Eva Petermann

Eva Petermann

@petermannlab.bsky.social

Investigating replication stress at the University of Birmingham, UK. https://www.evapetermann.org/

342 followers101 following12 posts

Eva Petermann
@petermannlab.bsky.social

OMG fibres can now move!! Frankenstein's fibres!!! 😱 (Spoiler: microtubules)

Journal of Cell Science@jcellsci.bsky.social

Cordula Reuther, Paula Santos-Otte, Stefan Diez and colleagues find that microtubule lattice defects facilitate spastin-mediated severing. journals.biologists.com/jcs/article/... #OpenAccess #ReadandPublish

Eva Petermann
@petermannlab.bsky.social

Our review article on recent RNase H2 in replciation stress and cancer has been published in @jcellsci.bsky.social! Thank you for the invitation Journal of Cell Science @jcellsci.bsky.social and Company of Biologists @biologists.bsky.social. journals.biologists.com/jcs/article/...

journals.biologists.comEmerging roles of RNA:DNA hybrid regulation by mammalian ribonuclease H2 in replication stress and cancerSummary: Control of RNA:DNA hybrids by RNase H2 helps protect genome stability. Recent insights into RNase H2 molecular functions and alterations in cancer shed new light on mechanisms of human diseas...
Eva Petermann
@petermannlab.bsky.social

A follow-up PhD project is now available: www.findaphd.com/phds/project...

findaphd.comRegulation of Ribonuclease H2 for control of R-loops and genome stability at University of Birmingham on FindAPhD.comPhD Project - Regulation of Ribonuclease H2 for control of R-loops and genome stability at University of Birmingham, listed on FindAPhD.com
Eva Petermann@petermannlab.bsky.social

We're very proud that our recent PhD graduate (and now postdoc) Rosie Wilkins' study on RNase H2 overexpression in human cells has been published in Oncogene. www.nature.com/articles/s41...

nature.comHuman RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress - OncogeneOncogene - Human RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress

Eva Petermann reposted

Sarah Lambert's Lab
@lambertsarahlab.bsky.social

A three-year PhD position is available within the team, starting no later than October 2026, to decipher the molecular signatures of chromosomal instability in response to replication stress and how nuclear architecture shapes these signatures in yeast. Please RT. fr.scribd.com/document/934...

fr.scribd.comOffer PhD Position Team Lambert | PDF | Genetics | Life Sciences3-year PhD offer in biology to mechanisms of complex rearrangements of the genome.
Eva Petermann
@petermannlab.bsky.social

A follow-up PhD project will soon be advertised!

Eva Petermann@petermannlab.bsky.social

We're very proud that our recent PhD graduate (and now postdoc) Rosie Wilkins' study on RNase H2 overexpression in human cells has been published in Oncogene. www.nature.com/articles/s41...

nature.comHuman RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress - OncogeneOncogene - Human RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress

Eva Petermann reposted

Ferenc Mueller
@ferencmueller.bsky.social

The Birmingham Centre for Genome Biology invites you to join us at our 10th year anniversary conference! Website and Registration here: shorturl.at/rvJSr Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!

Eva Petermann
@petermannlab.bsky.social

HPV-driven cancers as a model to improve therapy

Nature Reviews Cancer@natrevcancer.nature.com

🚨 PERSEPCTIVE 🚨 TGFβ has a well-established role in cancer, yet its blockade has 🔁ly failed in trials. Barcellos-Hoff & Yom use HPV-driven cancers as a model to explain these discrepancies & emphasize the need for refined strategies to enhance therapeutic efficacy.

bit.lyRevisiting the TGFβ paradox: insights from HPV-driven cancer and the DNA damage response - Nature Reviews CancerTransforming growth factor-β (TGFβ) has a well-established role in malignancy and its inhibition has demonstrated strong preclinical activity. However, TGFβ blockade has repeatedly failed in clinical trials. Here, Barcellos-Hoff and Yom utilize human papillomavirus (HPV)-driven cancer as a model to explain these discrepancies and emphasize the need for refined strategies and understanding of TGFβ signalling to enhance therapeutic efficacy.

Eva Petermann reposted

Ronan Broderick
@brodericklab.bsky.social

Still a few days left to apply! I'm recruiting for two Postdoc positions in my lab at the University of Birmingham, investigating the Alternative Lengthening of Telomeres.

Ronan Broderick@brodericklab.bsky.social

My lab is #hiring! I am recruiting for two #Postdoc positions investigating the Alternative Lengthening of Telomeres mechanism. www.jobs.ac.uk/job/DLO693/r... www.jobs.ac.uk/job/DLP016/r... #Telomere #DNAreplication #DNArepair #cancer #glioma #UKRI #MRC #universityofbirmingham #NGS

jobs.ac.ukResearch Fellow at University of BirminghamDiscover an exciting academic career path as a Research Fellow at jobs.ac.uk. Don't miss out on this job opportunity - apply today!

Eva Petermann reposted

Eva Petermann
@petermannlab.bsky.social

We have a funded PhD studentship available: Join a dynamic research group to study the regulation of RNA:DNA hybrid metabolism for genome stability! www.jobs.ac.uk/job/DKQ744/p...

jobs.ac.ukPhD Studentship: Regulation of RNA:DNA Hybrid Metabolism for Genome Stability at University of BirminghamFind a PhD Studentship: Regulation of RNA:DNA Hybrid Metabolism for Genome Stability on jobs.ac.uk, the top job board in higher education. Click to view more!
Eva Petermann
@petermannlab.bsky.social

We have a funded PhD studentship available: Join a dynamic research group to study the regulation of RNA:DNA hybrid metabolism for genome stability! www.jobs.ac.uk/job/DKQ744/p...

jobs.ac.ukPhD Studentship: Regulation of RNA:DNA Hybrid Metabolism for Genome Stability at University of BirminghamFind a PhD Studentship: Regulation of RNA:DNA Hybrid Metabolism for Genome Stability on jobs.ac.uk, the top job board in higher education. Click to view more!

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