Our bones may seem like static structures, but they’re constantly being broken down & rebuilt. Boniva works by slowing the cells responsible for bone loss, reducing fracture risk over time. My latest video explains the biology behind this process! youtu.be/U_6Zubayb8I
Rob Swanda
Rob Swanda
@scientistswanda.bsky.social
Making Science Accessible & Understandable | (educational purposes only, not medical advice) | https://www.youtube.com/c/RobSwandaPhD
921 followers25 following614 posts
Cancer treatment innovation isn't always about a new drug, sometimes it's about a better way to deliver it. Rybrevant Faspro transforms a lengthy infusion into a short injection, saving valuable time for patients, caregivers, and healthcare teams. Learn about it in my latest! youtu.be/jNVRyJuZm88
Your liver does a lot more than process nutrients. It also acts as a communication hub, responding to growth hormone signals by producing IGF-1, one of the body's most important growth and repair molecules. Learn how this pathway regulates growth & metabolism in my latest video! youtu.be/EdVn5vhGa5o
my prior video explainer breaking down this treatment: youtu.be/lCrR1JcPH-I
Eloralintide is an investigational amylin receptor agonist built for extended metabolic signaling. Its engineered design aims for longer receptor engagement than earlier incretin peptides. Check out my new video on this medication to learn more! youtu.be/6_1GXZdbjO0
NEW cancer treatment in Phase3!! Petosemtamab targets EGFR at a unique epitope to disrupt tumor‑driven signaling. This specific binding is what makes it stand out in early oncology research. Explore its mechanism in my new educational lesson! youtu.be/-Wsn4d0tJQ0
Rybrevant is a bispecific antibody targeting both EGFR and MET to block parallel tumor‑growth pathways. The formulation delivers broad systemic receptor engagement. My new video discusses its implications in the lung oncology space. youtu.be/sC3Rz9nHWxA
Ibutamoren activates the GH receptor to trigger GH and IGF‑1 release without injections. Researchers are exploring its mechanism for certain orphan‑disease pathways tied to endocrine signaling. Learn more about it in my latest video! youtu.be/ZDDFbAzOTs4
Berberine is a plant-derived compound and researchers are uncovering fascinating clues about how it interacts with metabolism. Its proposed mechanisms involve AMPK activation & mitochondrial signaling. Explore these pathways in my latest educational lesson! youtu.be/DG_QQ09HKAA
Evenity is an osteoporosis therapy that targets one of the body’s key regulatory proteins. Its action slows bone breakdown, offering support for people with severe osteoporosis. Discover how this mechanism improves bone density & strength in my latest video. youtu.be/Z69aNmpfqB0
Plague is one of the most fascinating infectious diseases in history, and it actually comes in 3 forms. Understanding how plague is transmitted and the treatment options is important. And yes, it’s even been in the news again recently, so I’m covering the basics in my new video. youtu.be/SGk2HjiGLKM
Eastern equine encephalitis is a rare but severe viral infection that causes rapid inflammation of the brain. Its transmission moves between birds and mosquitoes, with humans and horses as accidental hosts. I cover the basics in my new lesson. youtu.be/6rrqnkyik20
Riximyo is a biosimilar to rituximab that targets CD20 on B cells to drive precise immune depletion. This therapy has become a cornerstone in treating B‑cell lymphomas & autoimmune diseases. Learn how this clearance works in my latest video! youtu.be/zAXZS0rp72c
Melanotan‑2 is a research peptide that activates melanocortin receptors to drive melanin production. Scientists explored it for photoprotection, but its receptor activity also affected appetite. My new video covers how MT‑2 interacts with receptors! youtu.be/pzdbqV3trVw
Dacarbazine is one of those cancer drugs that looks simple but unleashes a powerful DNA‑damaging punch. After liver enzymes activate it, it disrupt DNA replication and pushes tumor cells toward cell death. Explore the full mechanism in my newest video! youtu.be/HZ37yvQO5DM
Oxyclozanide is an antiparasitic that helps protect livestock from harmful internal parasites. Its mechanism disrupts the parasite’s ability to generate energy, weakening it from the inside out. Explore how this targeted approach works in my new lesson. youtu.be/nO50PxPBxns
Sermorelin is a research peptide that helps scientists explore how the body regulates growth hormones. Its mechanism offers a look at upstream signaling rather than directly replacing hormones. Learn more about how this pathway operates in my latest video! youtu.be/w1CLYgmMmyE
Alzheimer’s research has expanded rapidly, with progress now happening across diagnostics, biomarkers, and therapeutics. New tools are helping detect disease earlier, understand it more clearly, and explore multiple treatment pathways. Learn more 👇 youtu.be/MXi-z90dP4Y
Multiple sclerosis involves misdirected immune activity, and Gilenya was one of the first therapies to change how those immune cells move. It works by redirecting lymphocytes rather than eliminating them. Explore the full breakdown in my new video. youtu.be/DPLKBcbdz2k
In my new video, I break down how a mitochondrial-derived peptide responds to cellular stress and helps fine-tune how cells use fuel. If you’ve heard the buzz about MOTS-c in aging, exercise, or metabolic research, this lesson will explain it! youtu.be/G-EGnaa1uTs
DAC chemistry turns a short‑acting biologic into a long‑acting therapeutic. By using a linker to bind albumin, the molecule stays in circulation far longer and releases its payload slowly over time. Learn how this modification is useful for biologics in my new video! youtu.be/xNBKzlIQRLs
Praluent is a great example of how blocking a single protein can reshape cholesterol metabolism. By inhibiting PCSK9, it preserves LDL receptors on the liver and dramatically increases LDL clearance. Learn how this mechanism works in my new science video! youtu.be/L0GS8L3mZWA
