Maillard Lab

Maillard Lab

@maillardlab.bsky.social

49 followers145 following3 posts

Maillard Lab
@maillardlab.bsky.social

Delighted to share a new paper from my lab in Nature Communications ! 🎉 Nodamura virus B2 enhances self-amplifying RNA activity while preserving its immune-stimulating properties. Led by @rayusanda.bsky.social with equal contributions from Josephine Nemegeer and @jerryhoang.bsky.social 👇

nature.comTuning intracellular immunity by Nodamura virus B2 protein enhances self-amplifying RNA activity - Nature CommunicationsThis study shows that expressing the viral protein B2 in self-amplifying RNA overcomes innate antiviral defences, boosting transgene expression while preserving immune-stimulating properties.
Maillard Lab
@maillardlab.bsky.social

Congratulations to the organisers on a fantastic EMBO Workshop in Leiden and now this excellent report in Nature Immunology. Thank you for the mention of our talk on improving self-amplifying mRNA vaccine efficiency, it was a pleasure to present at such an exciting event. Looking forward to 2028!

EMBO@embo.org

The EMBO Workshop "#PathogenImmunity and Signaling" that took place in Leiden, the Netherlands this year, brought together 175 participants from 25 countries. 🧪 A report in Nature Immunology summarizes the meeting: https://www.nature.com/articles/s41590-026-02657-6

nature.comNew frontiers in pathogen immunity - Nature ImmunologyThe EMBO workshop ‘Pathogen Immunity and Signaling’ was held from 8 to 11 June 2026 in Leiden, the Netherlands, bringing together 175 participants from 25 countries to discuss the latest advances in antimicrobial immune defense.
Maillard Lab
@maillardlab.bsky.social

Better late than never, I have only recently joined Bluesky! Delighted that this study is now published in Nature Communications ! 🎉 Led by James Holt, a collaboration between the lab of Prof. Helen Rowe and mine, revealing epigenetic control of innate immunity in early development. 👇

Helen Rowe @RoweLab@labrowe.bsky.social

‪doi: doi.org/10.1038/s414... 📣 Our study is now out in Nature Communications detailing that the type I interferon pathway is suppressed by HUSH in early human development: Its complete epigenetic lockdown!! Incredible work from James Holt 📣 😎

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