Violet Liu

1/ A deep brain region known as the A13 plays a central role across a diverse range of behavioural functions (in rodents). To our knowledge, no human homologue has been identified to date. In this #preprint, we map the human A13!🎯 🔗 www.biorxiv.org/content/10.6...

7/ Finally, we performed a gradient-based analysis, identifying a principal rostral-caudal axis of organization for the ZI, within which the A13 emerges as a local molecular specialization.

1/ A deep brain region known as the A13 plays a central role across a diverse range of behavioural functions (in rodents). To our knowledge, no human homologue has been identified to date. In this #preprint, we map the human A13!🎯 🔗 www.biorxiv.org/content/10.6...

5/ Thus, we sought confirmation. For an independent tissue specimen, we acquired 15.2T MRI then histology, confirming a TH+ cluster in the ZI. Further to this, we found the distribution was more spatially specific, and restricted to dorsal to the H2 field of Forel.

1/ A deep brain region known as the A13 plays a central role across a diverse range of behavioural functions (in rodents). To our knowledge, no human homologue has been identified to date. In this #preprint, we map the human A13!🎯 🔗 www.biorxiv.org/content/10.6...

3/ We generated gene expression maps from the @alleninstitute.org Human Brain Atlas, identifying a TH-enriched ZI subregion, consistent with the expected (relative) location of the rodent A13.

1/ A deep brain region known as the A13 plays a central role across a diverse range of behavioural functions (in rodents). To our knowledge, no human homologue has been identified to date. In this #preprint, we map the human A13!🎯 🔗 www.biorxiv.org/content/10.6...