Niladri Sinha

Niladri Sinha

@2primehydroxyl.bsky.social

Assistant Professor @ University of Utah | interested in ribosomes and translational control in health and disease https://sinha.biochem.utah.edu

310 followers360 following21 posts

Pinned

I am delighted to share that I have started my lab in the Dept. of Biochemistry @uofubiochem.bsky.social at the University of Utah @utah.edu. My laboratory will study key aspects of protein synthesis and translational control in healthy and diseased states. #RNAsky sinha.biochem.utah.edu

sinha.biochem.utah.eduThe Sinha LabThe Sinha lab studies key aspects of protein synthesis and translational control in healthy and diseased states. We study the multifaceted roles of ribosomes as critical sensors of cellular stress.

Niladri Sinha reposted

We are excited to welcome our 2026 Postdoctoral Rising Stars to the U this Thur & Fri! Join us for an exciting series of short talks starting at 9am on Thursday in EHSEB Alumni Hall. And don't miss the McCloskey Lecture at 4pm by Dr. Andrei Korostelev (UMass)!

Niladri Sinha reposted

Congratulations to Dr. Brenda Bass our 2026 Rosenblatt Prize for Excellence recipient. Dr. Bass has transformed our understanding of the relationship between RNA biochemistry and human disease, and has also consistently excelled in training and service. attheu.utah.edu/facultystaff...

attheu.utah.eduBiochemist Brenda Bass wins Rosenblatt Prize - @theUDistinguished professor helped reveal the inner workings of RNA, the molecule that carries genetic instruction for building proteins.

Niladri Sinha reposted

So, so, honored by this award—it is daunting to know that my heroes have won this award! Thanks to my heroes and mentors, and my trainees, who are everything!!!!

U of Utah Dept of Biochemistry@uofubiochem.bsky.social

A huge congratulations to Brenda Bass @bbass.bsky.social for her Lifetime Achievement Award from the RNA Society @rnasociety.bsky.social! She is being recognized for her "groundbreaking discovery of A-to-I editing and outstanding contributions to this field."

Niladri Sinha reposted

Colliding ribosomes are potent signals of cellular stress. But do cells use ‘programmed’ ribosome collisions to regulate gene expression? I’m excited to present a new story from my lab led by Frederick Rehfeld(@fred-rehfeld.bsky.social) which revealed that the answer is YES! Read on to find out how👇

biorxiv.orgOxidative stress sensing by the translation elongation machinery promotes production of detoxifying selenoproteinsSelenocysteine, incorporated into polypeptides at recoded termination codons, plays an essential role in redox biology. Using GPX1 and GPX4, selenoenzymes that mitigate oxidative stress, as reporters,...

This is a unique opportunity to lead exciting projects and play an active role in shaping the lab culture, with a chance to apply a multidisciplinary toolkit (biochemistry, proteomics, genetics, and structural biology) to address exciting questions in translational control.

If you are a motivated and curious scientist eager to drive independent projects within a collaborative environment, please do not hesitate to reach out at niladri.sinha@biochem.utah.edu. Kindly re-post this opportunity amongst your professional networks.

It is an honor to return to the institution where I began my scientific journey. As I embark on establishing my lab, I approach this opportunity with excitement and humility. My goal is to train the next generation of scientists, paying forward the mentorship and support that shaped my career.

I am delighted to share that I have started my lab in the Dept. of Biochemistry @uofubiochem.bsky.social at the University of Utah @utah.edu. My laboratory will study key aspects of protein synthesis and translational control in healthy and diseased states. #RNAsky sinha.biochem.utah.edu

sinha.biochem.utah.eduThe Sinha LabThe Sinha lab studies key aspects of protein synthesis and translational control in healthy and diseased states. We study the multifaceted roles of ribosomes as critical sensors of cellular stress.

The lab will employ multidisciplinary approaches to study cellular responses to translation #stress and #proteotoxicity. We seek to identify quality control and signaling pathways triggered by ribotoxic stress and develop therapeutic strategies to target these pathways in #cancer and #aging cells.

Niladri Sinha reposted

We are happy to share that our snR30 story is finally out in @natureportfolio.nature.com 🥳 We report the first structure of a H/ACA snoRNP acting in ribosome synthesis thereby providing a detailed structural and biochemical view of the snR30 snoRNP guiding local 18S rRNA subdomain folding. 👇👇👇

Niladri Sinha reposted

Niladri Sinha reposted

You are up to date.