Richard White

The ZDM19 meeting in Oxford is coming up soon! We have a great list of speakers, lots of early career researcher events, and an amazing location. Registration is open now but early bird pricing will end soon - so please register as soon as possible! www.zdmsociety.org/zdm19-regist...

x.comCSIR-IGIB on X: "In the first episode of the #MeetThePI series, @shruthy_suresh shares her journey into science, the inspirations that shaped her career, and her vision for the road ahead. Get a glimpse into the person behind the research and the science driving her lab at IGIB. 🔬✨ Click the https://t.co/UNT8zNdz8T" / XIn the first episode of the #MeetThePI series, @shruthy_suresh shares her journey into science, the inspirations that shaped her career, and her vision for the road ahead. Get a glimpse into the person behind the research and the science driving her lab at IGIB. 🔬✨ Click the https://t.co/UNT8zNdz8T

21 May

The true highlight of an academic career is seeing trainees find their own path. My former postdoc @shruthysa.bsky.social is such a passionate scientist, and her institute made a profile about her and the work she is doing on metastasis. She is so inspiring - check it out: x.com/IGIBSocial/s...

20 Nov 2025

Pleased that I have been awarded a Professorship grant from the UK Academy of Medical Sciences - to support new directions for the lab using #zebrafish models of #melanoma. And congrats to the other awardees Philip Shaw from King's College London and Mark Dewey from Oxford.

Academy of Medical Sciences@acmedsci.bsky.social

Congratulations to Professorship awardees Prof Phillip Shaw, Prof Marc Dewey and Prof Richard White 🎉 With international expertise from the US and Germany, the awards support their work across major health issues and ensure global perspectives in UK research 🌎🔬 👉 bit.ly/43E9tnn

doi.orgCompression causes cancer cells to start spreadingThe switch between proliferation and invasion is triggered by mechanical force.

4 Sept 2025

A really nice Research Briefing on Miranda's @mrndhntr.bsky.social paper. Check it out here: doi.org/10.1038/d415...

Richard White@whitefishlab.bsky.social

Cancer cells are notoriously plastic, but what triggers the changes in cell state? In our new Nature (@nature.com)‬ paper, Miranda Hunter (@mrndhntr.bsky.social‬) found that mechanical pressure is a key to this switch. Check it out here: go.nature.com/47iwDm2

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My favorite part? This was driven by Miranda’s curiosity. She noticed that the cells in the tumor looked squeezed, and then followed the trail all the way to mechanism and implications.

And a special thanks to our many collaborators and funding from the @melanomaresearch.bsky.social‬, @NIH_CommonFund, @theNCI and @ludwigcancer.bsky.social‬

Using a combination of #zebrafish and human #melanoma cells, she discovered that when cells are mechanically confined, this turns up chromatic factors like HMGB2, rewiring them to be more invasive and drug resistant.

The implications are pretty clear: while DNA mutations and chemical signals from the environment are important, physical pressure is just as important in letting cancer cells take on new behaviours.

smrcongress.orgSociety Melanoma Research Congress

8 July 2025

Hey everyone - the annual SMR #melanoma meeting in beautiful Amsterdam is coming up. Always a fantastic lineup of research spanning basic, translational and clinical. We also have a great trainee "pre-SMR" meeting, with top talks being selected for the main meeting. Join us! smrcongress.org

Daniel Peeper Lab@peeperlab.bsky.social

The SMR 2025 Annual Congress (Amsterdam Oct 25-28) covers basic, preclinical & translational melanoma research of international top investigators. It is a very enjoyable conference with top faculty and now improved with ample opportunity for young investigators to network. Join us! smrcongress.org

smrcongress.orgSociety Melanoma Research Congress

21 May 2025

Zebrafish people! The @ZDMSociety annual meeting is in Boston this year, with a great lineup. Abstract submission is closing May 27th. Go register now for this always fun conference #zebrafish www.zdmsociety.org/zdm18-home

ludwigoxfordepicancer2025.my.canva.siteLudwig Oxford EpiCancer Symposium 2025Ludwig Oxford are delighted to welcome you to join us for the Ludwig Oxford EpiCancer Symposium, held on the 26th and 27th June 2025 at Rhodes House, Oxford

22 Feb 2025

Spots still available for the Cancer epigenetics meeting hosted by @ludwigcancer.bsky.social at Oxford @ox.ac.uk. Amazing lineup of speakers including Craig Thompson, Scott Lowe, Caroline Bartman and many others. Info here - register soon!: ludwigoxfordepicancer2025.my.canva.site

10 Feb 2025

For #zebrafish people - we have a joint @ZDMSociety @InfoIzfs webinar focused on single-cell tech coming up on February 20th. Featuring Yinan Wan, Jialin Liu and Loic Royer. Register here: www.izfs.org/education/we...

nature.comOrthogonal RNA replication enables directed evolution and Darwinian adaptation in mammalian cells - Nature Chemical BiologyAn orthogonal alphaviral RNA replication system with chemically inducible control of RNA mutagenesis enables RNA-based directed evolution in mammalian cells.

6 Jan 2025

Synthetic biology meets Darwinian evolution. This new paper shows how you can do directed "evolution campaigns" using mutation of RNA rather than DNA: www.nature.com/articles/s41.... Could we do this in vivo in #zebrafish ?