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I am very proud of lead author Tara Arbab for completing this most recent manuscript from the lab! --> Intracranial electrophysiological biomarkers of compulsivity in OCD. www.nature.com/articles/s44...
WilluhnLab
@willuhnlab.bsky.social
A bunch of passionate neuronerds studying the brain origins of reinforcement learning and compulsive behavior at the Netherlands Institute for Neuroscience. Dopamine, serotonin, basal ganglia, PFC, DBS. https://nin.nl/research/researchgroups/willuhn-group/
472 followers279 following27 posts
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I am very proud of lead author Tara Arbab for completing this most recent manuscript from the lab! --> Intracranial electrophysiological biomarkers of compulsivity in OCD. www.nature.com/articles/s44...
WilluhnLab reposted
🚨 My new paper is out in CABN! 🚨@psychonomicsociety.bsky.social Do human 'habit' tasks measure the same thing? In this study, we compared the most commonly used paradigms, "Outcome Devaluation" & "Response Remapping", under matched training + time pressure 🧠⌛ link.springer.com/article/10.3...
WilluhnLab reposted
WilluhnLab reposted
I'm hiring a postdoc to start in summer/fall 2027! My lab uses computational social & cognitive science methods to explore how tech shapes knowledge & power: www.crockettlab.org You can submit an application here: apply.interfolio.com/195297. Review of apps starts Nov 20. Please share!
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Dopaminergic Medication Improves Force Control and Modifies Motor Unit Activity During the Steadiest and Least Steady Periods in Parkinsons Disease https://www.biorxiv.org/content/10.64898/2026.10.16.758033v1
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Oh, oh my. I need to go through this closely, and as noted earlier NN has a history. But my first read is wow www.nature.com/articles/s41...
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📸 Looking back on the #BernsteinConference 2026 The conference photo gallery is now online! Take a look and relive the highlights 👉 buff.ly/Mv2PKVI #BernsteinNetwork #Neuroskyence 🧠 📈
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⚠️ Final chance to apply for Brain Awareness Week grants! The applications will close TOMORROW! 📢 Organise your own outreach event 🧠 Facilitate public engagement with neuroscience 💶 Funding of up to EUR 1,000 for projects based in Europe 🔗 Apply today: buff.ly/gr0x8hp @danafoundation.bsky.social
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China is on a trajectory to lead the world in science, a development that will reshape technological advancement, innovation and the balance of global power go.nature.com/4yT9FwA
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Faculty job opening in Neurodevelopment / Neuroregeneration at UT - San Antonio Please spread the word! www.nature.com/naturecareer...
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mCranberry: A rationally engineered monomeric red fluorescent protein with 85% quantum yield by Premashis Manna and team: www.biorxiv.org/content/10.6...
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For this new series, @thetransmitter.bsky.social evaluated whether neuroscience still needs nonhuman primates & if alternative models are ready to replace them. Over the next few weeks, four articles will detail what we found—and what the loss of nonhuman primate research would mean. bit.ly/4AWPX4l
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WilluhnLab reposted
Replying to @lintianphd.bsky.social
Thank you to @tpatriarchi.bsky.social for introducing my keynote talk, and thanks to @willuhnlab.bsky.social & Paul Phillips for inviting me and for organizing a thoughtful & energizing meeting. Looking forward to MMiN 2028!
Large-effect OCD risk genes! Exciting to see this paper published. www.nature.com/articles/s41...
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🚨 Job alert 🚨 Our department @vuamsterdam.bsky.social is hiring an Assistant Professor in Cognitive Neuroscience! Join our lovely community here in beautiful Amsterdam! 🧠🔥 Deadline: October 15 Apply: workingat.vu.nl/vacancies/as...
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🥳 Super excited to share our lab's first preprint, led by @hungyun.bsky.social "Distinct tasks engage shared neural subspaces in human hippocampus and anterior cingulate cortex" www.biorxiv.org/content/10.6... 🧵(1/9)
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New paper from the BCM Neurosurgery research team! "Neural basis of compositional control" led by @assiachericoni.bsky.social and @justfineneuro.bsky.social ! 🧵 www.nature.com/articles/s41...
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What if we could detect ahead of time when MH symptoms will escalate? In our newest paper led by @aleyamarzuki.bsky.social we show that drops in confidence precede #OCD symptoms! Our findings suggest: Momentary cognitive task assessments could change when and how we deliver interventions! Details 👇🏼👇🏼
📢 Our paper is now out in @natcomms.nature.com! www.nature.com/articles/s41... We know that symptoms of OCD fluctuate substantially. But what are the exact conditions that precede symptom escalations? We found evidence for metacognitive processes being a key antecedent. 1/
WilluhnLab reposted
WilluhnLab reposted
light-activated tetanus neurotoxin (LATeNT) by the @aliceyting.bsky.social lab. Includes a comparison with the light-switchable PdCO (www.nature.com/articles/s41...), showing a long lasting inhibition for 1h hour post illumination. www.nature.com/articles/s41...
