New England Biolabs

Molecular biologist Dr. Graham Hatfull has spent decades studying the molecular genetics of mycobacteria & their bacteriophages. In our latest podcast (https://nebiolabs.com/4zga4JF), he talks about his findings & the use of therapeutic phage to treat bacterial infections.

Earlier this month, a Nature Technology Feature included comments from NEB Production Scientist Emily Chen, Ph.D., on the benefits of cell-free protein synthesis for researchers! https://www.nature.com/articles/d41586-026-03136-6

Tomorrow afternoon is our #ASHG26 Industry Workshop! Learn more about “NEBNext Epigenomic Solutions Driving Multiomic Insight" and add it to your planner at: https://ashg.floq.live/event/ashg-2026/dailyprogramme?objectClass=timeslot&objectId=6a6acd2dd544faf2b0e975ee&type=detail

Tomorrow's the first day of the @geneticssociety.bsky.social 2026 Annual Meeting in Montreal! The NEB team is excited to talk genetics with attendees at booth 514 🦋 #ASHG26

Getting ready for #ASHG26? Don't forget to plan a visit to the NEB team at booth 514! @@geneticssociety.bsky.social

Last week's celebration of the Passion in Science Award winners was filled with activities and great conversations about passion for science! Thank you to our awardees for sharing their work with us and the world 🦋 Read about the event & awardees in The Local News: https://nebiolabs.com/4yV4JY6

As part of the two-day celebration for our Passion in Science Awards, award winners were guided through bacterial agar art creation! NEB Principal Scientist Mehmet Berkmen is always excited to share his love for microbes of all colors and shapes 🧫

Our final awardee presenter is Rojelio Mejia, M.D., who won a Passion in Science Humanitarian Duty Award for the My Poverty and Parasite Nexus project, which he founded to connect parasites, poverty and more through science and advocacy.

Can you imagine what it would be like to learn about chemical concepts through textile art practices? Passion in Science Arts and Creativity Award winner Anne-Frances Miller has developed courses that use natural dye to support hands-on projects!

Presenting for the Passion in Science Awards, Scientific Mentorship and Advocacy Awardee Richard O'Rorke highlights The DNA Drive project and the impact of citizen science 🔬

Our first Passion in Science Awardee presentation of the day! Environmental Stewardship Award Winner Chukwudi Ikegwu spotlights his conservation work in Nigeria using eDNA and bioacoustics for non-invasive amphibian biodiversity monitoring 🐸

RNA-seq speed without compromise! Learn how NEBNext UltraExpress RNA can be applied to samples down to 1ng in our new technical note, "Application of NEBNext UltraExpress RNA to low-input RNA samples" https://nebiolabs.com/4xZp3pQ

New Student Starter Pack requests are now open! First-year graduate students and first-year post-docs can get the jumpstart they need for the lab with our starter pack, containing technical references, lab supplies, and NEB swag. Learn more and see T&Cs: https://nebiolabs.com/46Qrlg2

Today's the day! Stock up on your lab reagents and support the Monarch butterflies with US catalog sales for our Monarch Day. Learn more at www.neb.com 🦋

Earlier this month, NEB hosted the 2026 Boston Phage Symposium on our Ipswich campus! We are thrilled to have supported a shared interest in phage research and great talks from four labs from MIT and @harvard.edu !

END nucleases, defense systems within diverse bacteria that target bacteriophages with hypermodified DNA, are identified in a Nature Microbiology study by NEB researchers and collaborators. https://www.nature.com/articles/s41564-026-02407-2

In our latest podcast (https://nebiolabs.com/4yJC1c3), microbiologist and virologist Dr. Paul Turner, from Yale School of Medicine, joins us to explain how bacteriophage can be used to treat and kill bacterial infections, and what the future of this technology looks like.

Our Passion in Science Award winners from around the world have been notified! We're excited to share the full list of awardees: https://nebiolabs.com/4xYpdP5

Less than two weeks left until NEB's Monarch Day! Learn more about Monarch Day and how US catalog sales can help support Monarch butterflies at www.neb.com

In our latest blog, see how RNase 4 can be used to digest long mRNA molecules into oligonucleotide fragments amenable to analysis by LC-MS, capillary electrophoresis, or denaturing gel-based methods - enabling detailed assessment of mRNA therapeutic safety & content. https://nebiolabs.com/3T7Y2lS

Considering lyophilized reagents? See an example in Microbiology Spectrum of how they can be used in a rapid & low-cost proof-of-concept workflow for HIV-1 subtype B & HCV genotype 1a molecular detection from blood samples by Public Health Agency of Canada researchers: https://nebiolabs.com/4y1VtB4

In a Microbial Genomics paper (https://nebiolabs.com/4AaYZdJ), University of Copenhagen, NEB, and University College Cork scientists describe the quite large variation in genome composition for Pseudolactococcus laudensis strains from different habitats.

Happy Labor Day! In honor of the holiday and in celebration of the many achievements American workers have contributed to the US, NEB is closed today, Sept. 7.

