Ina Sonnen

🎉 Our paper is out today in @science.org! How does the intestine maintain the right balance of cell types? We find that signalling rhythms matter! So proud of our three shared first authors, Sonja Weterings, @hiromuneeto.bsky.social & @jddeleede.bsky.social! 🔗 www.science.org/doi/10.1126/...

The @sonnenlab.bsky.social discovered a functional role for oscillation frequencies in keeping the gut cells in balance. They experimentally changed the frequency of Hes1 oscillations in intestinal organoids and showed that this altered cell-type composition.https://www.hubrecht.eu/cells-got-rhythm/

Funded places are available for early-career researchers at our Workshop on Bridging Scales and Disciplines to Understand Robust Development, 18-21 April 2027, organised by Mauricio Rocha Martins and Giulia Paci @giuliapaci.bsky.social Find out more and apply at www.biologists.com/workshops/ap...

I’m starting at the Hubrecht Institute at a new group leader from September. I will be hiring a PhD student through the PhD program ⬇️ If you, or anyone you know, is interested in theoretical biophysics, I will be very excited to hear from them — please send inquiries to my ISTA email for now :)

Funded places are available for early-career researchers at our Workshop on Bridging Scales and Disciplines to Understand Robust Development, 18-21 April 2027, organised by Mauricio Rocha Martins and Giulia Paci @giuliapaci.bsky.social Find out more and apply at www.biologists.com/workshops/ap...

There's still time to apply to be a 2026 @dev-journal.bsky.social Pathway to Independence fellow For those about to apply for their first independent academic position, the programme offers - mentoring - leadership training - profile rising - networking journals.biologists.com/dev/pages/pi...

Feb 1 deadline approaching for our @kitp-ucsb.bsky.social QBio summer course on Physical Principles of Morphogenesis in Plants and Animals. @streichan.bsky.social @maurazimmermann.bsky.social @maizel-lab.org @yusuke-mori.bsky.social @akankshi.bsky.social @nicolettapetridou.bsky.social

⏰ Deadline extension for #EESBioOsc ⏰ You now have until 14 January to submit your abstract for the EMBO | EMBL Symposium 'Biological oscillators: rhythms and synchronisation across scales'! 👉 s.embl.org/ees26-04-bl

Using fluorescence live imaging and an in vitro implantation model, we show that human embryo attachment begins with direct cell fusion via syncytin-2–MFSD2A interaction. With @hansclevers.bsky.social. Great work by @tnoordzij.bsky.social & @martinacelotti.bsky.social www.biorxiv.org/content/10.6...

Incredibly excited to receive an ERC Consolidator Grant. This recognition means a lot for what we’ve built so far and for what’s ahead. Thank you to all collaborators and supporters. Looking forward to getting this project going!

Don’t miss the @isscr.org Annual Meeting 2026 in Montreal. I will give a talk in the “Systematic and metabolic regulation of development” session. #ISSCR2026 www.isscr2026.org?gad_source=1...

Huge congrats to Dr. Sonja Weterings! Yesterday Sonja from my lab @hubrechtinstitute.bsky.social delivered an outstanding PhD defense. Her thesis explores how frequency encoding shapes cell type composition in the intestine. We’re so proud of her, and we’re going to miss her!

Ready to establish your own research group at the Hubrecht Institute for Molecular and Developmental Biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply! https://f.mtr.cool/jncxfqkuds

Just one month left to apply for the Hubrecht International PhD Program! This fully funded 4-year PhD offers the opportunity to join a high-profile lab in molecular & developmental biology, exceptional training, and mentorship from leading scientists. Apply before September 15 www.hubrecht.eu/hipp/

Please pread the word. We have just launched the Hubrecht International PhD Program (HIPP). Are you looking for a PhD position in molecular and developmental biology or related subject in an international, very supportive and collaborative environment? Then apply to the HIPP!! 👇

Thank you for the kind words and highlighting this milestone. I’m thrilled and honoured to have reached tenure. Big thanks to my lab, colleagues, mentors, friends and family who’ve supported me along the way. Excited to keep doing what I love - now with slightly more security.

It was fun reflecting on how my career path took me from a focus on cancer research to developmental biology, the urge to understand how development and tissue homeostasis work and how my time at the @biozentrum.unibas.ch contributed to this. Thank you, Katrin Bühler-Popowski, for the interview!

W2 TT W3 professorship in the Dynamics of Biological Systems at @uni-saarland.de - only a few days left to apply! (June 13) www.uni-saarland.de/fileadmin/up...

Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury. www.nature.com/articles/s41... A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka. 🧵1/14

I am just on my way to Switzerland and looking forward to a fun and exciting day at the Institute of Cell Biology in Bern tomorrow.

Thoughtful preview article by María Rodríguez Colman & @sonnenlab.bsky.social on recent papers from our lab and @jesseveenvliet.bsky.social lab! Grateful for their in-depth analysis of the papers and their big-picture perspective on the role of metabolism in development. doi.org/10.1016/j.st...

In preprints: robust segmentation clock outputs via cell cycle and synthetic coupling Here, @jorgelazaro.bsky.social and @ebisuyamiki.bsky.social discuss two #preprints looking into the mechanisms regulating somitogenesis through cell- and tissue-level couplings: doi.org/10.1242/dev....

Thanks for featuring my work with @sonnenlab.bsky.social and @marekvanoostrom.bsky.social in this thoughtful article!

We challenged our researchers to describe their work in 10 words or less. See how they did in this video!

Thank you for highlighting our preprint on the coordination between cell proliferation and the segmentation clock www.biorxiv.org/content/10.1...

Well done @virginiar-andra.bsky.social from our lab for being awarded the Best Poster Prize at the International Dutch Embryo Model Meeting today for our work on “Spatiotemporally resolved omics reveals dynamic antagonistic gradients” in embryo segmentation. Congratulations!

And what a talk that was!

I’m very proud of Sonja from my lab who presented our work on frequency encoding of cell-type composition in the small intestine as an invited speaker at Sy-stem 2025. www.biorxiv.org/content/10.1...

How do embryos ensure precise tissue patterning? It’s all about timing cell divisions! Our new preprint reveals how cell proliferation syncs with signaling oscillations to regulate precision of somite formation and growth. Check the full story: www.biorxiv.org/content/10.1...

As the IDEAS committee, we are dedicated to fostering an inclusive and supportive workplace at the Hubrecht Institute through initiatives on Inclusion, Diversity, Equity, Accessibility, and Social Safety. Check out our achievements from last year and our plans for 2025: www.hubrecht.eu/ideas-2024/

Don’t miss the inaugural Hubrecht Symposium, this year on the topic of developmental biology - morphogenesis and cell fate decisions. With Fiona Watt and Ben Simons as keynote speakers. There’s still time to register and submit an abstract for talks and posters. www.hubrecht.eu/hubrecht-sym...

I am really happy to announce the first Hubrecht Symposium on March 13th 2025! We will organize these yearly events on a specific topic in molecular and developmental biology to emphasize the importance of fundamental research for Dutch science. Free of charge! www.hubrecht.eu/hubrecht-sym...

Yesterday the first PhD student from the lab defended her thesis. Congratulations Dr. Yasmine el Azhar!

Ever wondered how stem cells ensure a balance between cell fates in the gut?⚖️Turns out, they’ve got rhythm!🎶Our latest research reveals that NOTCH-driven oscillations regulate stem/progenitor cell abundance and specify secretory subtypes. Check it out: biorxiv.org/content/10.1...