Theresa McKim

Theresa McKim

@tmckim.bsky.social

Assistant Teaching Professor | UNR Neuroscientist

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🧠🪰 Excited to share our paper in @elife.bsky.social detailing the synaptic connectome of the neurosecretory network in Drosophila. We mapped the hormone-releasing neurosecretory cells (NSCs) in the fly brain and their connectivity. 🧵https://doi.org/10.7554/eLife.102684

🧠🪰 Excited to share our paper in @elife.bsky.social detailing the synaptic connectome of the neurosecretory network in Drosophila. We mapped the hormone-releasing neurosecretory cells (NSCs) in the fly brain and their connectivity. 🧵https://doi.org/10.7554/eLife.102684

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🧠🪰 Excited to share our paper in @elife.bsky.social detailing the synaptic connectome of the neurosecretory network in Drosophila. We mapped the hormone-releasing neurosecretory cells (NSCs) in the fly brain and their connectivity. 🧵https://doi.org/10.7554/eLife.102684

View full thread

🧠🪰 Excited to share our paper in @elife.bsky.social detailing the synaptic connectome of the neurosecretory network in Drosophila. We mapped the hormone-releasing neurosecretory cells (NSCs) in the fly brain and their connectivity. 🧵https://doi.org/10.7554/eLife.102684

View full thread

Most NSCs have dendrites in the taste area of the brain, yet their input is mostly indirect. Gut (enteric) neurons have the strongest influence on NSCs. What you’ve ingested seems to matter more than what you’ve tasted.

NSCs also receive input from descending neurons, which suggests hormones and movement are coordinated. NSC output is sparse and comes mostly from corazonin (CRZ) cells onto DNg27. Silencing either cell type reduces egg-laying.

🧠🪰 Excited to share our paper in @elife.bsky.social detailing the synaptic connectome of the neurosecretory network in Drosophila. We mapped the hormone-releasing neurosecretory cells (NSCs) in the fly brain and their connectivity. 🧵https://doi.org/10.7554/eLife.102684

We identified 80 NSCs in the FlyWire connectome, and similar neurons in BANC and maleCNS connectomes. They fall into 10 classes based on the neuropeptide they produce, and we propose a unified naming scheme for them.

Who controls the hormones? DH44 cells (the fly homolog of a stress hormone) receive input from many of the same neurons that also connect to other NSC classes. They are a likely hub for coordinating physiology and behavior.

Great opportunity to learn about resources and gain support in bringing cutting edge science and methods into the classroom!

allen institute@alleninstitute.org

Teach neuroscience to undergraduates? Learn how to incorporate our connectomics data into your courses! 🧠 "Incorporating open connectomics data into teaching neuroscience" 🗓️ July 23-24 🛫 Travel funds available ⏳ Apply by Feb. 2: https://bit.ly/3LAfOdy #neuroskyence

Apply to join us! 🧠👩‍💻

allen institute@alleninstitute.org

Our python workshop for educators is returning! 💻 No prior coding experience needed. ✈️ Travel, meals, & stipend included. Apply by February 2 at: https://alleninstitute.org/events/educator-coding-workshop-2026/ #iTeachBio

Looking forward to facilitating this again! 🧠 Apply to join us for this workshop 👩‍💻

allen institute@alleninstitute.org

Our python workshop is returning! Undergraduate educators, join us on July 27-30 for "Coding with Allen Institute Data." No prior coding experience needed. Travel, meals, & stipend included. Apply by Feb. 2 at: https://alleninstitute.org/events/educator-coding-workshop-2026/ #iTeachBio #EduSky

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