Ci Ji (CJ) Lim

Our paper in Science is out! @souravagrawal.bsky.social, @rlynn.bsky.social, @susvirkar.bsky.social, and the rest of the team show human RPA is a telomerase processivity factor essential for telomere maintenance. This reshapes our thinking about telomerase regulation. www.science.org/doi/10.1126/...

I'm hiring a postdoc for our NSF IntBIO project on songbird behavior, physiology and fitness! Start date as early as April 1 or as late as Sept 2027. Emphasis on behavioral endocrinology and transcriptomics, plus field ornithology based on applicant interests: academicjobsonline.org/ajo/jobs/33216.

a short history of me, in crayon. 400 million years of insects, a rocket in 1947, a white-eyed fly in a milk bottle, and now every one of my neurons, mapped and running in a jar. #SciArt #SciComm #drosophila

fascinating work on how the unit of 3D structure in our genomes (TADs) have evolved

We are #hiring for a professor at any level in the field of solid state nuclear magnetic resonance! Apply online by October 30: jobs.wisc.edu/jobs/assista...

New preprint by Kai Ling et al.! Distance-AF Multimer uses user-defined residue-pair distance constraints to guide AlphaFold-Multimer predictions, without retraining. From dimers, peptides, to larger assemblies, it helps improve protein complex models. www.biorxiv.org/content/10.6...

My major postdoctoral work is out today in Nature Biotechnology! Grateful to my co-authors Salvi and Corey, and to my advisor @stevenbanik.bsky.social

💡 NovoTags: new fluorophore-binding proteins from Julia Mahamid at EMBL, Luke Lavis, Linna An, David Baker, and colleagues. These small fusion tags bind Janelia Fluor dyes from Janelia Research Campus for super-resolution and multiplexed imaging: https://twp.ai/4hvy8t

Lead the next discovery at the LMB. We’re recruiting Group Leaders to join our Structural Studies and @cellbiol-mrclmb.bsky.social Divisions. Benefit from long-term support, access to outstanding core-facilities and a collaborative environment where science thrives. ➡️ mrclmb.ac.uk/research-lea...

New Preprint from Sunbul Group! RhoBAST-FLIM, a platform that resolves free from RNA-bound dyes, enables high-fidelity, lifetime-assisted super-resolution RNA imaging. Many thanks to Berkan for the wonderful collaboration and all the support from @murat-sunbul.bsky.social! doi.org/10.64898/202...

Programmable design of functional proteins from natural language www.nature.com/articles/s41... rdcu.be/3N9UHR1SEUSa

Calling all rising undergrad juniors & seniors: 9 weeks, mentorship from top scientists, up to $15K stipend to support "the most incredible" summer research experience. Want to learn more? Register for our live, #CechFellows webinar 10/26, 4pm ET! ➡️ bit.ly/4zKhIM8 | Program page: bit.ly/4dRWYJZ 🧪

My department at UCSF (Cell & Tissue Biology) is recruiting for a tenure-track Assistant/Associate Professor studying the fundamental cell biology underlying disease. Join us! App due Dec 1. aprecruit.ucsf.edu/JPF06272

Join us on Oct. 26 for Biochemistry Colloquium with Luke Gilbert. The Gilbert Lab uses CRISPR technologies to edit the epigenome and transcriptome of cancer cells, modelling how oncogene & non-oncogene addiction & tumor heterogeneity dictate cancer drug response: biochem.wisc.edu/2026/10/19/r...

Our Dept. of Genetics and Developmental Biology at the Institut Curie in the heart of Paris is hiring a new junior PI. It has a nice start up package and excellent I. Curie facilities. Please spread the word: Deadline Dec. 18th! jpi-recruitment-curie-umr3215-u934.curie.fr

Hey everyone- Lorne Protein 2027 abstract submission deadline is rapidly approaching! It’s always an exciting meeting… get your abstracts in before the door closes and I hope to see you there. #structuralbiology

This is one of the best emails I’ve ever received in my career. ❤️

"Because manuscripts reflected real progress towards our field’s goals, our assessment systems began relying on them as primary metrics...which is obviously flawed...Generative AI has broken this already-flawed proxy completely" journals.plos.org/plosbiology/...

How can histone acetyl-transferase acetylate a specific histone tail residue ? Using cryo-EM, we captured the MSL complex in a stable post-catalytic state, visualising the acetyl group on H4K16, a central mark for gene regulation authors.elsevier.com/sd/article/S...

We are looking for a postdoc. Candidates should have a PhD, at least one first-author paper, hands-on cryo-EM experience, and strong protein biochemistry skills. Please send your CV, research statement, and contact information for three references.

Just read this paper about cooperative binding of the DBD of FLI1 to GGAA-repeat DNA. It includes crystal structures with 2x, 3x, & 4xGGAA + EMSAs & fluorescence polarisation, showing that, on repetitive DNA, each FLI1 copy contacts the next & next+1, giving rise to cooperativity &increased affinity

The deadline is approaching! NIH is proposing changes to how peer review is used in funding decisions and how outcomes are reported and they want to hear from you. Comments are due by October 13! Comment here: grants.nih.gov/grants/guide...

Most animal species pack sperm DNA with protamines instead of histones. Protamines are essential for male fertility. They are among the fastest-evolving genes in animals. That makes little sense. We think we know why, in a new paper led by @ching-hochang.bsky.social. www.science.org/doi/10.1126/...

