Wafik S. El-Deiry, MD, PhD, FACP

Wafik S. El-Deiry, MD, PhD, FACP

@weldeiry.bsky.social

Physician-Scientist Oncologist, Director Legorreta Cancer Center, Associate Dean, past Faculty Exec Cmte member, Brown Univ, ACS Professor, Chair, WIN Consortium in Precision Oncology, Entrepreneur, Boat Captain, joined Nov 16 ‘24 Pubs: tinyurl.com/s98xg3u

804 followers190 following3.6K posts

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Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

On 10-26-2024 I was at Brown University Family Weekend on College Green to share exciting progress at #LegorretaCancerCenter. As a colon cancer doctor my message was to make sure you get your screening colonoscopy to prevent colon cancer as this could save your life. www.tiktok.com/t/ZTYLaQo9J/

tiktok.comI’m here at @BrownUniversity Family Weekend on the College Green to speak with you about exciting developments at the #LegorretaCancerCenter over the last few years. As a colon cancer doctor my messa...TikTok video by weldeiry
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

First-line fecal microbiota transplantation for the management of immune checkpoint inhibitor-mediated diarrhea and colitis www.cell.com/cell-reports...

cell.comFirst-line fecal microbiota transplantation for the management of immune checkpoint inhibitor-mediated diarrhea and colitisWang et al. report the efficacy of a preliminary cohort of patients who receive first-line fecal microbiota transplantation for the management of immune-mediated diarrhea and colitis with multi-omics ...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Inhibitory circuits restrain adult glioma progression by suppressing calcium-driven oncogenic programs www.cell.com/neuron/abstr...

cell.comInhibitory circuits restrain adult glioma progression by suppressing calcium-driven oncogenic programsUesaka et al. show that inhibitory brain circuits can suppress adult glioma growth by limiting tumor calcium signaling and downstream growth programs. The study reframes glioma progression as a balanc...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

A targetable dependency on nonsense-mediated decay for cellular homeostasis and immune control in small cell lung cancer link.springer.com/article/10.1...

link.springer.comA targetable dependency on nonsense-mediated decay for cellular homeostasis and immune control in small cell lung cancer - Molecular CancerSmall cell lung cancer (SCLC) is one of the most aggressive malignancies, characterized by rapid metastatic dissemination and poor overall survival. Despite harboring excessive alterations, expectedly...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Early detection of invasive lung cancer and multiorgan metastasis by a collagen-targeted protein MRI contrast agent www.science.org/doi/10.1126/...

science.orgEarly detection of invasive lung cancer and multiorgan metastasis by a collagen-targeted protein MRI contrast agentLung cancer with multiorgan metastasis remains the leading cause of cancer death. Current CT imaging and biopsy are suboptimal for detecting early tumors or subclinical metastases. We address this gap...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Top AI leaders unite to warn the technology is advancing too fast Dario Amodei, Sam Altman and Elon Musk, long at odds with each other, found common ground in calling for a slowdown in AI amid mounting fears about its dangers. www.washingtonpost.com/technology/2...

washingtonpost.comTop AI leaders unite to warn the technology is advancing too fastDario Amodei, Sam Altman and Elon Musk, long at odds with each other, found common ground in calling for a slowdown in the advancement of AI amid mounting fears about its dangers.
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Targeting tumor-associated macrophages using mRNA lipid nanoparticles for cytotoxic T lymphocyte–mediated cancer immunotherapy www.science.org/doi/10.1126/...

science.orgTargeting tumor-associated macrophages using mRNA lipid nanoparticles for cytotoxic T lymphocyte–mediated cancer immunotherapyThe immunosuppressive tumor microenvironment (TME) remains one of the main obstacles that limit responsiveness to immunotherapy. Recently, lipid nanoparticles carrying messenger RNA (mRNA) have emerge...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Political world erupts as AI researchers warn of ‘extinction’ threat Anthropic has built its reputation as the safety-minded AI company. But some of its own researchers fear the race it has joined could end with humanity’s destruction. www.washingtonpost.com/technology/2...

washingtonpost.comPolitical world erupts as AI researchers warn of ‘extinction’ threatAnthropic has built its reputation as the safety-minded AI company. But some of its own researchers fear the race it has joined could end with humanity’s destruction.
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Attended, as Secretary of the Faculty, the first university-wide faculty meeting for the academic year at on Brown’s College Hill campus in Providence, RI. The meeting had a celebratory tone with newly appointed and promoted faculty. Exciting year up ahead at @BrownUniversity which brings me hope.

Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

“But if you're a researcher and you just watched this happen, I don't think you'd keep your best ideas inside someone else's product.” OpenAI fought dirty on career-making math problem, says NYU mathematician techcrunch.com/2026/09/08/o...

techcrunch.comOpenAI fought dirty on career-making math problem, says NYU mathematician | TechCrunchThere is a $1 million bounty for the first person providing a solution to the Navier-Stokes existence and smoothness problem.
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Laser Interstitial Thermal Therapy for Brain Tumors: A Prospective Multicenter Analysis of Patients From the LAANTERN Study ascopubs.org/doi/10.1200/...

ascopubs.orgLaser Interstitial Thermal Therapy for Brain Tumors: A Prospective Multicenter Analysis of Patients From the LAANTERN StudyPURPOSELaser interstitial thermal therapy is a surgical tool used to ablate brain tumors, radiation necrosis, and epileptic foci. Data from the LAANTERN prospective multicenter registry (ClinicalTrial...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

It is notable to hear Dr. Ashish Jha say he now believes the COVID pandemic was most likely the result of a lab leak. And it is also important to hear him say that gain-of-function research is a global issue that should be addressed as such. I fully agree. x.com/ashishkjha/s...

x.comAshish K. Jha (@ashishkjha) on XOn @CNNSOTU with @DanaBashCNN this morning. I said three things: 1. Political leaders are accountable for public health decisions, not the scientists who advise them 2. The vaccine-autism question h...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

I will disconnect at this time. Social Media takes too much of my precious time. Any time I have I would like to invest in science and medicine. And any posts will be strictly focused on discoveries and advances in cancer research and oncology. Thank you.

Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Nearly a decade ago in 2017 I wrote about needed improvements to electronic health record systems but in 2026 we still scan faxed records into an EHR that is often very difficult to access including pathology images that are still not electronically accessible. www.linkedin.com/pulse/what-d...

linkedin.comWhat does a better EHR look like?I tweeted recently "It is sad that electronic health records are designed around billing, not optimal patient care, utility, provider efficiency or satisfaction" (https://twitter.com/weldeiry/status/9...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Save the Date for 2026 @WIN_Consortium Symposium in Rhode Island October 2-3, 2026. @Dr_R_Kurzrock @AACRPres @realrickpazdur @SewantiLimaye @DrRoyHerbst @LussierY @LiaTsimberidou @bcarneiro7 @LiangChengMD @RueterJens @alshamsi2000 @JiaJennyLiu @VivekSubbiah @billdahutmd @DrJoannSweasy

Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Voluntary healthcare cost limits aren’t working. Should Rhode Island’s insurers face sanctions? As spending skyrockets, health insurance commissioner report recommends adding teeth to spending growth targets rhodeislandcurrent.com/2026/05/18/v...

rhodeislandcurrent.comVoluntary healthcare cost limits aren’t working. Should Rhode Island's insurers face sanctions? • Rhode Island CurrentPer-person spending on hospital services, prescription drugs, and long-term care rose 9.1% from 2023 to 2024, nearly twice as fast as the 5.1% state target, according to a new report published Monday ...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Ensitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts “Ensitrelvir administered to household contacts of a patient with Covid-19 within 72 hours after symptom onset in the index patient was effective in preventing Covid-19 in the contacts.” www.nejm.org/doi/10.1056/...

nejm.orgEnsitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts | NEJMEnsitrelvir, an oral inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3C-like protease, is approved in Japan for the treatment of mild-to-moderate coronavirus disease 2019 ...
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry.bsky.social

Ended for futility, BIOMEDE validated prognostic biomarkers as well as informative theranostic biomarkers for future DIPG trials👇 Targeted therapies plus radiotherapy for diffuse intrinsic pontine glioma: the randomized phase 2 BIOMEDE trial www.nature.com/articles/s41...

nature.comTargeted therapies plus radiotherapy for diffuse intrinsic pontine glioma: the randomized phase 2 BIOMEDE trial - Nature MedicineIn a biomarker-driven trial evaluating radiotherapy with erlotinib, everolimus or dasatinib in patients with newly diagnosed diffuse intrinsic pontine glioma, the primary endpoint of overall survival ...