"Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C" out now in PLOS Biology journals.plos.org/plosbiology/...
De Camilli Lab
De Camilli Lab
@pdc-lab.bsky.social
Laboratory of Pietro De Camilli - Department of Neuroscience at Yale University
256 followers3 following2 posts
journals.plos.orgImpaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13CVPS13A and VPS13C are bridge-like lipid transport proteins with distinct subcellular localization and function, and their absence is linked with chorea-acanthocytosis and Parkinson's disease, respecti...
"The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage" out now in Nature Cell Biology rdcu.be/ehbaL
rdcu.beThe bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damageNature Cell Biology - Wang et al. show the recruitment of the lipid channel protein VPS13C and formation of VPS13C-dependent contacts between endoplasmic reticulum and lysosomes after lysosomal...
De Camilli Lab reposted
New research from @pdc-lab.bsky.social & collaborators finds that the bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage; #Parkinsons-associated LRRK2 is also recruited but at later stage www.nature.com/articles/s41...
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