Maximiliano José Nigro

Maximiliano José Nigro

@maxnigro.bsky.social

Associate Professor NTNU #NigroLab; Diversity of neurons; cortical circuits; Biologist looking at neurons with birdwatcher's eyes https://nigrolab.com

1.1K followers764 following193 posts

The chiffchaff and the willow warbler are very hard to tell apart by shape or color. But listen to them! Many neurons look alike but they sing different songs for different purposes. At Forskningstorget we will explore the shapes, colors and songs of neurons #birdingthebrain #birding #neuroskyence

I am organizing an exhibition for Forskningstorget i Trondheim Birding the brain: how a birdwatcher studies neurons The plan is to give a birding tour of the brain to explore the shapes, colors and songs defining the extraordinary diversity of neurons. #Birding #neuroskyence

These are such important efforts by the IBL. I think its impact should be taken very seriously by neuroscientists (when they are in the lab or acting as reviewers) and by the publishers. “You either record an action potential or you do not” I don’t believe this is true for Neuropixels #neuroskyence

The Transmitter @thetransmitter.bsky.social

Differences stemmed from the way researchers defined concepts, to the algorithms they used to analyze the data, to the parameters they employed when implementing the algorithms, note @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence www.thetransmitter.org/reproducibil...

The IBL and recent papers applied strict criteria to define single units and showed how only about 10% of recorded data can be classified as single unit. But we still see bombastic claims of tens of thousands of “neurons” but no clear definition of selection criteria

The other branch along an evolving diversity of living things along Rue Geoffroy Saint-Hilaire that intersects Rue Buffon. Neurons as a probability distribution of properties shaped by developmental trajectory

Fantastic initiative at my Alma Mater University of Pavia by @ebrains.bsky.social School in Computational Neuroscience at the birthplace of Camillo Golgi! It is held in Piazza Botta, one of my favorite places in Pavia, close to the Golgi Institute and the Kosmos Museum! #neuroskyence

EBRAINS@ebrains.bsky.social

Apply for the EITN EBRAINS Fall School in Computational Neuroscience 2026! This 10-day course is designed for Master’s and PhD students and postdocs interested in advancing their knowledge in theoretical and computational neuroscience. Apply before 15 May: ebrains.eu/news-and-eve...

Maximiliano José Nigro reposted

The latest story from the #QuattrocoloLab fulfills a long time dream. Are #CajalRetzius cells important for the maturation of spatial navigation? It turns out that superficial pyramidal cells in CA1 care much more about CR cells postnatal presence that deep pyramidal cells.

bioRxiv Neuroscience@biorxiv-neursci.bsky.social

Spatial representation in CA1 superficial pyramidal cells is impaired after postnatal ablation of hippocampal Cajal Retzius cells https://www.biorxiv.org/content/10.64898/2026.03.24.711525v1

This is the most interesting paper I have read in a while. The organization of a neural system (nucleus, layer or whatever) does not matter for function as long as it contains the right cell types connected the right way. Thanks to @gquattrocolo.bsky.social for inviting me to her Journal Club

Sergi Roig Puiggros@sroig.bsky.social

I'm very excited to finally see this one out in @natneuro.nature.com ! It has been an incredible journey alongside extremely talented people! Thanks to everyone involved and enjoy the reading! 1/n www.nature.com/articles/s41...

I was not completely convinced of the «Position-independence» because the heterotopia seems to abide to rostrocaudal and mediolateral axes of cell types, connectivity and function as the cortex above. Hence the «organization-independence»

Maximiliano José Nigro reposted

Alfred Russel Wallace born OTD in 1823. He said he shared with Darwin “an intense interest in … the variety [of living things] that catches the eye of the observer even among those which are very much alike, but which are soon found to differ in several distinct characters.” 🌱🐋🧪 #HistSTM #EvoBio

Maximiliano José Nigro reposted

#QuattrocoloLab preprint out 👇! We explored changes in the proteome of hippocampal and dentate gyrus growth cones at early postnatal stages. We see that at P1 growth cones from the two subregions are very similar, but start to diverge from P3, with HP growth cones maturing earlier then DG ones.

bioRxiv Neuroscience@biorxiv-neursci.bsky.social

Proteomic profile of hippocampal growth cones through early postnatal development https://www.biorxiv.org/content/10.1101/2025.11.10.687591v1

In today’s lecture on microcircuit organization we will go through the classics from Penfield to Eccles and get to cell type specific optogenetics to dissect circuits for top down modulation of vision How neurons connect to compute with a reminder to their biophysical properties #neuroskyence

This looks like a promising step forward that improves quality rather than quantity Looking forward to dig in more!

This is very interesting. I am always terrified by extracellular recordings and Neuropixels have aggravated my anxiety. So I really appreciate studies like this. #neuroskyence

Amir Levi, Ph.D@amirlevi.bsky.social

Science of the day: Some spikes are just more positive than others, at least waveform-wise. Side science: interested in these positive units (Punits), check out this work by Shirly Someck www.nature.com/articles/s42... #Neuroscience #neuroskyence #punits #PositiveVibes

Basket cells, parvalbumin expressing or fast-spiking neurons, names that emphasize different properties of the same type. However they are not all the same, like these in the mouse barrel cortex: one has axon in its layer; the other sends axon to other layers Both are very beautiful #neuroskyence

Congratulations to @seanfw.bsky.social and team! Very interesting project leveraging large scale models to make sense of the even larger scale anatomical diversity across regions and species

Seán Froudist-Walsh@seanfw.bsky.social

Very grateful to be among an inspiring group of @ukri.org Future Leaders Fellows for the next 4-7 years. We will infuse brain anatomy into AI to study shared principles and important differences in cognition across species. www.ukri.org/news/ukri-an...

Our first steps into sensory processing is now online! Work spearheaded by Rejwan Salih from experiments by @prime5222.bsky.social and François Pauzin We were lucky to receive guidance from Davide Zoccolan on the analytical methods. #neuroskyence

bioRxiv Neuroscience@biorxiv-neursci.bsky.social

Tactile responses in the mouse perirhinal cortex show invariance to physical features of the stimulus https://www.biorxiv.org/content/10.1101/2025.08.15.670508v1

This week I am sharing the closing remarks from Wallace’s The Malay Archipelago. Here Wallace gives a critique of of Victorian society and what he learned living with the people he met in his travels #historyofscience #biogeography #neuroskyence