PfefferCryoLab

PfefferCryoLab

@pfeffercryolab.bsky.social

Cryo-electron microscopy, structural biology of molecular machines, ribosome-associated processes, gamma-tubulin complexes

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PfefferCryoLab
@pfeffercryolab.bsky.social

Nearly two decades after augmin's discovery in Drosophila, we have reconstituted the microtubule-binding region of the Drosophila augmin complex on microtubules and demonstrate the conserved mechanism by which augmin subunit HAUS6 orients augmin for microtubule branching.

PfefferCryoLab reposted

Sergey Melnikov
@sergeymelnikov.bsky.social

Here we unexpectedly find that the ribosomal protein S20/L26—identified at the dawn of ribosome research but later deemed a biochemical artifact—is indeed a genuine component of the large ribosomal subunit. More on this ribosome content variation is here: www.nature.com/articles/s41...

nature.comStructurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells - Nature CommunicationsCells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...

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