Patrick Kidger

You: please act normal, you need these people to like you Me: ok! People: hi Me: there is a parasite on salmon called Henneguya zschokkei which started as a jellyfish cancer before *budding off into its own species*.

Alright chaps, I am in Boston for PEGS, here to chat all things AI + antibody engineering. Send me a message if you're around! 🧬 (PS I'm hiring! Pharma x AI startup, come make drugs with us.)

🚀 New talk! "Automated ML-guided lead optimization: surpassing human-level performance at protein engineering" ▶️ www.youtube.com/watch?v=mEhB... ✨🧪 This was a talk I gave at the recent AIxBIO conference in Cambridge UK. A 10-minute pitch for what we do at Cradle!

A reminder that there is now *1 week* left until the MLSB deadline on October 1st! Send in your 🧪bio+🤖ML papers, for either 🇺🇸San Diego, 🇩🇰Copenhagen, or ✨both✨!

💥 We are *also* organizing Machine Learning for Structural Biology @ EurIPS, Copenhagen!! Topics include anything in the ML+bio intersection. Submit your ML+bio short papers! Authors can even present in both locations if they have people in both locations 🚀

🚀 So `tinyio` hit the front page of Hacker News. Now we're at 487 GitHub stars :D I've also just done a ✨v0.2 release✨. Now comes batteries-included with common operations (locks, yield-as-available, etc.) and with a major performance improvement. GitHub: github.com/patrick-kidg...

✨v0.1 release of typst_pyimage!✨ Do you: - write scientific papers in Typst (boo hiss LaTeX)? - have many matplotlib figures? Would you like the code for those images inlined directly into your Typst file, and autogenerated when you compile it?🔥 github.com/patrick-kidg...

✨Announcing: tinyio! A tiny barebones event loop library for Python. Born out of my frustration with asyncio... GitHub: github.com/patrick-kidg... It's nothing too fancy, just a little library that does one thing well. 🔥

✨ We are hiring to build out our automated wet lab! 🤖🦾🧪 jobs.ashbyhq.com/cradlebio/27...

At CERN the next couple of days for a workshop. Send me a DM if you're around too 🚀

Oh this is pretty cool 😃 ESM-C protein language model in JAX+Equinox!

🌟 We have a proteinML PhD internship at Cradle! jobs.ashbyhq.com/cradlebio/d8... Come see what it's like to work at a frontier bioML lab. This is a unique opportunity to work across the entire stack: 🔬 Automated wet lab data; 🤖 Train your own ~1B parameter ML models; 📚 Publish end result! 🚀

🌟 We have a proteinML PhD internship at Cradle! jobs.ashbyhq.com/cradlebio/d8... Come see what it's like to work at a frontier bioML lab. This is a unique opportunity to work across the entire stack: 🔬 Automated wet lab data; 🤖 Train your own ~1B parameter ML models; 📚 Publish end result! 🚀

✨ I wrote a new blog post! 🤖 RealSemVer: or, how Semantic Versioning _really_ gets used. kidger.site/thoughts/rea...

In school, you probably learned that human cells have 46 chromosomes, which is 2 copies of 23 chromosomes, sometimes called 'diploid' or '2n'. But there are other 'ploidies' in your cells. To start with, 80+% of your cells have NO chromosomes: red blood cells or 'erythrocytes'...

FutureHouse is launching an independent postdoctoral fellowship program for exceptional researchers who want to apply our automated science tools to specific problems in biology and biochemistry, in collaboration with world-leading academic labs. 1/

🔥 How we won the Adaptyv Bio competition, designing a 1.21nM binder to EGFR using generative AI :) www.cradle.bio/blog/adaptyv... 🌟 This was a super fun project from four of us at Cradle Bio ! ✨

🎉 Okay folks it's that time of year! Who's at NeurIPS?? Come find me and the rest of the Cradle Bio crew 🧪 Always happy to chat sciML, protein design, open source, and everything in between 🌟

✨ wheeeeee we raised a series B AI-powered automated protein optimization: matches or exceeds human performance, works without human intervention. It's pretty cool :D (PS if you're seriously good at ML eng then we're hiring) www.cradle.bio/blog/series-b

*Building neural networks in Equinox* Third lab for the course, after JAX and Keras we see Equinox (from @patrickkidger.bsky.social) - including callable pytrees, stateful modules, and filtering. Stay tuned for part b with a text classification model. 😎 colab.research.google.com/drive/19NHkb...

Good software is an enabler for good science! 💥🧪 Inspired by the below post, I like to point people at libraries like github.com/patrick-kidg... as a template for what a modern Python library looks like: `pre-commit`, ruff, pyright, pyproject.toml, an open-source license, etc. 🤓

Now this is awesome! I love the way that ML, with its open-source-everything approach, is taking on biology.

We have an AI-designed antibodies challenge! 🔥 Nature: www.nature.com/articles/s41... Website: www.aintibody.org (Co-authored with approximately everyone, haha. 🌟) The challenge is primarily around CDR design, with the submitted sequences tested in vitro. 🧪 Come give it a go :)

Testing testing, 123. Let's find out whether this latest Twitter clone goes anywhere... :D