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Dopamine dips during unrewarded actions promote punishment-resistant reward seeking https://www.biorxiv.org/content/10.64898/2026.08.01.742224v1
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Adolescent stress recruits a latent amygdala-dopamine circuit to drive punishment-resistant reward-seeking https://www.biorxiv.org/content/10.64898/2026.07.29.741478v1
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Dorsomedial striatal dopamine ramps down during interval timing https://www.biorxiv.org/content/10.64898/2026.08.01.742215v1
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Computational and causal dissociation in primate striatum during value-guided decision-making https://www.biorxiv.org/content/10.64898/2026.07.29.741388v1
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WilluhnLab reposted
Methylphenidate enhances or impairs the cognitive control of Pavlovian bias depending on working memory capacity
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Artificial intelligence is a democratizing force for those without graphic-design experience, as long as it is used conscientiously go.nature.com/3RtnKQM
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I am happy to announce my very first senior author paper! Serotonin is known to abolish UP-DOWN state dynamics, which occur during sleep and anesthesia. There are several outstanding questions: What happens at short latencies? How widespread across the brain is it? 🧠 www.biorxiv.org/content/10.6...
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Ventral tegmental area dopamine neuron activity mediates multi-valent outcomes during decision making under risk of punishment https://www.biorxiv.org/content/10.64898/2026.07.14.738459v1
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Distinct Orbitofrontal Feedback Signals Shape Sensory Behavioral Strategies during Flexible Learning https://www.biorxiv.org/content/10.64898/2026.07.15.737076v1
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Can we trust subthalamic local field potential? Geometrical and dynamical factors constraining the interpretability of extracellular recordings https://www.biorxiv.org/content/10.64898/2026.07.08.737284v1
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The unique value of zero prediction errors in reinforcement learning https://www.biorxiv.org/content/10.64898/2026.07.13.738284v1
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Nature research paper: Fourier pixels for bidirectional light control go.nature.com/4ao2xOG
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⏰ Last-minute reminder! Only 48 hours left to submit your Poster abstracts and Travel Grant applications for the #BernsteinConference 2026! 🗓️ Deadline: July 1 All information 👉 bit.ly/4rQowo6... #CompNeuro #Neuroskyence #BernsteinNetwork
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Congratulations to Felice Veen from the @willuhnlab.bsky.social on receiving the Carl Storm Fellowship to attend the Gordon Research Conference on the Frontal Cortex this August! We are so excited! #neuroscience #GRC-FrontalCortex
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WilluhnLab reposted
Save the date: the 3rd biennial #engramsandensembles conference will be held from May 12 - 14, 2027 at @tcddublin.bsky.social 🧠🌐📈
Slán go fóill - we look forward to welcoming you all back to Dublin for the 3rd installment in May 2027 #engramsandensembles
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Mu opioid receptor neurons in the habenula drive naloxone-induced aversion and withdrawal in mice, and pharmacological blockade of the co-localized orphan receptor GPR139 attenuates both somatic and affective withdrawal symptoms.
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We're hiring a PhD Student! Under supervision of @sergedumoulin.net, you will investigate whether individual brain folding patterns reflect computational principles that optimize neural communication and brain organization. Learn more and apply on our website: nin.nl/vacancies/ph...
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Want your mice to learn your task faster? 🐭 According to this paper giving a huge reward (10x typical size) in a subset of trials strongly shortens training times: www.science.org/doi/10.1126/...
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🔥 Our latest work is state of the art 3D pose estimation, with video analysis from a single camera! 🎥 Just train with 3D data, and then only 1 camera is needed! 🖤 Presented this week at #CVPR2026 by lead author Ti Wang! Please repost🩵🙏🏼 xiu-cs.github.io/FMPose3D/ arxiv.org/abs/2602.05755
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The @thetransmitter.bsky.social featured an awareness campaign by the Oregon Voices for Biomedical Research, alerting to the impact that the closure of the #ONPRC could have on biomedical research, amid negotiations to transform the facility into an animal sanctuary. 🔗 shorturl.at/IGBYA #NHP #US
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At #EICSummit2026, Prof. Amunts showcased how the HBP legacy continues through EBRAINS: SpiNNaker, The Virtual Brain, brainfm on JUPITER, NEST Simulator. From frontier research to lasting impact in neuroscience, healthcare, AI and next-generation computing. More: ebrains.eu/news-and-eve...
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🏆 Congratulations to the Early Career Training Programme awardees for #FENS2026! 🧠 #FENS is excited to share the researchers selected to visit and work in a host laboratory in Spain or Portugal ahead of the #FENSForum. 👉 buff.ly/grSyhzx @ibroorg.bsky.social @senc-neurociencia.bsky.social
Last Call! The individual-abstract deadline for the "Monitoring Molecules in Neuroscience" conference in Amsterdam (Sept 7-10, 2026) is tomorrow! Get the latest update on in-vivo neuro-methods from a brilliant lineup of keynote and symposia speakers: monitoringmolecules.org/speakers/. Please repost!
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If LLMs are increasingly used for data analysis, should we worry that they might encourage p-hacking? A recent preprint suggests that the answer may be yes, at least in relatively complex analytical pipelines. I share some personal experience here 👇 www.linkedin.com/posts/stefan...
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A huge effort and a new take on what constitutes the "feedforward pass" across the visual system. Make sure to check out our new preprint:
Excited about our new preprint: “The illusory simplicity of the feedforward pass: evidence for the dynamical nature of stimulus encoding along the primate ventral stream” arxiv.org/abs/2604.12825 Work with Sushrut Thorat, Anna Mitola, Paolo Papale, Peter König & Tim Kietzmann 🧵 thread below
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Burnout is a systemic problem, but individuals can take steps to cope with it and pave a path forward go.nature.com/4u38kku