Floris de Lange

Floris de Lange

@predictivebrain.bsky.social

Cognitive neuroscientist interested in predictive perception and cognition. Head of www.predictivebrainlab.com

3.4K followers654 following21 posts

Floris de Lange reposted

Great thread by @meganakpeters.bsky.social on the AI letter by mathematicians that is relevant for neuro too. AI is clearly useful, but our culture of intellectual debate & training risks being steamrolled by companies whose goals are misaligned with ours. Science has to stay a public good

megan peters 🧠@meganakpeters.bsky.social

I am not a mathematician, so I am not sure if I can formally sign this, but I wholeheartedly concur and would argue that the same is true for all of science. Yes, we want scientific discovery. But -- like flipping to the back of the textbook to look at the answer key --

Floris de Lange reposted

Floris de Lange reposted

Having fun this summer, replicating our reversed latent inhibition effect: Reported a couple of years ago, here we show, contrary to 60 years of research, that people can learn more succesfully about a familiair than a novel stimulus. share.google/YIEYQj9yIPNj...

share.googleNovelty mismatch as a determinant of latent inhibition - PubMedLatent inhibition refers to the observation, made in both human and nonhuman animals, that learning about the relationship between a stimulus and an outcome progresses more rapidly when the stimulus i...

Floris de Lange reposted

Floris de Lange reposted

Paula Rubio-Fernández has been awarded an ERC Advanced Grant for the project COMMON_GROUND. The grant will allow Paula to test and develop a new theory of how people build and manage the shared understanding that makes communication possible. www.mpi.nl/news/paula-r...

mpi.nlPaula Rubio-Fernández receives ERC Advanced Grant for research on common ground in multimodal communication | Max Planck Institute

Floris de Lange reposted

Floris de Lange reposted

1/11 Happy to share our TICS paper on using the flexibility of one of the most basic cognitive functions, perception, to understand one of the most complex cognitive dysfunctions, psychiatric conditions (also my first formal work in computational psychiatry 🎉) 📄: www.cell.com/trends/cogni... 🧵 : 👇

cell.comPerceptual multistability: a multifaceted window into brain dysfunctionsPerceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics a...

Floris de Lange reposted

New PhD studentship available! Come join the excellent @neuromurphy.bsky.social lab for a very cool project exploring how the brain learns to make decisions that are not tied to specific sensory modalities or movements. In collaboration with @seanfw.bsky.social and myself! bsky.app/profile/neur...

Neuroscience Ireland@neuroscienceirl.bsky.social

✅Funded PhD studentship in computational modelling of supra-modal evidence accumulation/decision-making! ⏰ Closing date: 1st July 2026! ➡️ More information: shorturl.at/FsTQ0 @redmondoconnell.bsky.social @seanfw.bsky.social @maynoothuniversity.ie @tcdpsychology.bsky.social

Floris de Lange reposted

This is one of the most exciting pieces of science I have had the privilege to be involved in, led by @rui-xu.bsky.social‬, Bob Desimone, and Mark Richardson: the discovery of actual long-range monosynaptic connections in the human brain! For example the FFA connects to the rTPJ, how cool is that?

Rui Xu@rui-xu.bsky.social

New preprint as my first post! "Monosynaptic connections link functionally similar regions in human cortex." We use electrical stimulation + fMRI in epilepsy patients to map whole-brain monosynaptic connectivity at 42 cortical sites. doi.org/10.64898/202... 1/n

Floris de Lange reposted

Floris de Lange reposted

“Researchers looked at two high-profile AI agent tools developed to help computer scientists in the field of machine learning. Both systems engaged in acts that violate research integrity, including making up data & p-hacking: running an experiment multiple times but only reporting best outcome.” 🧪

science.orgAI agents may be skilled researchers—but not always honest onesTwo high-profile tools have been shown to make up data and “p-hack” their results

Floris de Lange reposted

Tony is 100% right. This can't be said often enough.

The Transmitter @thetransmitter.bsky.social

Prediction without understanding sustained astronomy through a thousand years of epicycles, writes @tonyzador.bsky.social. AI is now offering neuroscience the same deal. #neuroskyence www.thetransmitter.org/machine-lear...

Floris de Lange reposted

Floris de Lange reposted

New paper alert: very proud to share our review published in Trends in Cognitive Sciences, spearheaded by @maellelerebourg.bsky.social, and together with @peelen.bsky.social and @predictivebrain.bsky.social, about goal-directed search in real-world environments. See below for a thread/tldr!

Maëlle Lerebourg@maellelerebourg.bsky.social

What do we look for when searching for objects in our daily-life environments? Very happy that I can now share this review, together with @suryagayet.bsky.social , @predictivebrain.bsky.social and @peelen.bsky.social🥳 A brief thread below!

Floris de Lange reposted

What does it mean for cognition to be Bayesian? The view that cognition is Bayesian inference is often intended at Marr's computational level. In a new paper in Nat Rev Psych, @kaixue98.bsky.social and I formulate the "explicit-Bayes" hypothesis that lives at the algorithmic level. rdcu.be/ff1XA

rdcu.beThe explicit-Bayes hypothesis for cognitionNature Reviews Psychology - It is often asserted that human cognition is Bayesian, but that broad claim is difficult to test in a falsifiable way. We suggest that researchers specifically assess a...

