Scripps Research

Scripps Research

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Scripps Research is one of the world's largest, private, non-profit biomedical research organizations. We are Science Changing Life.

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Scripps Research
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A major concern this flu season is reassortment, when seasonal flu and bird flu infect the same host and swap genetic material, potentially creating a new, more dangerous strain. With H5N1 in cows and human cases emerging, our virology labs are closely tracking its evolution. More: ow.ly/thLP50WafhH

Scripps Research
@scripps.edu

The Scripps Research Alumni Network has named Professor Emeritus Richard Ulevitch and Merck Senior Vice President Rob Garbaccio recipients of its inaugural Distinguished Alumni Awards, honoring the exceptional impact of institute alumni on science and society.

ow.lyScripps Research bestows inaugural Distinguished Alumni Awards - Scripps ResearchThe Scripps Research Alumni Network has announced the two divisional winners of its inaugural awards program, created to honor institute alumni for the exceptional impact their professional achievements have had on science and society.The Distinguished Alumni Award in academia has been given to Professor Emeritus Richard Ulevitch, while Rob Garbaccio, senior vice president at Merck, was chosen to receive the Distinguished Alumni Award in industry and entrepreneurship.
Scripps Research
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Scripps Research Nobel laureates Ardem Patapoutian and K. Barry Sharpless are among the first honored by the Wertheim Laureate Prize. Each will direct $250,000 to a qualified charitable organization of their choosing, while sharing knowledge through lectures and visits worldwide.

ow.lyScripps Research Nobel laureates Ardem Patapoutian and K. Barry Sharpless among first honored by new Wertheim Laureate Prize - Scripps ResearchThe newly launched Wertheim Laureate Prize invites Nobel laureates across all six fields from the last five years to direct charitable funds to the causes they believe “will do the most good.” Inspired in part by relationships with Scripps Research scientists, the prize also brings laureates to Wertheim institutions and affiliates around the world to share their knowledge with students, professors and researchers through an international lecture and visitation program.
Scripps Research
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That’s a wrap on our third annual Biotech Innovation Summit! Today, scientists, industry leaders and investors came together at Scripps Research to explore how AI and emerging technologies are helping move discoveries from the lab toward new treatments.

Scripps Research
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Special thanks to our sponsors for making it possible: Collaborative Drug Discovery - CDD Vault, Cooley LLP, Johnson & Johnson, Ligand Pharmaceuticals, Quarles & Brady LLP, Marsh McLennan, Savills, Silicon Valley Bank and Umberg/Zipser LLP.

Scripps Research
@scripps.edu

Two years ago today, we dedicated the Chi-Huey Wong Laboratories for Biomedical Research on our campus. See some before-and-afters of the building’s transformation! 🏗️

Scripps Research
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Scripps Research has named Ron Burkle, founder and managing partner of The Yucaipa Companies, chair of its Board of Directors. A board member since 2017, Burkle brings business and investment experience and a longstanding commitment to philanthropy and nonprofit leadership.

ow.lyScripps Research names Ron Burkle chair of its Board of Directors - Scripps ResearchScripps Research today announced that Ron Burkle, founder and managing partner of The Yucaipa Companies, has been named chair of its Board of Directors. Burkle, who has served on the board since 2017, succeeds John Diekman, PhD, who served two terms as board chair and was recently awarded the Scripps Research Presidential Medal in recognition of his contributions to the institute.
Scripps Research
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Tomorrow, Scripps Research professors John Yates III and Jeffery Kelly, both 2026 Canada Gairdner International Award laureates, take the stage at #GairdnerScienceWeek. The free event, hosted by The Gairdner Foundation, will be livestreamed. Register: https://bit.ly/laureatelectures2026

bit.ly2026 Laureate LecturesThe Laureate Lectures offer a rare opportunity to hear directly from the 2026 Canada Gairdner Award recipients as they share the stories and science behind...
Scripps Research
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Congratulations to Scripps Research science writer Melissa Suran, whose story “Life beyond Crohn’s disease” received an honorable mention in the short-form category of the 2026 National Association of Science Writers (NASW) Excellence in Institutional Writing Awards!

ow.lyAnnouncing the 2026 NASW Excellence in Institutional Writing Award winnersThe National Association of Science Writers and its Awards Committee are pleased to announce the winners of the 2026 NASW Excellence in Institutional Writing Awards.
Scripps Research
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It's #NationalChemistryWeek! 🧪✨ We’re highlighting how the Scripps Research Department of Chemistry seeks to understand matter, create new forms of matter and translate new discoveries into useful products. Learn more about chemistry at Scripps Research at: https://ow.ly/1yTH50ZZ6he

Scripps Research
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Follow along on our Discovery Day scavenger hunt! 🗺️🔬 We stopped at each booth and had so much fun making fascinating discoveries along the way. We can’t wait to do it all again next year! 💙 #ScrippsResearch #DiscoveryDay #scienceexperiments #sciencefair #STEM

Scripps Research
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More smiles from this year's Discovery Day! 🤩 Our graduate students and postdocs had so much fun meeting everyone, answering questions and sharing science through hands-on activities.

