WGDip

WGDip

@wgdip.bsky.social

Reappraising the role of whole genome duplication and rediploidisation in eukaryotic evolution. Funded by BBSRC Strategic Longer and Larger scheme. Check out our website for information about the project, team and more! https://www.rediploidisation.org/

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This time last year marked the beginning of the #WGDip project! 🥳 Are you interested in eukaryotic evolution & whole genome duplication? So are we! Find out more about who we are and what we are doing on our website: www.rediploidisation.org 🧪🧬 @ukri.org #BBSRC #sLoLa

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WGDip@wgdip.bsky.social

We are excited to announce the 'official' start of our BBSRC funded sLoLa project, where we aim to uncover the role of rediploidisation in shaping evolution after genome duplication events across the tree of life! Find out more: www.rediploidisation.org vet.ed.ac.uk/roslin/news-... #WGDip #BBSRC

More on #WGDip participation at the International Polyploidy Conference 2026! Dan Macqueen discussed rediploidisation's role in making new genes🧬, while Drew Larson & Kevin Bird shared insights on rediploidisation following WGD in the salmonids 🐟 and apple tribe🍎.

Big congratulations to our ECRs who shared their work through poster presentations at #IPC2026! Great science on display from Annabelle Knutson, Brianna Banting, Emily Haley, Kevin Bird, Morgane Milin & Zoe Vance. Thank you for sharing your work & sparking great conversations #Polyploidy #ECR #WGDip

What an incredible few days at the International Polyploidy Conference 2026! 🧬 Great to have discussions with such a fantastic #polyploidy community! Huge thanks to the organizers, speakers, and everyone who presented for making it such a great meeting. #WGD #IPC2026

Thanks @luohaoxu.bsky.social for presenting at #WGDip’s science forum. Using snow carp as a model, he argued that chromosome fusions often initiate rediploidisation after autopolyploidy. Featuring a haplotype-resolved assembly with 443 chromosomes (20n!) & insights into polyploid sex determination.

Huge congratulations to #WGDip project partner Aoife McLysaght for receiving the Community Service Award from @official-smbe.bsky.social. This recognises Aoife’s outstanding contributions and commitment to building stronger research communities through collaboration, leadership, and generosity. 👏

The #WGDip team really enjoyed #SMBE2026! We shared posters from Zoe Vance, Anthony Redmond and Lucas Freitas, plus flash talks from Róisín Long and Lukasz Niezabitowski. Great to see growing interest in rediploidisation with lots of interesting chats! Thanks to the organisers for an epic meeting! 👏

WGDip reposted

Showing some @wgdip.bsky.social work at #SMBE2026! Swing by poster 217 for a chat about whole genome duplication in yeast and why many of the duplicated genes appear to have been created at different points in time

Congrats to the Oxford team including #WGDip team member Peter Holland @peterhox.bsky.social on their @nature.com paper on the importance of WGDs in the development of vertebrate brains🧠, showing that resulting ohnologues continued to support cell-type evolution & development of vertebrate brains 🧪

🌊Happy #WorldOceanDay! 🌊 Today we reflect on one of the smallest 🔬 eukaryotes studied by #WGDip, diatoms! These tiny single-celled, photosynthetic algae found across aquatic environments play an outsized role in our planet's health...

...Diatoms contribute an estimated 20% of the world’s oxygen, support marine food webs & are indicators of ecosystem health. Encased in intricate, glass-like silica shells, each species is uniquely beautiful. These tiny but powerful diatoms remind us that ocean health depends on life at every scale!

#WGDip hosted @ferdix.bsky.social (University College London) who reviewed the emergence of chaetognaths & priapulids. Discussing gene duplication, cryptic WGD, the impact of gene loss & maintenance or dispersion of ancestral bilaterian linkage groups & the emergence of new cell types & morphologies

Happy #BiologicalDiversityDay! 🌍🌿🐟🐌 #WGDip explores how WGD & rediploidisation have shaped eukaryotic diversity through evolutionary time. By studying genomes from a wide range of organisms, we aim to understand how these processes contributed to the extraordinary diversity of life we see today!

Angiosperms have a complex evolutionary history shaped by WGD, with different plant groups experiencing these events at different times & frequencies! #WGDip is looking at the Maleae tribe. This fascinating group includes familiar favourites like apples, pears & quinces 🍏🍐🍎

#WGDip is exploring the genomic history of species across the eukaryotic tree of life. This includes the flowering plant order Ericales - an incredibly diverse lineage with over 12,000 species! Chances are, you already know (and love) some of its members… like tea, kiwi, and blueberries! 🍵🥝🫐

Congrats to @luohaoxu.bsky.social & team for revealing the role of chromosome fusions in initiating asynchronous rediploidisation in autotetraploid snow carp. Featuring #WGDip lead Dan Macqueen as co-author. A landmark study in our ongoing understanding of rediploidisation! @nature.com @ukri.org 🧪

luohaoxu.bsky.social@luohaoxu.bsky.social

Thrilled to share our recent publication in @nature.com. We discovered that snow carps experienced a relatively recent whole genome duplication #WGD, making this lineage an ideal lineage to study #rediploidization. www.nature.com/articles/s41...

