Claudia Clopath Lab

Claudia Clopath Lab

@clopathlab.bsky.social

Professor in Computational Neuroscience at Imperial College London

2.5K followers168 following16 posts

Claudia Clopath Lab reposted

Jesse Geerts
@jessegeerts.bsky.social

Update on this work! We've extended our transitive inference study to large language models 🧵

Jesse Geerts@jessegeerts.bsky.social

🧠 How do transformers learn relational reasoning? We trained small transformers on transitive inference (if A>B and B>C, then A>C) and discovered striking differences between learning paradigms. Our latest work reveals when and why AI systems generalize beyond training data 🤖

Claudia Clopath Lab reposted

Masahiro Nakano
@masahironakano.bsky.social

I’m excited to share my first PhD preprint!🎉 We studied how interactions between medial entorhinal cortex (MEC) and hippocampus shape theta sequences during navigation, and asked whether some “planning-like” patterns in hippocampus could arise from upstream MEC dynamics. (1/8)

Claudia Clopath Lab
@clopathlab.bsky.social

Check out our new work on motor learning across multiple brain regions!

Jesse Geerts@jessegeerts.bsky.social

🧠 New year, new preprint! Why does motor learning involve multiple brain regions? We propose that the cortico-cerebellar system learns a "map" of actions where similar movements are nearby, while basal ganglia do RL in this simplified space. www.biorxiv.org/content/10.6...

Claudia Clopath Lab reposted

Jérôme Lecoq
@jeromelecoq.bsky.social


We're launching the data collection phase of the Community Predictive Processing project now that our plans have been published on arXiv 👉 arxiv.org/abs/2504.09614

arxiv.orgNeural mechanisms of predictive processing: a collaborative community experiment through the OpenScope programThis review synthesizes advances in predictive processing within the sensory cortex. Predictive processing theorizes that the brain continuously predicts sensory inputs, refining neuronal responses…
Claudia Clopath Lab
@clopathlab.bsky.social

How should you combine sensory inputs with your internal predictions? Well, use uncertainty directly computed by your prediction-error circuits. Cool? Check out our Nat. Com. paper with Loreen Hertäg and @k47h4.bsky.social . www.nature.com/articles/s41...

nature.comUncertainty estimation with prediction-error circuits - Nature CommunicationsHow the brain integrates sensory input and predictions to adapt to change is not fully understood. Here authors build a neural network model to show how prediction-error neurons compute uncertainty of...
Claudia Clopath Lab
@clopathlab.bsky.social

Check out our new method to optimize neural representations from behaviour!

Sainsbury Wellcome Centre@sainsburywellcome.bsky.social

“SIMPL: Scalable and hassle-free optimisation of neural representations from behaviour” openreview.net/forum?id=9kF... From @tomnotgeorge.bsky.social Pierre Glaser, Kim Stachenfeld, @caswell.bsky.social @clopathlab.bsky.social

openreview.netSIMPL: Scalable and hassle-free optimisation of neural...Neural activity in the brain is known to encode low-dimensional, time-evolving, behaviour-related variables. A long-standing goal of neural data analysis has been to identify these variables and...
Claudia Clopath Lab
@clopathlab.bsky.social

Want to hear more about how feedback can guide learning in RNNs for motor adaptation. Here is our new paper in Nat. Com. with Barbara Feulner and @juangallego.bsky.social www.nature.com/articles/s41...

nature.comA neural implementation model of feedback-based motor learning - Nature CommunicationsHow the brain adapts our movements to new conditions remains unclear. Here, the authors show that a recurrent neural network that controls its output using error-based feedback can learn to count...
Claudia Clopath Lab
@clopathlab.bsky.social

Check out our new paper with the Margrie lab in Cell on motor and vestibular signals in the visual cortex. Well done Mateo Velez-Fort!

Sainsbury Wellcome Centre@sainsburywellcome.bsky.social

Check out the full paper in @cp-cell.bsky.social from Mateo Velez-Fort, Lee Cossell, Laura Porta, @clopathlab.bsky.social and Troy Margrie www.cell.com/cell/fulltex...

cell.comMotor and vestibular signals in the visual cortex permit the separation of self versus externally generated visual motionMouse primary visual cortical neurons receive running, linear translation, and visual inputs that linearly combine to differentially represent the same visual flow information, depending on the motion...

Claudia Clopath Lab reposted

Sainsbury Wellcome Centre
@sainsburywellcome.bsky.social

Replying to @sainsburywellcome.bsky.social

Read the full paper in @science.org from Sara Mederos, Patty Blakely, @nicolevissers1.bsky.social @clopathlab.bsky.social and @sonjahofer.bsky.social ⬇️ www.science.org/doi/10.1126/...

science.orgOverwriting an instinct: Visual cortex instructs learning to suppress fear responsesFast instinctive responses to environmental stimuli can be crucial for survival but are not always optimal. Animals can adapt their behavior and suppress instinctive reactions, but the neural pathways...
Claudia Clopath Lab
@clopathlab.bsky.social

See our new paper in Science with the Hofer lab. Well done Sara Mederos!

Sonja Hofer@sonjahofer.bsky.social

So excited to see this out, heroic effort by the brilliant Sara Mederos, uncovering the detailed brain mechanisms of how animals learn to overcome their instinctive fear responses, from neural circuits & cell types down to synaptic plasticity mechanism! www.science.org/doi/10.1126/...

science.orgOverwriting an instinct: Visual cortex instructs learning to suppress fear responsesFast instinctive responses to environmental stimuli can be crucial for survival but are not always optimal. Animals can adapt their behavior and suppress instinctive reactions, but the neural pathways...

Claudia Clopath Lab reposted

Sonja Hofer
@sonjahofer.bsky.social

So excited to see this out, heroic effort by the brilliant Sara Mederos, uncovering the detailed brain mechanisms of how animals learn to overcome their instinctive fear responses, from neural circuits & cell types down to synaptic plasticity mechanism! www.science.org/doi/10.1126/...

science.orgOverwriting an instinct: Visual cortex instructs learning to suppress fear responsesFast instinctive responses to environmental stimuli can be crucial for survival but are not always optimal. Animals can adapt their behavior and suppress instinctive reactions, but the neural pathways...

Claudia Clopath Lab reposted

Tom George
@tomnotgeorge.bsky.social

What are the brain’s “real” tuning curves? Our new preprint "SIMPL: Scalable and hassle-free optimisation of neural representations from behaviour” argues that existing techniques for latent variable discovery are lacking. We suggest a much simpl-er way to do things. 1/21🧵

Claudia Clopath Lab reposted

Blake Richards
@tyrellturing.bsky.social

This paper from Claudia Clopath's lab is very exciting for me. I've been musing for a while now that the challenge of approximating gradient descent is probably made way easier in the brain by feedback signals for control. Here they show it!!! openreview.net/forum?id=xav... 🧠📈 #NeuroAI 🧪

openreview.netFeedback control guides credit assignment in recurrent neural networksHow do brain circuits learn to generate behaviour? While significant strides have been made in understanding learning in artificial neural networks, applying this knowledge to biological networks...

You are up to date.