TKIs and BTK inhibitors are targeted therapies that shut down key signaling pathways cancer cells rely on for survival. Each class blocks different kinase “switches,” shaping how they’re used across solid tumors & blood cancers. My latest lesson highlights how they work. youtu.be/NJXt-CVtrvA
SS-31 is an interesting mitochondria targeting peptide used in research today. By binding cardiolipin, it stabilizes the inner mitochondrial membrane to boost ATP output. Learn how this tiny peptide rewires mitochondrial efficiency in my new video! youtu.be/E2xhYiWNvk8
Glutathione (GSH) is your body’s master antioxidant, working nonstop to neutralize oxidative stress and keep cells functioning at their best. Learn how this tiny molecule pulls off such a big job in my short explainer video! youtu.be/gtF7UV2Qncs
NAD⁺ and NADH are essential metabolic cofactors that shuttle electrons to power energy production. These molecules support ATP generation, DNA repair, and mitochondrial resilience. My latest lesson explains how this redox pair works! youtu.be/bdnSz5sQDoE
Tesamorelin shows how activating a precise hormone pathway can reduce harmful visceral fat. This therapy targets deep abdominal adiposity linked to lipodystrophy. Check out my short lesson to learn more! youtu.be/DAs3mKbyvJA
Radioligand therapy delivers radiation directly to cancer cells using molecular targeting, creating one of the most precise treatment approaches in oncology. These agents act like homing beacons and my new lesson explores how this strategy improves treatment accuracy! youtu.be/G5DhTP8XTkQ
GHK‑Cu is a naturally occurring copper‑binding peptide widely studied for its regenerative and anti‑inflammatory potential. Researchers are exploring its role in tissue repair and cellular signaling. My new lesson breaks down how this small peptide works! youtu.be/Q19Lkc-GV7o
could you picture a single monthly GLP‑1 injection changing the game? well, Maritide is pushing that future forward! learn more in my short explainer! 😊 youtu.be/MdLhS-MUDQI
Rezdiffra is the first therapy designed to directly reactivate liver metabolism in MASH. By selectively targeting THR‑β, it reduces liver fat and improves fibrosis. I walk through how this liver‑specific mechanism works in my new video! youtu.be/E8DYjDMb4m4
Blinatumomab is one of the most precise immune‑engineering tools in modern oncology. It physically links T-cells to CD19+ leukemia cells to force targeted killing. I break down this mechanism as we enter Childhood Cancer Awareness Month. youtu.be/H3vJlqIGKYU
Ipamorelin is a research GH secretagogue studied in many pathways. It selectively activates the ghrelin receptor to trigger controlled, physiologic growth hormone pulses. Learn how this targeted signaling works in my new video. youtu.be/7iUeiZZTX1I
Metformin is one of the most important tools we have for keeping blood sugar in check & protecting long‑term metabolic health. To learn how it works, check out my short video! youtu.be/QkOsHUbZVF4
It’s that time of year again to breakdown the updated 2026–2027 COVID vaccine, which now targets the XFG variant. Will you be getting yours? youtu.be/O6vo2sKiPUk
Flu season is upon us and the 2026–2027 flu vaccine was fully updated due to shifts in circulating H1N1, H3N2, and B/Victoria strains. I break it all down in my newest educational video! 😊 youtu.be/W_HeCIhJD7U
CJC‑1295 is a long‑acting GHRH analog designed to extend growth‑hormone signaling. Research also shows it sustains pituitary receptor activation rather than just replacing GH directly. I break down the evidence and mechanism in my new educational video! youtu.be/OBs1CBHLgvU
Last year I broke down the promising Phase 2 data behind the mRNA melanoma vaccine. With all the buzz from the latest positive updates on its progress, now’s the perfect time to remind you exactly how this treatment works! 😊 youtu.be/lCrR1JcPH-I
Adtralza (EU designation) is a targeted biologic that calms the immune pathways in eczema. By blocking a key signal behind inflammation & itch, it helps restore healthier skin from the inside out. To learn how it works, watch my latest video! youtu.be/iYaFp6UQKOg
Enhertu is a major step forward in targeted cancer therapy by directly finding HER2+ tumor cells. This molecule increases cancer‑cell killing while limiting exposure to healthy tissues. Learn how it works in my latest video! youtu.be/M7n4ycv9uDo
mRNA clinical trial for lung cancer!! let’s go 🫶 help spread the word, they are recruiting! youtube.com/shorts/Lwh48...
Tecfidera is a MS therapy designed to protect nerve cells from inflammation. It works by reducing oxidative stress damage to neurons, which alleviates symptoms. In my new video, I break down how this mechanism works for patients! youtu.be/EZyDOLL2Dj0
Bispecific antibodies are engineered to latch onto two different molecules at once, helping cancer treatments hit tumors with more accuracy. Want a quick, simple breakdown of how they work? Watch my short video to learn more! youtu.be/takkdJ9wUzY
Bimagrumab is an investigational mAb that promotes muscle growth & prevents muscle loss. By inhibiting myostatin/activin signaling, it lifts the molecular “brakes” that normally limit muscle mass. Watch my new video to learn about the clinical studies. youtu.be/yLhXICUGh_Q
Reclast protects our bones by shutting down overactive bone destroying cells. It binds tightly to bone surfaces and disrupts the mevalonate pathway, which reduces bone breakdown. Check out my new video to see how this once‑yearly infusion strengthens skeletal structure! youtu.be/lbCNN5CX1Kc
Taurine is a unique amino‑sulfonic acid that quietly supports mitochondrial stability. Inside cells, it helps maintain proper mitochondrial protein production. Watch my short video to learn how this small molecule plays a big role! youtu.be/gLpd4JsOOnU