Today we celebrate #NationalDNADay and reflect on how far genomic science has come, from discovering the structure of DNA🧬 to the completion of the Human Genome Project🌐. Without these insights, modern evolutionary genomics projects like #WGDip wouldn’t be possible! 🧪

Happy #worldbookday!📚 #WGDip was inspired by Susumu Ohno’s "Evolution by gene duplication”, published 56 years ago, before the modern era of genomics. His book argued for the central importance of duplicating both individual genes & whole genomes as 'fuel' for great leaps in biological evolution...

Ohno also understood the importance of rediploidisation! A reminder that powerful ideas in books can spark new scientific journeys! 📖🧪

Happy #EarthDay! 🌍 As evolutionary biology researchers, we’re reminded every day that the diversity of life on Earth is the result of millions of years of evolution, adaptation, & resilience. Today we acknowledge the importance of protecting the natural world that makes this research possible! 🐌🐟🌱

Our ECRs recently travelled to Dublin for two fantastic days filled with science, collaboration, and a bit of well-earned fun! #WGDip #ECR

Can you identify this unusual purple-flowered plant in bloom at the @thebotanics.bsky.social?🔎🪻 This plant has no leaves & cannot photosynthesise. It's an important early spring flower, especially for bees🐝. Its nectar is high in ammonia, making it unsavoury for other pollinators & nectar robbers.

This parasitic plant, Lathraea clandestina, is being studied by MRes student Annabelle Knutson, as part of our work on genome duplication in #WGDip. Lathraea experienced a genome duplication🧬 & this may have facilitated its parasitic adaptations! #wildflower #parasiticplant #WildflowerHour 🧪

🌳🌲Today we celebrate #InternationalForestDay & their incredible diversity!🌲🌳 Willows (Salicaceae) are a remarkable family - with a well-documented ancestral WGD event - that includes trees with huge value for people & the planet. For centuries, willows have been used in basket weaving🧺, ...

...paper production📃, & medicine💊. Ecologically, they’re powerful allies in environmental restoration, helping absorb pollutants & stabilise riverbanks. From practical uses to protecting ecosystems, willows show how vital woodlands are to both people & the environment. 🌱🧪#InternationalDayofForests

Hear from Jack, a Science Engagement Manager at the Wellcome Sanger Institute. He hopes that #WGDip will engage the public with the DNA data revolution & explain why large-scale datasets are key to answering some of science’s toughest questions! 🧬🌍 @sangerinstitute.bsky.social

🧪A recent article in Science Advances revisits long-debated WGD events during early seed plant evolution. Using dosage-sensitive genes as markers of WGD, the authors found little support for an angiosperm-specific WGD, and strong evidence for a single WGD shared by all seed plants. buff.ly/W0hQYno

buff.lyRevisiting ancient whole-genome duplications in the seed and flowering plants through the lens of dosage-sensitive genesDosage-sensitive genes suggest no ancestral angiosperm WGD.

The #WGDip team has created videos spotlighting our amazing researchers and team members. We asked about their roles, what excites them, and the impact they hope WGDip will have. Stay tuned over the coming weeks and check in regularly to hear their stories!

The #WGDip team kicked off 2026 with an in-person meeting hosted at the Wellcome Genome Campus✨. We had a fun, science-packed two days that strongly advanced our plans to work together across both our research and science outreach plans - it's going to be an exciting year!

📢Meet the team! Andrea Mazgaleva is a Project Coordinator in the Tree of Life Programme. For the #WGDip project, Andrea will be overseeing the production of 15 chromosome-level reference genomes through the ToL pipeline. 🧬💻

🧪New preprint from WGDip lead Dan Macqueen with collaborators from the AQUA-FAANG project www.aqua-faang.eu, including WGDip team member Manu Kumar Gundappa. Exploring regulatory evolution following the autotetraploid WGD ancestral to salmonids (featuring rediploidization!) doi.org/10.64898/202...

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bioRxiv Evolutionary Biology@biorxiv-evobio.bsky.social

Salmonids reveal principles of regulatory evolution following autotetraploidization https://www.biorxiv.org/content/10.64898/2025.12.18.695160v1

From all of us on the #WGDip team, we’re wishing you a joyful, restful, and cosy holiday season ❄️🎄 We can’t wait to see what the year ahead has in store! 🎉

📢Meet the team! Finn McHale is a Research Assistant from the University of Oxford. His recent Master's project investigated WGD of snails and slugs!🐌 Now he's looking for signs of delayed rediploidisation in other invertebrate genomes with #WGDip Read Finn's paper here:📝 doi.org/10.1002/jez....