Helen Rowe @RoweLab
Helen Rowe @RoweLab
@labrowe.bsky.social
Discovery science driven. Hope to contribute to translating discoveries into new medicines.
956 followers257 following13 posts
* Hot off the press from the Rowe Lab 📢 * : For in depth insight on LINE-1 jumping genes, from their regulation to their multifaceted roles in cancer immunity, read Holly Jefferson's review here: www.mdpi.com/1999-4915/18...
doi: doi.org/10.1038/s414... 📣 Our study is now out in Nature Communications detailing that the type I interferon pathway is suppressed by HUSH in early human development: Its complete epigenetic lockdown!! Incredible work from James Holt 📣 😎
How do pluripotent stem cells resist harmful interferon responses to safeguard development? Through total epigenetic lockdown of ligands, sensors and effectors of IFN-I. In our preprint, James Holt shares his PhD discoveries on the ground state of immune evasion 😊: www.biorxiv.org/cgi/content/...
What's on the horizon of cancer immunotherapies? Understanding epigenetic checkpoints, we say 😊: news.cancerresearchuk.org/2025/09/11/l...
Looking forward to this meeting this week: Transposable elements are controlling elements in health and disease, genetics.org.uk/events/the-r... organised by the Genetics Society 😊
Helen Rowe @RoweLab reposted
How do tumours evade destruction by the immune system? We are recruiting two postdocs (wet lab/dry lab) to shed light on epigenetic checkpoints of anti-tumour immunity in lung cancers, funded by CRUK. Please get in touch to find out more! www.qmul.ac.uk/jobs/vacanci... www.qmul.ac.uk/jobs/vacanci...
I am honoured to receive a Programme Foundation Award from Cancer Research UK on epigenetic regulation of immune evasion in non-small cell lung cancer. Thanks to my co-investigators, collaborators, mentors, lab & @qmulepigenetics.bsky.social for supporting this exciting translational project.
Helen Rowe @RoweLab reposted
Please join us for the @QMULepigenetics seminar by Kristian Helin from @icr_london 11th Jan. 15.30GMT. venue: Derek Willoughby Lecture Theatre, at our Charterhouse Square campus. or online link at qmulepigenetics.com/webinars
Helen Rowe @RoweLab reposted
Enlightening review from @KathleenHBurns lab: genesdev.cshlp.org/content/37/2...: LINE-1 activity and jumping contributes to genetic instability in cancer and understanding LINE-1 deregulation could lead to new therapeutic opportunities. A must-read.
Elegant preprint identifying mutually exclusive targeting of HUSH1 vs. HUSH2 chromatin complexes for silencing dangerous LINE-1 elements in the human genome: www.biorxiv.org/content/10.1...
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