Post
2026 lit review: SRMA: all the usual things except bicarb seem to help in hyperK no, prenatal APAP is not linked to autism @thesgem.bsky.social at #acep26
2026 lit review: no, prenatal APAP is not linked to autism — the big study that includes a sibling analysis make the potential association go away @thesgem.bsky.social at #acep26
2026 lit review: SRMA of 4 RCTs: no improved functional outcomes for tpa/TNK in minor strokes, 5x higher risk of symptomatic ICH (still low but risk >> 0 benefit @thesgem.bsky.social at #acep26
violent words, threats, and actions against ER health acre workers are both common and underreported lots of intoxication this study was among agitated patients so the numbers aren’t representative bit having observers record violence = shows underreporting @thesgem.bsky.social at #acep26
comprehensive review of c-collars in trauma- surprise!- no definitive evidence of benefit, + evidence of harm @thesgem.bsky.social at #ACEP26
900k ED visits/y for asymptomatic elevated BP 0.7% adverse outcomes after DC which is not long term hypertension – may be reasonable to start BP meds this obs study showed 1 mo supply assoc w slightly better 30d CV outcomes @thesgem.bsky.social at #acep26
more RCT (preprint) data showing tamiflu doesn’t help for sicker (eg oxygen, pressors, intubated) hospitalized patients (0, 5 or 10d) with flu @thesgem.bsky.social at #ACEP26
(I think for that back of the envelope NNH calculation you should subtract the placebo 13.7% from the 19.8%, so 1/6.1% =16.393) @thesgem.bsky.social at #ACEP26
another small RCT showing IM ketorolac is no more effective than oral ibuprofen @thesgem.bsky.social at #ACEP26
some limitations but overall this SRMA shows peripheral pressors are probably pretty safe @jamanetworkopen.com jamanetwork.com/journals/jam... @thesgem.bsky.social at #ACEP26
higher LOS, resource use by NPs may outweigh the (salary) cost savings, lots of limitations and intra-group variation @thesgem.bsky.social at #ACEP26