Dalila

Dalila

@dalilatm.bsky.social

Interested in research ethics and all about #lupus #lupusnephritis | Running support group #Wales 🏴󠁧󠁢󠁷󠁬󠁳󠁿| We need a cure for Lupus 🦋 #MyViews

283 followers388 following252 posts

Dalila reposted

UK Kidney Association
@ukkidney.org

🌍 Lupus nephritis in Kenya: real cases, shared learning Join our International Committee & Kenya Renal Association for this free webinar. 🎤 Dr Gilford M Mwokamba 📅 18 Nov | 🕓 16:00 GMT Explore real-world cases & share clinical learning across international settings. 🔗 https://ow.ly/InlH51001Yw

Dalila reposted

Chris Wincup
@chriswincup.bsky.social

🦴 Lupus arthritis isn’t simply RA in #SLE Our new review synthesises evidence for distinct synovial immunology, highlights major gaps in tissue research, and calls for single-cell studies and better imaging-based outcomes to advance precision treatment doi.org/10.3389/fimm...

Dalila
@dalilatm.bsky.social

💡Inspiring interview that shows key priorities for moving forward: meaningful patient involvement, innovative treatments, interdisciplinary collaboration/multidisciplinary perspectives & international partnerships. Thank you for sharing @kingscollegelondon.bsky.social www.kcl.ac.uk/healthy-life...

kcl.ac.ukHealthy Lifespan for All: Professor Sheila SinghIn this first of our new Healthy Lifespan for All: Researcher Spotlight Series, we are highlighting Professor Sheila Singh, Richard Dimbleby Professor of Cancer Research and Head of the…

Dalila reposted

George Robinson
@georgearobinson.bsky.social

The Robinson Lab website is live in #LupusAwarenessMonth! robinsonlab.co.uk We study the immunology and metabolism of childhood-onset lupus at UCL. Pages for families, and an @immuninjas.bsky.social game. Thanks @arthritisuk.bsky.social, @lupusuk.bsky.social, @royalfreecharity.org, and collaborators

robinsonlab.co.ukRobinson Lab | UCLThe Robinson Lab at UCL studies childhood-onset lupus: interferon, immune phenotyping, heart and blood vessel risk, and sex differences in autoimmunity.

Dalila reposted

Nobel Prize
@nobelprize.org

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2026 #NobelPrize in Chemistry to Henri B. Kagan and Kenso Soai “for the discovery of non-linear effects and autocatalysis in asymmetric organic synthesis.”

Dalila reposted

ACR Journals
@acr-journals.bsky.social

In a Swedish national cohort with newly diagnosed SLE 2006-2022, the role of oral GC exposure in organ damage differed across organ domains. For several domains, especially cardiovascular damage, GC exposure over a 3-year period was required to fully capture the association with organ damage risk

doi.orgOral glucocorticoid dose patterns and organ damage in systemic lupus erythematosus – a nationwide cohort studyBackground Evaluating the relationship between glucocorticoid (GC) exposure and organ damage in systemic lupus erythematosus (SLE) is challenging since GC dose varies over time. It is unclear which ...

Dalila reposted

ifaiarthritis.bsky.social
@ifaiarthritis.bsky.social

October is full of opportunities to raise awareness & amplify patient voices. From arthritis and psoriasis to mental health, invisible disabilities, employment & occupational therapy - these experiences are all connected to life with AiArthritis diseases. #AiArthritis #Awareness

Dalila reposted

University of Oxford
@ox.ac.uk

Researchers are developing more precise ways to target the neural circuits involved in learning, with potential applications across sport, music, surgery and rehabilitation. As the technology advances, discover what the science tells us about its potential ⬇️ https://bit.ly/4yjkXtT

Dalila reposted

Dr. John Cush
@rheumnow.bsky.social

Cluster analysis of Spanish RELES #SLE SLE cohort reveals 3 groups. C1 (n 168) was younger, w/ lupus nephritis, low C3, intensive Rx, high infx & damage. C2 (175) w/ cytopenias, serositis, APL & dsDNA(+). C3 (452) mild skin-Jts, less serologic activity & complications buff.ly/Oj3vuij

Dalila reposted

ACR Journals
@acr-journals.bsky.social

Cross-sectional study of 451 adults w/ SLE found that 80% used a dietary supplement, and more than half used multiple supplements Almost 1/3 had a potential supplement–medication interaction, highlighting a potential underrecognized patient safety concern in lupus care AC&R doi.org/10.1002/acr....