NEB scientists showcase M. paludis Argonaute (Mpa Ago) as a programmable RNA "restriction enzyme" that can cleave mRNAs at precise, user-defined sites without the sequence constraints of CRISPR-Cas. https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(26)00154-X

The biochemical origin and precise chemical structure of 5-arabinosylcytosine, a cytosine DNA hypermodification, is revealed in a @narjournal.bsky.social publication by NEB, National Research Council Canada, and Brock University scientists: https://pubmed.ncbi.nlm.nih.gov/42391045/

Learn about exciting R&D trends in peptide therapeutics, including what makes custom mRNA display libraries so powerful, in this Q&A with the founders of PeptiFinder Biotech: https://nebiolabs.com/4gy4Y3t

In a collaboration between Fred Hutchinson Cancer Center, Seattle University, NEB and other labs, a Nucleic Acids Research paper shows a subcomplex of three BREX proteins, demonstrating that BrxC is a DNA-binding ATPase that can switch between multimer forms. https://nebiolabs.com/4girjBL

Bioinformatic searches identified a new toxin-antitoxin system in M. tuberculosis that researchers from Universite de Toulouse, Durham University, NIH, and NEB have named RelSI. When released, the toxin cleaves the 16S rRNA and removes the anti-Shine-Dalgarno region. https://nebiolabs.com/45DVkHu

Our Molecular Biology Summer Workshop, hosted at Quinnipiac University, took place at the end of July! Read more about the workshop and view photo highlights from the 2-week intensive in Quinnipiac Today: https://nebiolabs.com/4qnPjIx

SRM University-AP, CSIR-IICB, Jadavpur University, University of South Florida, and NEB researchers present an end-to-end framework to ID cell-specific protein markers commonly regulated across mild-moderate AD, early-stage PD & MS in peripheral blood mononuclear cells. https://nebiolabs.com/4qq8y47

In an ACS Synthetic Biology paper, NEB scientists present a microfluidic workflow that couples reconstituted in vitro transcription–translation with ultrahigh-throughput droplet screening to directly link genotype and phenotype within complex, heterogeneous DNA pools: https://nebiolabs.com/4fSeqj2

NEBNext EM-seq v2 has a shorter, more streamlined workflow for ≤100 ng, making it the fastest (<4.5 hrs), broadest input range, and most reliable enzymatic methylation solution available. https://nebiolabs.com/4wXbBmO

Our webinar on mRNA characterization is tomorrow! Don't forget to learn more and register at https://nebiolabs.com/4fK9pZH

Don't miss your chance to submit a nature-themed photo for our 2027 calendar! 🐞 If selected, you'll receive $500 in NEB product credit or $500 to donate to a charity of your choice! Learn more about terms & conditions and submit your photography by Sept. 15 at https://nebiolabs.com/3TKtd6C

Our next webinar on August 12 at 1 pm EDT will showcase two complementary approaches for mRNA characterization! Learn more and register at https://nebiolabs.com/4fK9pZH

The @genesinspace.bsky.social competition winners have been selected! Congratulations to Bronx High School of Science juniors Serena Tsao & Chloe Comisarow. We're excited to work with them and the Genes in Space team to finalize their experiment for launch to the ISS! https://nebiolabs.com/4fOTbNE

CariGenetics founder Dr. Carika Weldon joins the NEB podcast (https://nebiolabs.com/4wwTUtT) to share her experience as part of the COVID pandemic response in Bermuda and how that led her to focus on bringing genetic research expertise and equipment to the Caribbean.

New product release! The Monarch® Mag Cell-free RNA (cfRNA) Extraction Kit (https://nebiolabs.com/4xjaDkF) provides efficient, reproducible extraction of total circulating cell-free RNA and exosomal-associated RNA, without needing organic extraction chemistry or cumbersome vacuum manifolds 🦋

Today is your last chance to meet the NEB team bringing custom enzyme solutions! Our team is ready to talk all things enzymes and reagents at Booth 4111 at #ADLM2026

From custom enzyme solutions to innovative products like Q5®‑XT and Bst‑XT WarmStart™, NEB is ready to support your assay development. Visit us at #ADLM2026 (Booth 4111) to start a conversation about how we can help your research!

At #ADLM2026? Visit NEB at Booth 4111 to learn more about our Monarch Cell-free DNA and cell-free RNA Extraction solutions 🦋

NEB offers automation-friendly and lyo-compatible enzymes and solutions such as Murine RNase Inhibitor (Glycerol-free) (https://nebiolabs.com/4bIiWOs). Drop by the NEB booth (4111) at #ADLM2026 to talk with the team!

Searching for the latest enzymes for molecular assay development? Stop by NEB’s booth (4111) to learn about our newest developments! #ADLM2026

Looking for a partner with 50+ years of experience working with global assay developers on innovative enzyme solutions? Connect with the NEB team at #ADLM2026 (Booth 4111) to talk about your enzyme and reagent needs. https://nebiolabs.com/4wjeHkG

NEB is attending #ADLM2026 in Anaheim! Stop by booth 4111 to meet the team and learn about how we are supporting MDx assay development around the globe 🌎

Thank you for sharing your passion in science with us! We're in the final stages of reviewing the inspiring applications for our 2026 Passion in Science Awards, and winners will be notified within the next two weeks 🦋

High-quality, pure RNA is a requirement for RNA therapeutics to avoid unwanted immune responses, not just a “nice to have.” The enzymatic removal of dsRNA using RNase III preserves ssRNA integrity when refined using a protocol for IVT samples. https://nebiolabs.com/4b4AofP

Cell-free protein synthesis (#CFPS) workflows allow for fast, scalable & cost-effective single-chain Ab fragment production. In this blog post, read about how you can quickly & efficiently screen the discovery and initial characterization of novel antibody fragments: https://nebiolabs.com/3SWKI3q

Today is the birthday of Don Comb, the founder of New England Biolabs. Don was dedicated to environmental stewardship, philanthropy, and scientific innovation. NEB remains guided by these values, and we thank Don for his commitment and passion to science. In Don's honor, we will be closed today.

Happy Independence Day! NEB will be closed today in honor of 250 years of independence.