Come be my colleague at UCSF! Our department BTS (like the K-pop band, but aka Bioengineering and Therapeutic Sciences) is searching for TWO new faculty members. Links, timeline, and why two searches in this thread 🧵

Article: RAPseq enables large-scale identification of RBP–RNA interactions and reveals essentials of post-transcriptional gene regulation #research supported by Knut and Alice Wallenberg Foundation @claudiakutter.bsky.social #science #genetics tinyurl.com/ymrd8zxr

Johns Hopkins Biology is hiring a tenure-track Assistant Professor in computational genetics and genomics. Applications due Nov. 8th: apply.interfolio.com/194924 In my experience, this has been an incredibly supportive environment to build a lab. Please feel free to reach out with any questions.

Our latest development is now on bioRxiv: cryoSHIELDs — amphipathic peptide additives that make cryo-EM grid prep far more reliable. Tested across 24 protein systems, they enabled the first ABCC6 structure and GPCR–G protein structures at just 0.1–0.5 mg/mL! www.biorxiv.org/content/10.6...

We are updating our Expansion Microscopy (U-ExM) website with : - Protocols tips to help you get started - Examples of applications across different biological systems. - work in progress - an antibody database 👉 mocel.unige.ch/research-gro...

If you missed Jody Mou's terrific seminar back in March where she presented a bunch of unpublished data from her work in @nickpolizzi.bsky.social's lab, you can finally get all caught up 👇 youtu.be/SdkBhhBWZWk and pre-print: doi.org/10.64898/202...

Ribosome remodeling drives translation adaptation during viral infection and cellular stress: Molecular Cell www.cell.com/molecular-ce...

My latest, on OpenAI's dump www.nature.com/articles/d41...

Pls share:The Department of Microbiology at the University of Georgia invites applications for a tenure track Associate or Full professor position in Medical Mycology, beginning August 1, 2027. www.ugajobsearch.com/postings/508...

The Nitrogenase Supercomplex story is formally published! Looking forward to diving deep into its regulation over the next few years. rdcu.be/E7dGJPeDN3Ya

Yes, she knew it was a helix and even concluded there were 10 bp/turn, with bases separated by 34 Å. For an explanation of how you can deduce all that (and more) from these patterns, see youtu.be/2tMuMRY1oDo?...

📣Our department is hiring a new group leader!📣 Want to start your team in a vibrant scientific environment in the center of Paris? I was very lucky to do that 10 years ago, reach out if you have any question. Apply by December 18th: jpi-recruitment-curie-umr3215-u934.curie.fr

I'm super proud of this paper that just came out in G3--all of the authors (except for me and Dennis, my collaborator at the USDA-ARS at Madison) are/were undergrads in the lab! academic.oup.com/g3journal/ad...

Congratulations to Francis Halzen, UW–Madison professor of physics and principal investigator of @icecubeneutrino.bsky.social, on being named the 2026 Nobel Laureate in physics. His work helped unlock new ways of understanding the universe and the particles known as neutrinos. @nobelprize.org

Architect of polar neutrino detector wins physics Nobel | Science | AAAS 🔭🧪 @science.org www.science.org/content/arti...

Reminder🎗️: MCB is hiring Assistant Professors across 3 divisions! 🗓️ Application Deadline: October 19, 2026

Talk about a bright idea! 💡 Congrats to Karl Deisseroth, Peter Hegemann, and Georg Nagel on the #NobelPrize in Physiology or Medicine for foundational discoveries in optogenetics. All three openly share their remarkable tools through Addgene. Explore the tools:

BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”

“For four decades, the United States has run one of the most profitable trades in the world economy… import young people that the global labor market has underpriced—graduate students whose ability outruns their résumés—give them a place to prove themselves, and keep much of the upside”

Conformational diversity of collided ribosomes determines stress signaling pubmed.ncbi.nlm.nih.gov/42818177/ #cryoEM

Cryo-tides: synthetic peptides for cryo-EM grid preparation of multi-subunit protein complexes sensitive to the air-water interface www.biorxiv.org/content/10.64898/2026.09.30.755610v1 #cryoEM

In this preprint we describe new ASOs targeting telomerase RNA hTR. These ASOs are potent inhibitors of telomerase in vitro and induce telomere shortening with reduced proliferation in cancer cells. A new tool for telomere biology studies and a promising chemistry for cancer therapies. Check it out!

New online: A phosphoproteome atlas of human cell lines reveals the landscape of kinase activity

🚨 Please share! 🚨 I'm recruiting a fully funded 4-year Gatsby Sainsbury PhD studentship at Durham! 🌱🤖 Designing plant immune receptors from scratch, combining AI protein design with structural biology and plant immunity. If you're interested please get in touch! benthamlab.org shorturl.at/U2PdV

NIH is considering changes to how grant review results are reported, including eliminating numerical overall impact scores. Comments are due Oct. 13. Learn more and make your voice heard: https://www.ascb.org/science-policy/nih-proposes-changes-to-grant-review-tell-nih-what-you-think/

This month, the Department of Biochemistry welcomed Rae Brown to the team of instructional faculty, whose primary role is developing and teaching undergraduate biochemistry courses. Get to know more about Rae through their Q&A! biochem.wisc.edu/2026/09/23/n...

Yet another opportunity @dunnschool.bsky.social! We are looking for an Associate Professor If you have exciting research plans, @dunnschool.bsky.social is a great place: excellent science (and lovely people, obvs) www.path.ox.ac.uk/vacancy/asso...

✨🔬 Want to see our JF635b-conjugated #nanobodies in action? 📄 Check out the recent NanoLetters paper by Samrat Basak @samratb.bsky.social, Roman Tsukanov @romantsukanov.bsky.social, Felipe Opazo @opazo.bsky.social et al., doi.org/10.1021/acs....