Marco Hein

Time to share our organelle proteome paper out in @cellcellpress.bsky.social: doi.org/nzwz We created a spatial map of human cells using organelle immunoprecipitation at scale. Locate your fav protein among the 7,600 we mapped across 19 subcellular compartments: organelles.sf.czbiohub.org/ 1/3 🧪

Just did some number crunching using latest (Oct 1) ECMWF seasonal data, and I must say that I've never seen such high predictive confidence in a very wet California winter. This is a truly extraordinary forecast amid a record-strength El Niño event. [Thread: please read to end.]

Influenza A/H1N1 positivity has already pulled even with SARS-CoV-2 in Biofire's surveillance in US, very early in the season. A/H1N1 never passed covid last winter, and in 2025-25 it didn't pass covid until mid-December. Not a good year to put off your flu shot!

Looking boldly into the future while keeping the lessons of history in mind. Celebrating the opening of @meduniwien.ac.at‘s two new institutes: the Center for Translational Medicine and the Eric Kandel Institute - Center for Precision Medicine, together with my @maxperutzlabs.ac.at colleagues.

Super excited to share my postdoctoral work at @imbavienna.bsky.social @viennabiocenter.bsky.social - We discovered that some retrotransposons, or "jumping genes" 🧬, are able to spread from cell to cell via a new viral infectivity route. A short thread: 🧵👇 (1/7)

Very proud of Leon for his DOC fellowship!

One frame. Many voices. 🔬 Kavya Shetty, PhD student in the Hein lab, brings an important message to our #WomenInScience series: diverse role models matter, especially for the scientists who come next 🤝

Very happy to be named “researcher of the month” at @meduniwien.ac.at

1/ out in @science.org! We found a new asymmetry in large-scale chromosome structure: sister chromatids are shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! A close collaboration w/ @gerlichlab.bsky.social , led by @flaviacorsi.bsky.social www.science.org/doi/10.1126/...

Given rising interest in the rapidly strengthening El Niño event in the tropical Pacific Ocean, I've created a one-page fact sheet succinctly describing what El Niño is, this year's (remarkable) forecast, and potential impacts from California to global scales. [Thread]

I am hiring a computational postdoctoral fellow or bioinformatics scientist! Please apply here if interested, or share with anyone who may be. This position will be following up on our work studying the virus-host conflict. Reposts appreciated! aithyra.onlyfy.jobs/en/job/v2gwu...

Happy to share the first preprint out of the Nomburg lab! Many aspects of cellular immunity are shared across the tree of life. Here, we show that some of these conserved aspects of cellular immunity are mirrored by conserved effectors of immune antagonism. Thread below! 1/15

How do you indicate in a slide deck that an image is AI-generated (and not real data or human-made artwork) in a clear yet unobtrusive way? Today I saw a great solution: a small astroid (the geometric shape, not an asteroid), similar to the Gemini logo. Simple, subtle, and easily recognizable.

This is so cool live.infrared.city

Liebe Autofahrer:innen, in Straßen wie diesen könnt und dürft ihr nicht überholen, weil der Mindestabstand (1,5 Meter) nicht eingehalten werden kann. Also entspannt euch, nehmt den Fuß vom Gas und fahrt brav hinterher. Und zwar nicht nur am #Weltfahrradtag. #WorldBicycleDay

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

The 2026 West Nile virus season is underway. Our first weekly seasonal surveillance report is now available. As of 27 May 2026, one human case of West Nile virus infection has been reported in Europe, from North Macedonia. wnv-weekly.ecdc.europa.eu #IDsky #EpiSky #PublicHealth #WestNileVirus

www.nature.com/articles/d41...

TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data. @sholtodavid.bsky.social @johanduchene.bsky.social reeserichardson.blog/2026/05/28/h...

Around 21,000 demonstrators gathered in Vienna today to protest the budget cuts for public universities #UnisRetten

Big demonstration planned for tomorrow to protest the Austrian government’s proposed budget cuts for public universities #UnisRetten

How do sperm and egg fuse? Surprisingly, we still don’t fully know… Our field has uncovered many pieces of the fertilization puzzle, but not how they fit together. We identify ✨ SPARK ✨ - a conserved sperm complex that couples sperm-egg binding to fusion. tinyurl.com/34cm4xat Read on! 🧵👇

#thermogate

Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR. We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets. Thread + link below.

The number of grant applications is rising sharply. Our capacity for their evaluation isn’t. ERC President Maria Leptin explains why stricter resubmission limits are being introduced for 2027 calls and what they mean for applicants. 🔗 link.europa.eu/xF7kjc

#Artemis II - We have the first image from yesterdays Lunar flyby captured by the crew on Orion EARTHSET. April 6, 2026. Humanity, from the other side. First photo from the far side of the Moon. Captured from Orion as Earth dips beyond the lunar horizon. 🚀🌕🌍

Our newest piece of lab equipment: Bio-Rad’s “Buffer C dispenser”, developed in cooperation with De’Longhi. A discreet bench-top device that won’t raise suspicions with the lab safety officers.