Scripps Research
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Next week, the 2026 Scripps Research Biotech Innovation Summit will bring together leaders from science, technology and venture capital to explore how AI is reshaping biomedical discovery. 🗓️ October 22, 2026 | Scripps Research, La Jolla 📲 Request to attend: https://techsummit.scripps.edu/

Scripps Research
@scripps.edu

“Fearless” is the word Laura Nicholson picks to describe the next generation of clinical and translational scientists. A physician and director of education at the Scripps Research Translational Institute, she sees her job as helping her trainees tap into their passion and realize their potential.

ow.lyCommunity Corner: A Q&A with translational science educator Laura Nicholson - Scripps Research Magazine“Fearless” is the word Laura Nicholson picks to describe the next generation of clinical and translational scientists. As a physician and director of education at the Scripps Research Translational Institute, she sees her job as helping her trainees tap into their passion and realize their potential.
Scripps Research
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Christian Diercks invited us into his lab, where he and his colleagues developed T7-ORACLE, a system that continuously mutates selected genes inside E. coli, generating new versions of the proteins they produce. Researchers can then select variants with useful new functions and continue the process.

Scripps Research
@scripps.edu

According to WHO, cancer causes nearly 1 in 5 deaths worldwide. Scripps Research scientists study cancer from individual proteins to whole cells and tissues, uncovering vulnerabilities and advancing promising ideas toward new therapies. More: https://ow.ly/z4kk50ZXiV0 #BreastCancerAwarenessMonth

Scripps Research
@scripps.edu

We’re still buzzing from Discovery Day! 🔬🌟 Visitors built DNA candy models, explored viruses through virtual reality and enjoyed hands-on science with our graduate students and postdocs. Thank you to everyone who joined us and made it possible! More moments to come!

Scripps Research
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Congrats to Assoc. Prof. Keren Lasker on receiving a 2026 DARPA Young Faculty Award to engineer biomolecular condensates as “toxin traps” that capture and neutralize toxins. Once developed, Assoc. Prof. Michael G. Constantinides will lead preclinical studies evaluating their effectiveness.

ow.lyScripps Research associate professor Keren Lasker receives DARPA Young Faculty Award to develop “toxin traps” - Scripps ResearchThe up to $1.14 million award will support engineering of a new method to capture and destroy toxins, which could eventually be used to prevent or limit harm from exposure.

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HHMI
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Proteins can reshape themselves in less than a millisecond. Now, #HHMIInvestigator Dorothee Kern & team @scripps.edu have developed a machine learning model to predict these rapid changes, & it could help researchers uncover new connections between protein movement & human health: bit.ly/4d6klPH

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The Gairdner Foundation
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Join Dr. Kelly to explore how his research on protein aggregation led to the discovery of tafamidis, the first effective drug for slowing the progression of a human amyloid disease. 📆Oct 22 | 9AM 📍Toronto & Online 🎟️Free 🔗https://bit.ly/InternationalSymposium2026 #GairdnerScienceWeek @scripps.edu

Scripps Research
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Scripps Research EVP Eric Topol is among 100 scientists featured in The New York Times' “Unknowns” project, which explores some of science’s biggest unanswered questions. His question: Can the human aging process be safely reversed?

ow.lyWhat Are the Biggest Questions in Science Today? 100 Scientists Weigh In.We asked 100 scientists about unsolved problems in their fields. They sent back provocations — on the origins of life, the possibilities for human progress and much more.
Scripps Research
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At the Scripps Research Biotech Innovation Summit, attendees will get an exclusive look at these emerging Scripps Research technologies and the scientists advancing them. 🗓️ Join us on Oct. 22, 2026 | Scripps Research, La Jolla 🎟️ View the program and request to attend: techsummit.scripps.edu/agenda/

Scripps Research
@scripps.edu

Here’s a sneak peek at tomorrow’s Discovery Day! Before you join us, check out these helpful details 👇 🎟️ Register on-site. 🚗 Complimentary parking is available. 🌮 Food trucks will be on site. 🧪 Enjoy activities for all ages! 📲 Find directions and FAQs at scripps.edu/discoveryday.

