Zach Nudelman

Zach Nudelman

@zednud.bsky.social

PhD Candidate | Cognitive Neuroscience | Vrije Universiteit Amsterdam | Eye <-> Brain Dynamics | ๐ŸŒ€๐ŸŽต

108 followers172 following9 posts

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Excited to share my first #preprint with @matthiasnau.bsky.social on how gaze behavior shapes brain activity during eyes-closed rest and sleep! Gaze-dependent activity was widespread even during sleep, including in many visual cortices, and altered brain-wide functional connectivity! ๐Ÿงต 1/8

biorxiv.orgBrain-wide gaze-dependent activity during eyes-closed rest and sleepGaze behavior and brain activity are tightly coupled during perception and mental imagery. Whether this coupling extends to eyes-closed states remains largely unknown, primarily because measuring eye ...

Zach Nudelman reposted

Thrilled to share our new #preprint, and super proud of @zednud.bsky.social and our work on eyeโ€“brain dynamics during eyes-closed rest and sleep! Also excited to share that Zach started his PhD with me recently! ๐ŸŽ‰ Lots of ideas and cool work ahead. Follow him on Bluesky and check out his thread! ๐Ÿงต

Zach Nudelman@zednud.bsky.social

Excited to share my first #preprint with @matthiasnau.bsky.social on how gaze behavior shapes brain activity during eyes-closed rest and sleep! Gaze-dependent activity was widespread even during sleep, including in many visual cortices, and altered brain-wide functional connectivity! ๐Ÿงต 1/8

Excited to share my first #preprint with @matthiasnau.bsky.social on how gaze behavior shapes brain activity during eyes-closed rest and sleep! Gaze-dependent activity was widespread even during sleep, including in many visual cortices, and altered brain-wide functional connectivity! ๐Ÿงต 1/8

biorxiv.orgBrain-wide gaze-dependent activity during eyes-closed rest and sleepGaze behavior and brain activity are tightly coupled during perception and mental imagery. Whether this coupling extends to eyes-closed states remains largely unknown, primarily because measuring eye ...
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Weโ€™re super excited about these findings because they suggest that eye-brain dynamics, as studied here, may provide a window into eyes-closed cognition. Think dreaming, anesthesia, coma โ€“ there are many cognitive states that lack a continuous behavioral read-out! 7/8

Our new MR-based eye-tracking approach may enable examining these effects across many cognitive states, which is what we will be doing next! Stay tuned! 8/8

Excited to share my first #preprint with @matthiasnau.bsky.social on how gaze behavior shapes brain activity during eyes-closed rest and sleep! Gaze-dependent activity was widespread even during sleep, including in many visual cortices, and altered brain-wide functional connectivity! ๐Ÿงต 1/8

biorxiv.orgBrain-wide gaze-dependent activity during eyes-closed rest and sleepGaze behavior and brain activity are tightly coupled during perception and mental imagery. Whether this coupling extends to eyes-closed states remains largely unknown, primarily because measuring eye ...
View full thread

These eye-brain dynamics largely persisted across wakefulness and sleep (but we also report evidence for local differences โ€“ promising targets for future work on differences across sleep stages etc.) 5/8

Finally, we found that partialing out the effect of gaze behavior from voxel time courses systematically altered functional connectivity estimates throughout the brain, a widely used measure of large-scale brain organization. 6/8

Excited to share my first #preprint with @matthiasnau.bsky.social on how gaze behavior shapes brain activity during eyes-closed rest and sleep! Gaze-dependent activity was widespread even during sleep, including in many visual cortices, and altered brain-wide functional connectivity! ๐Ÿงต 1/8

biorxiv.orgBrain-wide gaze-dependent activity during eyes-closed rest and sleepGaze behavior and brain activity are tightly coupled during perception and mental imagery. Whether this coupling extends to eyes-closed states remains largely unknown, primarily because measuring eye ...
View full thread

Here, we developed an unsupervised MR-based eye tracking method (MReyeMove, to be released) that infers gaze behavior directly from the MR signal of the eyes. It enabled us to examine gaze-dependent brain activity in a fantastic resting-state and sleep dataset shared by Gu and colleagues. 3/8

We found that activity covaried with inferred gaze behavior throughout the brain, spanning the cerebral cortex and cerebellum, and involving many regions associated with vision. The eyes were closed and people were sleeping! 4/8

Excited to share my first #preprint with @matthiasnau.bsky.social on how gaze behavior shapes brain activity during eyes-closed rest and sleep! Gaze-dependent activity was widespread even during sleep, including in many visual cortices, and altered brain-wide functional connectivity! ๐Ÿงต 1/8

biorxiv.orgBrain-wide gaze-dependent activity during eyes-closed rest and sleepGaze behavior and brain activity are tightly coupled during perception and mental imagery. Whether this coupling extends to eyes-closed states remains largely unknown, primarily because measuring eye ...

Eye movements and brain activity are known to be tightly coupled during perception and mental imagery. ๐๐ฎ๐ญ ๐๐จ ๐ฌ๐ฎ๐œ๐ก ๐ž๐ฒ๐žโ€“๐›๐ซ๐š๐ข๐ง ๐๐ฒ๐ง๐š๐ฆ๐ข๐œ๐ฌ ๐ž๐ฑ๐ญ๐ž๐ง๐ ๐ญ๐จ ๐ž๐ฒ๐ž๐ฌ-๐œ๐ฅ๐จ๐ฌ๐ž๐ ๐ฌ๐ญ๐š๐ญ๐ž๐ฌ ๐จ๐Ÿ ๐œ๐จ๐ ๐ง๐ข๐ญ๐ข๐จ๐ง ๐ฌ๐ฎ๐œ๐ก ๐š๐ฌ ๐ฌ๐ฅ๐ž๐ž๐ฉ? 2/8

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