Exciting job offer: PhD Program Manager. Lead recruitment, support PhD candidates, and shape doctoral training at a top international life sciences campus. https://ow.ly/3YkN50YAuGM Institute of Molecular Biotechnology, Max Perutz Labs Vienna, IMP, Gregor Mendel Institute of Molecular Plant Biology

We are excited to share our new paper in Molecular Cell uncovering how the viral lncRNA RNA2.7 reshapes host cell biology! sciencedirect.com/science/authShare/S1097276526001565/20260324T143400Z/1?md5=16c84051c2f253c4665427f837a529d3&dgcid=author A thread 🧵

To better understand the ubiquitin-proteasome system, Suzanne Elsasser, Dan Finley, and the Human Proteostasis Consortium have systematically surveyed its components: www.biorxiv.org/content/10.6... I would encourage you to check out this valuable resource! @harvardcellbio.bsky.social

We are grateful to FWF for their support! It is a privilege to be part of this amazing team and work on this exciting truly collaborative project! Stay tuned!

I’m very happy to be part of our FWF “Emerging Fields” consortium! Together with @gekaragoz.bsky.social, @sebastianfalk.bsky.social and CCRI/CeMM/VetMedUni colleagues Eleni Tomazou, @dseruggia.bsky.social and @floriangrebien.bsky.social, we will study the ribosome code in pediatric cancers.

Fantastic news! 🙌 The Perutz is excited to welcome Danny Nedialkova as a new group leader starting this April! 🎉 She will strengthen the institute's research on the fundamental mechanisms that shape cellular physiology and disease ➡️ www.maxperutzlabs.ac.at/research/res...

Die Gesellschaft für Virologie begrüßt und unterstützt die Corona-Enquetekommissionen in den verschiedenen Parlamenten. Allerdings nehmen wir mit großer Sorge zur Kenntnis, dass darin auch wissenschaftlich nicht tragbare Behauptungen aufgestellt werden, wie kürzlich in der Kommission des … (1/2)

#Grippe-Welle in Österreich Zunahme der Influenzafälle - im Sentinelsystem überwiegen Nachweise von Influenza A Subtyp H3N2 und H1N1 (3:1) Weiterhin Aktivität von #SARS-CoV2 #Parainfluenza #saisonaleCoronaviren #Rhinoviren, sporadische RSV-Infektionen #ZentrumVirologie #MedUniWien

🎉 Congratulations to Max Kellner, former PhD student in the Penninger Lab, who was presented with the ÖGBMT Life Sciences PhD Award Austria. The award recognizes Kellner’s PhD research on how dangerous viruses emerge from natural reservoirs like bats. More: https://imba.science/3KiRYSN

Our Autumn call is now open with over 20+ fully funded positions in various disciplines in the life sciences. Interested? Check out our vacancies in computational biology, genomes & evolution and the exciting projects being offered here: ow.ly/aBgQ50WY1S2

I couldn’t be prouder of my team! Kavya and Sebastian both won DOC fellowships from the Austrian Academy of Sciences! Congratulations to all awardees!

We found a new asymmetry in the large-scale chromosome structure: sister chromatids are systematically shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! The work was led by Flavia Corsi, in close collaboration with the Daniel Gerlich lab. www.biorxiv.org/content/10.1... 1/

Join us at the Perutz, part of the Vienna Biocenter! Opening for a full professorship in Molecular Mechanisms of Disease 👇🏻 @maxperutzlabs.bsky.social @viennabiocenter.bsky.social @univie.ac.at

Exciting and rare opportunity to join the @maxperutzlabs.bsky.social and the @viennabiocenter.bsky.social as a Full Professor! www.nature.com/naturecareer...

Hello everyone! I am pleased to share information on the first ever Computational Structural Virology Symposium, conducted August 4th on zoom and highlighting work in this emerging field. You can register for this event here: forms.gle/CNiqskMwQEuV.... Please re-post!

If you love #viruses, #ribosomes, and genomic #darkmatter, this thread is for you!! 💫 We're excited to share our new publication developing Massively Parallel Ribosome Profiling (MPRP), which uncovered ~4,000 hidden proteins in ~700 viral genomes. www.science.org/doi/10.1126/...

Mass Spec xkcd.com/3094/

Hi 🦋 I’m thrilled to share that our #bat #organoid work has found a publishing home in Nature Immunology! These models provided unprecedented insight into antiviral immunity at epithelial surfaces of the Egyptian fruit bat 🦇 — a natural reservoir of Marburg virus 🦠 www.nature.com/articles/s41...

Innovative Forschung zur Entstehung & Kontrolle von #Metastasen ⤵️ Wir gratulieren @jwinkler.bsky.social von der #MedUniWien zur Auszeichnung der @oeaw.bsky.social mit dem Johann Wilhelm Ritter von Mannagetta-Preis!

🌟 Exciting #PhD Opportunity! Join my lab in beautiful #Vienna. We are studying tumor-immune interactions in #metastasis using #singlecell and #spatial omics! ⏰ Apply by 04/25 bit.ly/3l7WMhs more infos 👉 winklerlab.org

Aithyra is hiring! We are looking for multiple starting PIs in life sciences and AI/ML. We offer highly competitive packages and salaries among the highest in Europe. www.oeaw.ac.at/aithyra/news...

IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply now to our group leader position. The deadline is May 28. Link is below.

Dear @nature.com publishing group: We swallowed your $12k article processing charge, but the name of your new journal is too much…

1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬 But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯 Our new study reveals how retrotransposons invade the germline directly from somatic cells. www.biorxiv.org/content/10.1... A short thread 🧵👇