Lara Goscé

Our new paper in @nathealth.nature.com shows that population-level #TB interventions are likely to have more meaningful impact on disease burden than interventions that only reach routinely diagnosed individuals or their households. www.nature.com/articles/s44... 1/7

Poverty is a major driver of TB.Conditional cash transfers combined with counselling improve pre-treatment loss to follow-up.In this economic analysis our modelling projections show that this intervention is cost-effective and can reduce incidence and mortality. www.sciencedirect.com/science/arti...

@lshtm-tbmod.bsky.social is offering multiple PhD opportunities through MRC LID, deadline 14 Jan. More details: mrc-lid.lshtm.ac.uk/applicants/ Projects include #1 TB & screening #2 TB & climate change #3 TB & vaccines #4 TB & influenza #5 TB & prevention @cmmid-lshtm.bsky.social @lshtm.bsky.social

Join us 📆 9 Dec ⏰ 12.45 @tb-lshtm.bsky.social seminar Free & Open to all @kchorton.bsky.social @richardwhite321.bsky.social @reinhouben.bsky.social @dopapus.bsky.social @laragosce.bsky.social @danieljgrint.bsky.social tinyurl.com/2s4y3jcd

Another successful "Intro to TB Modelling" course in Copenhagen at #WLHC2025. Over 70 joined to learn about TB modelling! Followed by the now-traditional TB Modelling and Analysis Consortium social, which was also very well-attended and a lot of fun.

Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.thelancet.com/journals/lan...

“Wow, I saw in the last GTB report undernutrition is much less important for TB than we previously thought” I hear you say… Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition – see our latest comment here: www.thelancet.com/journals/lan...

When fluoroquinolone resistance status is unknown, empirical use of BPaLM (adding moxifloxacin to BPaL) is cost-effective as a replacement for BPaL even with high fluoroquinolone resistance levels! 🦠💊 doi.org/10.1371/jour...

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492

In a new preprint (NOT PEER REVIEWED) we continue to explore the challenge of overtreatment in community screening. It seems the benefits of TB treatment far outweigh the harms, especially once we accept that sputum culture is not perfect. Important food for thought. www.medrxiv.org/content/10.1...

At a time when global resources for #TB research, development, prevention, and care are limited, which interventions should be prioritised in high burden settings? 📢 Our new pre-print compares the impact, cost, and cost-effectiveness of 9 TB interventions in 3 countries. 1/n bit.ly/3V3vXth

The State Department's decision to impose sanctions on Francesca Albanese, the U.N. special rapporteur for the West Bank and Gaza, follows an unsuccessful campaign to force her removal.

Secretary of State Marco Rubio has imposed sanctions on Francesca Albanese, the U.N. special rapporteur on the occupied Palestinian territory. Albanese says the move is an effort to “distract” from the genocide in Gaza.

New systematic review led by @hannahrickman.bsky.social shows annual risk of Mycobacterium #tuberculosis conversion in men and women diverges during adolescence and remains higher among men throughout adulthood. www.thelancet.com/journals/lan...

In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials. doi.org/10.1016/S221... @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

A study in the Lancet recently looked at the cumulative impact of reductions in American aid. It found that, by 2040, 8 million more children will die before their fifth birthday. b-gat.es/44wCCQO

The facts are simple and devastating: Aid cuts have already cost lives, and the number of deaths will continue to rise. Here’s the evidence. ​

LSHTM's Director writes to UK Government about #Gaza public health catastrophe Professor Liam Smeeth's letter to the Prime Minister & Foreign Secretary urges action to prevent a greater #PublicHealth disaster: 👉 www.lshtm.ac.uk/newsevents/n...

Can you believe it’s already been 25 years!? Come join us on 20 June 2025 at 4pm UK time to celebrate the 25th anniversary of the Introduction to #Infectious Disease #Modelling course delivered by @lshtm.bsky.social and @ukhsa.bsky.social! More info 👉 www.lshtm.ac.uk/newsevents/e...

TB & climate change: @who.int report out now, building on an analytical framework we developed to explore the intersections and implications for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.who.int/publications...

Amid all the bad news in Global Health, perhaps some good news? A first analysis on the risk of false positive diagnoses in community-screening for tuberculosis using Xpert shows our clinic-based data is likely (very) wrong and overestimates false positives by >80%: tinyurl.com/yfecute9.

Postdoc (London, UK) Position available in the world-leading tuberculosis (TB) Modelling group at LSHTM with @raclark18.bsky.social‬ @richardwhite321.bsky.social at LSHTM @lshtm-tbmod.bsky.social More details: http://iddjobs.org/jobs/2314

Climate-driven migration and displacement and their potential impact on TB in Latin America gh.bmj.com/content/10/4... @cfmcquaid.bsky.social @reinhouben.bsky.social @lshtm-tbmod.bsky.social

Climate change is likely to exacerbate determinants which drive TB, the world’s leading infectious disease killer. Commissioned by WHO, we developed an analytical framework outlining potential causal relationships between climate change and TB: medrxiv.org/cgi/content/... @lshtm.bsky.social @who.int

Three PhD opportunities in modelling at @lshtm.bsky.social and @ukhsa.bsky.social on: Homelessness/Housing and TB: shorturl.at/FJ57W EBV and cancers in the UK: shorturl.at/IRHJk Climate change and TB: shorturl.at/R7f50

PhD position (London, UK) Quantify the effects of climate change on TB with @cfmcquaid.bsky.social @reinhouben.bsky.social @laragosce.bsky.social at @cmmid-lshtm.bsky.social @tb-lshtm.bsky.social @lshtm.bsky.social More details: http://iddjobs.org/jobs/2253

New PhD opportunity at LSHTM @lshtm.bsky.social @cmmid-lshtm.bsky.social and UKHSA www.lshtm.ac.uk/study/fees-a...

1/ 📢 In our new PREPRINT - tinyurl.com/2pmudzrk - we evaluate how symptom-agnostic, population-wide screening interventions could significantly reduce the TB burden in Viet Nam. These require a substantial front-loaded investment but yield lasting cost savings. 🧵 #Tuberculosis #TBSky

Our ASCENT modelling paper on Digital Adherence Technologies (DAT) for TB treatment is now out in BMJ Global Health gh.bmj.com/content/9/12... DATs may have limited epidemiological impact but can reduce costs and have important budgetary implications. @cfmcquaid.bsky.social @lshtm-tbmod.bsky.social

Reflecting on this year’s #TB #UnionConf2024 and am so inspired by the brilliant minds and groundbreaking research being done to combat this global health threat. Special shoutout to the TB Modelling Group @lshtm.bsky.social 🫁