Dalila reposted

kahlenberglab.bsky.social
@kahlenberglab.bsky.social

A paper 4 years n the making is finally out! A single cell map of lupus photosensitive responses. Thanks to our team, our patients, and @lupusresearch.bsky.social for funding this! urldefense.com/v3/__https:/...

urldefense.comMyeloid infiltration and epidermal dysregulation characterize cutaneous photosensitivity in systemic lupus erythematosusIn photosensitive lupus, dysregulated cutaneous UV responses recruit and activate monocyte-derived dendritic cells that may drive lesion development.

Dalila reposted

UCL
@ucl.ac.uk

Today is #WorldAlzheimersDay. At UCL‬ we're tackling the global challenge of #dementia by focusing our world-leading expertise on prevention, care and cure. Explore our research stories to learn more: 🔗 https://bit.ly/3SwtZE7 #UCLDementia

Dalila reposted

European Academy of Neurology
@ean.org

Final chance to register for our migraine during pregnancy webinar! 🧠 Migraine During Pregnancy, Postpartum and Breastfeeding: Understanding the Hormonal Aspect and Implementing Safe Strategies for Acute and Preventive Treatment ⏰ 23.09.26 | 18:00-19:30 CEST 💻 on eanCampus 🔗 buff.ly/xBQ03rQ

Dalila reposted

The Guardian
@theguardian.com

Scientists create mice with part-human brains

theguardian.comScientists create mice with part-human brainsResearchers hope to shed light on conditions such as schizophrenia, epilepsy, cerebral palsy, intellectual disability and rare forms of dementia Researchers have created mice with half-human brains in an effort to understand and develop new treatments for disorders such as schizophrenia, epilepsy, cerebral palsy, intellectual disability and rare forms of dementia. The scientists transplanted lab-grown human brain cells into animals that were engineered to be born without a cortex or hippocampus. This made space for the human tissue to grow inside the rodents’ skulls. Continue reading...

Dalila reposted

Fabien VINCENT
@fabozy.bsky.social

Beyond conventional biomarkers: can blood metabolomics reveal new clues about #Lupus? Our #Frontiers in #Immunology study identified candidate metabolomic signatures associated with lupus nephritis, remission & glucocorticoid use in #SLE frontiersin.org/journals/imm... @monashuniversity.bsky.social

frontiersin.orgFrontiers | Untargeted serum metabolomics in systemic lupus erythematosus reveals candidate metabolomic signatures associated with clinical phenotypes and glucocorticoid useObjectives. Despite promising advances in metabolomics for biomarker discovery in systemic lupus erythematosus (SLE), studies examining associations with det...

Dalila reposted

Waggoner Lab
@labwaggoner.bsky.social

Delighted to publish this with my friends in @ajhgnews.bsky.social @cincychildrens.bsky.social IRF7 haplotype amplifies activity with immunological risks and benefits scienceblog.cincinnatichildrens.org/when-antivir... doi.org/10.1016/j.aj... www.science.org/content/arti...

scienceblog.cincinnatichildrens.orgWhen Antiviral Defense and Autoimmunity Collide: New Insights into Lupus Genetics - Research HorizonsResearchers discovered how a common lupus risk variant may boost antiviral defenses while increasing autoimmunity risk.

