Michael Payne (@mjohnpayne.bsky.social)

Michael Payne

@mjohnpayne.bsky.social

Senior Research Fellow at University of Sydney. Microbial genomics, Bioinformatics and Python!

157 followers 343 following2 posts

@mjohnpayne.bsky.social

Finally a preprint for our tool DAMPA (Australiana included) that generates efficient probe panels for targeted metagenomics from pangenome graphs. Presented at ABPHM and ABACBS last year. www.medrxiv.org/content/10.6...

medrxiv.orgDAMPA - accelerated and simplified design of probe panels for targeted metagenomics using pangenome graphsTargeted metagenomics, where samples are enriched for multiple organisms of interest using oligonucleotide probes, is a highly efficient sequencing methodology that is becoming standard practice for g...

Michael Payne reposted

David Ma

@frostickle.bsky.social

25 Nov 2025

Great talk from Michael Payne at #ABACBS2025 on DAMPA - tool for designing probe panels for targeted metagenomics using pangenome graphs! Captures all diversity efficiently, uses fewer probes than competitors. Critical for syndromic surveillance! 🧬🔬 #Metagenomics

Michael Payne

@mjohnpayne.bsky.social

26 May 2025

Had a great time at #ABPHM where I presented our new tool github.com/Multipathoge.... DAMPA uses pangenome graphs to design targeted metagenomics probe panels that minimise probe number while retaining very high target coverage. Preprint coming soon!

github.comGitHub - MultipathogenGenomics/dampa: Dampa: Diversity Aware Metagenomic Panel AssignmentDampa: Diversity Aware Metagenomic Panel Assignment - MultipathogenGenomics/dampa

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