And a nice summary by Richard Antonello can be found here: elifesciences.org/articles/111...

elifesciences.orgLanguage Models: Does the brain really know what word is coming next?Apparent neural encoding of future words may arise from the statistical structure of language itself, rather than from predictive computations in the brain.
ines-schoenmann.bsky.social@ines-schoenmann.bsky.social

New peer-reviewed paper w/ @mheilbron.bsky.social, @predictivebrain.bsky.social & Jakub Szewczyk! Pre-onset brain encoding has been taken as evidence that brains–like LLMs–predict upcoming words. We show that the same signatures arise in systems that cannot predict. (elifesciences.org) (1/8)

Floris de Lange reposted

I think this chart is absolutely wonderful for people who think about the environment but find it hard to cut on meat. Remember: eating a bit less beef is much easier than going full veg(etari)an, while still helping a lot. And after a while you notice that you don't even need it that much... 🤷‍♀️

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Floris de Lange reposted

Floris de Lange reposted

Our work on how neural circuits in the cerebellum encode prior probabilities led by Julius Koppen is out now in Nature Neuroscience www.nature.com/articles/s41... Big thanks to Julius Koppen & the whole team! And dedicated to all of us who found inspiration in Bayesian theories of the brain!

nature.comNeural circuits encode prior knowledge of temporal statistics - Nature NeuroscienceThis study shows that cerebellar circuits learn and encode prior probabilities of event timing. Cell-type-specific neural activity reflects environmental statistics and guides predictive motor behavio...

Floris de Lange reposted

Very interesting sounding paper on the role of the default mode network in visual perception by Ujhelyi, Korda & Zaretskaya. The authors propose that the DMN provides top-down information from memory and semantic knowledge to guide perception. #neuroskyence

cell.comThe contribution of default mode network areas to visual perceptionVisual perception and accompanying sensory activity are strongly shaped by top-down influences. Although several sources of this influence have been thoroughly examined in the research literature, one...

Floris de Lange reposted

@lisafeldmanbarrett.com @earlkmiller.bsky.social #neuroscience #neuroskyence The Perspective article by Lisa Feldman Barrett and Earl K. Miller states that categorization is a fundamental property of the brain and.....

Nature Reviews Neuroscience@natrevneuro.nature.com

Categorization is ‘baked’ into the brain — a Perspective by Lisa Feldman Barrett & Earl K. Miller @lisafeldmanbarrett.com @earlkmiller.bsky.social #neuroscience #neuroskyence www.nature.com/articles/s41...

Floris de Lange reposted

Floris de Lange reposted

fully agree with Stefano. I spent years of my training learning to translate scientific thinking into models and code. if that’s no longer a bottleneck, what was the point — and what should replace it?

Stefano Palminteri@stepalminteri.bsky.social

🧵 I gave Claude two things: a short paper (doi.org/10.1073/pnas...) and a raw behavioural dataset with 3 lines of variable descriptions. Then I asked it to fit three computational RL models described only by equations in the manuscript. No code, no toolbox, no guidance on the fitting procedure. 1/3

Floris de Lange reposted

New preprint! w/ @mheilbron.bsky.social We found that, even during simple natural scene viewing, human visual cortex predicts—hierarchically in central vision and at higher levels peripherally—reconciling classical predictive coding with recent evidence from animal models and AI (e.g. JEPA) (1/10)

Floris de Lange reposted

What are the systems in neuroscience that we really have something that we can call “explanation” at all relevant levels, other than reflexive feed-forward like circuits. Here are a few that I would argue are getting there. Obviously not complete explanations but genuinely satisfying.

The Transmitter @thetransmitter.bsky.social

Neuroscience has become increasingly concerned with prediction, and machine learning with causal explanation, with each field adopting methods from the other, writes @gershbrain.bsky.social. Will this bring us closer to understanding neural systems? www.thetransmitter.org/the-big-pict...

Floris de Lange reposted

Floris de Lange reposted

Very happy that this paper from our lab is now out in @pnas.org! What happens when the *same* person experiences the *same* information with a *different* interpretation? Nearly the whole 🧠—well, at least nearly all association cortex—changes how it represents that information! tinyurl.com/p8chj2j7

tinyurl.comPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Floris de Lange reposted

Floris de Lange reposted

Floris de Lange reposted

DNN models of the brain are getting bigger. Are we replacing one complicated system in vivo with another in silico? In new work, we seek the *smallest* DNN models of visual cortex, balancing prediction with parsimony. It turns out these compact models are surprisingly small! rdcu.be/e5H8G

rdcu.beCompact deep neural network models of the visual cortexNature - Parsimonious deep neural network models can be used for prediction of visual neuron responses.

Floris de Lange reposted

Floris de Lange reposted

Floris de Lange reposted

Great opportunity to work in a terrific lab:

micha heilbron@mheilbron.bsky.social

📢 PhD position in the NeuroAI of Language Why can LLMs predict brain activity so well? We're hiring a PhD student to find out -- AI interpretability meets neuroimaging Deadline March 20 Please RT 🙏 👇 mpi.nl/career-education/vacancies/vacancy/fully-funded-4-year-phd-position-neuroai-language