted

James Fraser

@fraserlab.com

16 Mar 2025

Since @stephanieaw.bsky.social left the lab to start her group at Vanderbilt, we've been talking regularly on the ups and downs of academic science. We started recording... The Tortured Proteins Department open.spotify.com/show/10PHVou... (science with a small dose of running and Taylor Swift)

Katherine Stefanski reposted

Colette Delawalla, PhD

@cdelawalla.bsky.social

8 Mar 2025

Thank you, all. @standupforscience.bsky.social @jpflores.bsky.social @samschuelstein.bsky.social @emmalovesscience.bsky.social @leslie-bern.bsky.social #standupforscience2025 #scienceforall

Katherine Stefanski reposted

WPLN News - Nashville Public Radio

@wpln.bsky.social

8 Mar 2025

Amid a federal government crackdown on academic and research institutions, WPLN health reporter @catherinejsweeney.bsky.social says hundreds of protesters filled the Tennessee State Capitol steps in downtown Nashville on Friday.

wpln.orgHundreds gather to protest cuts to medical research funding, crackdowns on DEIAmid a federal government crackdown on academic and research institutions, hundreds of protesters filled the Capitol steps in downtown Nashville. Among several other initiatives, the Trump Administrat...