Scripps Research
@scripps.edu

Scripps Research scientists describe in Proceedings of the National Academy of Sciences an engineered small protein that binds immune receptor TLR4 within cell membranes and reduces signals that can drive inflammation, pointing to a potential drug target for inflammatory diseases.

ow.lyComputer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site - Scripps ResearchScripps Research scientists engineered a small protein that binds to the immune receptor TLR4 within cell membranes and reduces signals that can drive inflammation, pointing to a potential drug target for inflammatory diseases.
Scripps Research
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New global rankings place Scripps Research among the world’s top 200 institutions for regenerative medicine in the 2026 Nature Index supplement, which explores the discoveries driving the field and the challenges that could limit its progress. See the full list: https://ow.ly/AVMY50ZTjTq

Scripps Research
@scripps.edu

What’s ahead at the 2026 Biotech Innovation Summit? 🔬 Faculty spotlights on new technologies 🤖 AI-enabled Scripps Research discoveries 💊 Clinical-stage programs & digital clinical trials 💡 Industry and investor perspectives 🤝 Lean-In Sessions and interactive networking 🎟️ https://ow.ly/wsEu50ZGIao

Scripps Research
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Inside the Department of Integrative Structural & Computational Biology, scientists combine structural and computational methods to understand complex biological systems and pave the way for the next generation of drugs and precision therapies. 🔗 More: https://ow.ly/OcPx50ZNv6E

Scripps Research
@scripps.edu

We’re just a few weeks away from Discovery Day! 🔬 Explore hands-on science, watch live demos and see what it’s like to be a scientist for the day with Scripps Research scientists and graduate students. 📅 Oct. 3 | 10 AM–2 PM 📍 Scripps Research, La Jolla 🎟️ FREE tickets: https://ow.ly/OvoB50ZN2Hc

Scripps Research
@scripps.edu

In a new study, Scripps Research Prof. Jeffery Kelly and colleagues reveal a previously unknown way that the protein transthyretin (TTR) can unfold and break down. The alternative pathway is accessible to some TTR variants, particularly those that cause amyloidosis in the brain.

ow.lyScientists discover a new way that a disease-linked protein comes apart - Scripps ResearchNew findings from Scripps Research and the University of Illinois Urbana-Champaign reveal a previously unknown way that the protein transthyretin can unfold and break down, and how it may contribute to rare forms of amyloid disease.
Scripps Research
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Meet Assoc. Prof. Giordano Lippi, who leads a team at Scripps Research studying how microRNAs regulate gene expression during neuronal development and developing tools to precisely target disease-relevant microRNA–mRNA interactions.

Scripps Research
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It was a full house at our last Front Row! 👏 Scripps Research professor Ryan Shenvi shared how modern computation can help scientists narrow choices, reduce trial and error and find more efficient ways to make molecules. Watch the full talk and read the key takeaways: https://ow.ly/b7pi50ZEWXY

Scripps Research
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📣 Hey San Diego families! Discovery Day is back, and this year, we’re bringing the fun to the Scripps Research campus! Join us for a FREE, family-friendly day of hands-on science, exciting demonstrations and opportunities to meet our scientists and graduate students. 🎟️ https://ow.ly/QNXz50ZJBuM

Scripps Research
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Today’s the day! 🎉🔬Meet the team taking you behind the scenes of the Scripps Research NMR Core Facility! Join us LIVE today at 11 a.m. PT to see NMR technology in action, learn how scientists study molecules at the atomic level and ask your questions during our live Q&A. 📲 ow.ly/UKKm50ZzxvN

Scripps Research
@scripps.edu

Rehearsal complete! ✅ The NMR Live team is ready to take you behind the scenes of the Scripps Research NMR Core. Join us tomorrow, Friday, September 4, at 11 a.m. PT for a live tour, and bring your questions for our experts to answer during the Q&A! Watch live on YouTube: ow.ly/UKKm50ZzxvN

Scripps Research
@scripps.edu

Dyna-1, developed by Scripps Research professor Dorothee Kern and colleagues, predicts micro-to-millisecond protein dynamics in roughly 30 seconds. Published in Nature, the model was trained on missing NMR assignments to identify protein regions likely to move.

ow.lyWhere milliseconds matter: Scripps Research scientists build new ML model to predict protein movements essential for biological function - Scripps ResearchProtein dynamics in the micro-to-millisecond timescale once took months of experiments to characterize. Dyna-1 can now predict them in roughly 30 seconds.
Scripps Research
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ECG-CLIP outperformed other ECG foundation models when labeled data were limited, as few as 10 positive examples of a disease. The Lancet Digital Health study, led by Giorgio Quer, also found that ECG-CLIP better predicted future atrial fibrillation from ECGs displaying normal heart rhythms.

ow.lyNew AI algorithm could improve detection and prediction of heart diseases - Scripps ResearchScripps Research scientists have developed an ECG foundation model that can be adapted to new clinical tasks with less labeled data.
Scripps Research
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A new Nature Communications study from Jiang Zhu's lab reports a structure-guided strategy to stabilize influenza hemagglutinin (HA) trimers for nanoparticle vaccines. In preclinical models, the nanoparticles showed prolonged lymph node retention and elicited more robust immune responses.

ow.lyNew design strategy expands nanoparticle vaccine approach to influenza viruses - Scripps ResearchIn our September 9 Front Row lecture, Giordano Lippi shares what his lab is learning about the role that tiny molecules called microRNAs play in brain development. With new insights, his team is developing novel tools for potentially treating genetic disorders of the developing brain. Take a seat an…