Dalila reposted

The American Journal of Human Genetics
@ajhgnews.bsky.social

🧬New from Kottyan & co 📄A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-α, enhancing antiviral defense and exacerbating autoimmunity

cell.comA highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-α, enhancing antiviral defense and exacerbating autoimmunityVirolainen et al. combine human genetics, functional genomics, and mouse models to show that a common lupus-risk IRF7 haplotype enhances IRF7 nuclear localization, DNA binding, and type I interferon production. The haplotype improves antiviral defense but increases autoreactivity, revealing an evolutionary trade-off between host protection and autoimmunity.
Dalila
@dalilatm.bsky.social

🤩 Wonderful presentation today on autoimmunity & neural dysfunction in Complex Regional Pain Syndrome #CRPS. Lots of mentions of #lupus & how autoimmunity is expressed in CRPS. Data on brain changes seen in CRPS after years of living with persistent pain. 💡Many Qs in autoimmunity needing an answer

Dalila
@dalilatm.bsky.social

While we’re seeing extraordinary advances driven by AI, over the next years it’ll be important to remember the incredible capabilities of humans on their own. Here: Michelangelo’s Moses and Beethoven’s Ninth Symphony (Pics: Wikipedia)

Dalila reposted

Renal and Urology News
@renalurologynews.bsky.social

At 12 months, the complete response rate was 36.7% in the supportive care group and 49.6% in patients who received immunosuppressive therapy. https://www.renalandurologynews.com/news/rituximab-lupus-nephropathy-crr-steroid-exposure-treatment-risk/

renalandurologynews.comRituximab Improves CRR, Reduces Steroid Exposure in Lupus Membranous NephropathyA real-world study revealed little difference in 12-month renal response rates among immunosuppressive regimens for patients with first-onset PLMN.

Dalila reposted

Rheumatology Advisor
@rheumatologyadv.bsky.social

From @jrheumatol.bsky.social: Younger patients with systemic #lupus erythematosus face significantly greater capability and opportunity barriers to treatment adherence compared with older populations. https://www.rheumatologyadvisor.com/news/logistical-barriers-sle-treatment-nonadherence/

rheumatologyadvisor.comAdults Younger Than 30 Years With SLE Face More Barriers to Medication AdherenceMedication nonadherence in systemic lupus erythematosus is highest among younger adults facing access and scheduling barriers.
Dalila
@dalilatm.bsky.social

Watched ☑️ Beautifully structured, with the key concepts well defined and linked together in a topic that’s far from black & white 👍👏🏻 #lupus @lupusacademy.bsky.social

Chris Wincup@chriswincup.bsky.social

Brilliant few days at the Lupus Academy in Bratislava 🇸🇰 A real privilege to contribute, but even better to learn from so many outstanding colleagues across the lupus community 💡 Lots of great discussions and new ideas to take back to clinic and research 🧬

Dalila reposted

ACR Journals
@acr-journals.bsky.social

September A&R Clinical Connections (1 of 2): Multi-Omic Profiling Reveals Immune Cell Priming Signature in Lupus Key Points: • Proteins released from inflamed tissues could be detected in the blood of patients with lupus. continues

Dalila
@dalilatm.bsky.social

Interesting short talk on the neurological effects of #menopause, & perimenopause as a neurological transition phase involving changes in the brain. Sth I’ve often wondered about when listening to women with #lupus talk about their experiences of brain fog #TheFemHealthProject @springernature.com

Dalila
@dalilatm.bsky.social

🤔 Apart from sharing the name (lupus = wolf), which comes from the disease’s early presentation, I’m not a huge fan of delving into the biology & characteristics of wolves 🐺 & drawing comparisons when talking about #lupus as a disease 🙅‍♀️

Dalila
@dalilatm.bsky.social

Well done to all the parents for making it through the 6 weeks of summer holidays 👍 May you enjoy your first scream-free coffee in peace… also known as the first day back at school ☕

Dalila reposted

ACR Journals
@acr-journals.bsky.social

New US data from 5 CDC lupus registries show striking age differences in SLE incidence: rates peak at ages 30–39 in women, but 60–69 in men. Black women ages 20–39 had the highest incidence. Important insights into who develops lupus and when Arthritis & Rheumatology doi.org/10.1002/art....