Juanma Schvartzman

Juanma Schvartzman

@schvartzman.bsky.social

metabolism + chromatin biologist #chroMetab lab, GI medonc @columbiacancer and dad | 🇪🇸🇵🇾🇦🇷🇺🇸 | @Schvartzman_JM | @schvartzman.bsky.com

2.4K followers1.6K following19 posts

Juanma Schvartzman reposted

Maya Emmons-Bell
@maya-emmonsbell.bsky.social

@schvartzman.bsky.social and I wrote a perspective on how dynamic metabolite-protein interactions can shape cell biology, and the open questions this raises about the broad roles of metabolism. It was fun to dig into Zabala-Letona, Carracedo et al.'s story as an example of this! tinyurl.com/4tcnrydm

tinyurl.comPrecision from broad strokes: How the non-specific interactions of metabolites and macromolecules can regulate biologyIn a recent article in Nature, Zabala-Letona et al.1 propose that polyamines—small, positively charged metabolites—regulate RNA splicing by electrosta…

Juanma Schvartzman reposted

Save Our Cures
@saveourcures.bsky.social

Today's research assistants, tomorrow's cure-finders: Federal funding helps train the next generation of biomedical scientists. By investing in researchers today means investing in decades of future discoveries. Speak up: http://fundresearch.org #SaveOurCures #ScienceEducation #FutureReady

Juanma Schvartzman reposted

Lucas Sullivan
@lucasbsullivan.bsky.social

Our work detailing the metabolic roles of serum for cancer cell proliferation is now out at JBC, @asbmbjournals.bsky.social! Congrats to Oliver and Eric and many thanks to the editor and reviewers for a thoughtful and efficient review process. See here: www.sciencedirect.com/science/arti...

sciencedirect.comDefined media reveal the essential role of lipid scavenging in supporting cancer cell proliferationFetal bovine serum (FBS) is an undefined additive that is ubiquitous to mammalian cell culture media and whose functional contributions to promoting c…
Lucas Sullivan@lucasbsullivan.bsky.social

Excited to share a recent preprint by Oliver Newsom, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside: A broadly applicable serum-free media, Quantitative lipid uptake characterization, Evidence lipid scavenging > synthesis for cancer cell proliferation.

Juanma Schvartzman
@schvartzman.bsky.social

There are so many stories like this. A weird colony in a plate in the rubbish to penicillin, fly eyes to ras inhibitors, weird repetitive sequences in bacteria to CRISPR. We should have a daily column on how science made your life better. #fundscience

Marcelo Bonini, Ph.D.@mbonini.bsky.social

The story of ozempic - besides saving millions of lives and saving billions for the healthcare system - ozempic is a scientific breakthrough everybody should know about - it was discovered because someone studied the spit of a lizard that only eats 6 times a year the Gila monster - so first 🧵

Juanma Schvartzman reposted

Jeremy Berg
@jeremymberg.bsky.social

Bluetorial: Women, courage, and leadership What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.

Juanma Schvartzman reposted

Cynthia Wolberger
@cwolberger.bsky.social

I was that woman! I have frequently told the story of how Jeremy responded after my second NIH rejection. He said, “Whatever you do, don’t stop spending. If you run out of startup, we’ll find more money for you.” I didn’t need it in the end, but knowing he had my back was huge. Thank you!

Jeremy Berg@jeremymberg.bsky.social

Our first recruit struggled initially to succeed in obtaining NIH funding. But her science was/is terrific and we bridged her along. She subsequent received an HHMI appointment, and then substantial NIH funding. She is now a member of the National Academy and is the current department director 25/n

Juanma Schvartzman
@schvartzman.bsky.social

A patient reminded me of science’s power: 2 doses of immunotherapy and a fatal cancer GONE. Immunotherapy exists BECAUSE of basic research—work that can seem esoteric or wasteful. Before dismissing it, ask a scientist why it matters. Or ask the Nobel who discovered immunotherapy.

Juanma Schvartzman
@schvartzman.bsky.social

rupress.org/jcb/article/... A great piece on the life of Joe Gall, a giant of modern cell and molecular biology. Especially 👍 to the importance of exploring nature, model systems and supporting women in science. Really inspiring

rupress.orgJoseph G. Gall (1928–2024): Cell biologist, naturalist, and mentor extraordinaire | Journal of Cell Biology | Rockefeller University PressJoseph Grafton Gall (1928–2024), a founder of modern cell biology, made foundational discoveries on eukaryotic chromosomes and RNA biogenesis.

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