David A Muller

David A Muller

@davidamuller.bsky.social

"Learning more and more about less and less" Materials Physics and Electron Microscopy at Cornell (he/him) https://muller.research.engineering.cornell.edu/

456 followers518 following142 posts

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#cryoEM Lena and I started working on this project almost 10 years ago, with @ktspoth and then Yue taking data. Lena passed away before she could finish the paper, even as other groups were finding it very useful. With Yue and friends we finally got something out! www.biorxiv.org/content/10.1...

biorxiv.orgDose-Efficient Cryo-Electron Microscopy for Thick Samples using Tilt-Corrected Scanning Transmission Electron Microscopy, Demonstrated on Cells and Single ParticlesbioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Cornell's cows are absolutely out standing in their fields right now (all 2,000+ acres). Maybe the NYT just forgot we are an ivy again?

The New York Times@nytimes.com

In @nytopinion.nytimes.com The problem on college campuses is not just that students lack civility, Michal Leibowitz writes, but that “our college education does almost nothing to develop the sense that what we do in our day-to-day lives resonates with people beyond ourselves.”

@sciencex.bsky.social ex.bsky.social picked up our #ptychography paper on imaging the atomic-scale roughness in transistor channels in 3D, in a single scan and without having to tilt the sample. ⚛️

ex.bsky.socialBluesky
Science X / Phys.org@sciencex.bsky.social

High-resolution 3D electron microscopy has enabled direct visualization of atomic-scale "mouse bite" defects in semiconductor transistors, offering new insights for chip characterization and development. doi.org/hbq6sc

David A Muller reposted

Bluesky is the new science Twitter, new study by @whysharksmatter.bsky.social and Julia Wester concludes! "Results show that for every reported professional benefit that scientists once gained from Twitter, scientists can now gain that benefit more effectively on Bluesky than on Twitter."

academic.oup.comScientists no Longer Find Twitter Professionally Useful, and have Switched to BlueskySynopsis. Social media has become widely used by the scientific community for a variety of professional uses, including networking and public outreach. For

#cryoEM Lena and I started working on this project almost 10 years ago, with @ktspoth and then Yue taking data. Lena passed away before she could finish the paper, even as other groups were finding it very useful. With Yue and friends we finally got something out! www.biorxiv.org/content/10.1...

biorxiv.orgDose-Efficient Cryo-Electron Microscopy for Thick Samples using Tilt-Corrected Scanning Transmission Electron Microscopy, Demonstrated on Cells and Single ParticlesbioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Imaging hydrogen atoms with ptychography

schuylerzixiaoshi.bsky.social@schuylerzixiaoshi.bsky.social

Hydrogen, the universe’s most abundant atom, is also the hardest to see in solids. Using electron ptychography, we directly reveals hydrogen’s hidden structures inside metals, as reported in our JACS paper (pubs.acs.org/doi/10.1021/...). @davidamuller.bsky.social @jacs.acspublications.org

Jim West's group taught us everything we know about building ultra-quiet rooms

Ainissa Ramirez, PhD@ainissaramirez.bsky.social

SPARK sighting at @possible-futures.bsky.social! Less than two weeks till it's available at a bookstore near you! Share the story of Jim West and his invention of the microphone we all use today on Zoom, phones 🎤 Preorder here: bit.ly/SPARKbk #WomeninSTEM 🧪 #SciArt #Booksky #Science #Blacksky

#cryoEM 🧪⚛️ Lena’s paper on imaging thick biological sections with STEM is finally published! We started this work almost 10 years ago. After Lena passed in 2023, I spent much of my sabbatical working with Yue and Steve to wrap this up. Also learned a lot about TEM vs STEM dose efficiency

We had 35 participants at our summer school a few weeks ago testing this on their laptops. Turns out a Macbook M4 pro is almost as fast as a 10GB slice of an A100. From the school, here is a 1-hour reconstruction. (Data took a few seconds to record at the school in a crowded scope room)

David A Muller reposted

One of my favorite things is seeing how publishers around the world reinterpret covers for foreign language editions of our books. The Alchemy of Us is being published in Korean. A side by side comparison -- same great content, totally different vibe.

Danielle was one of Lena’s students 🧪

cryoEM papers@cryoempapers.bsky.social

Revealing the Crystalline Architecture of Semicrystalline Ion Exchange Membranes for the Design of Conductive and Durable Alkaline Anion Exchange Membranes pubmed.ncbi.nlm.nih.gov/40415331/ #cryoEM

So the crazy thing here is the company this is supposed to be about is Corning. The company famous for its glass research. And the across the board metric is a measure of how similar individual atom positions are in their CRYSTAL structures. So much is nuts here, but that should have been a red flag

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This has been going for a while. When I worked at Lumon, erm Lucent Technologies in the late 90’s this similarity was also noted, but that is was also inflamed. Still an improvement on the previous deathstar logo

After reading this statement, it is worth remembering that the I in DEI is Inclusion. The opposite of Inclusion is separateness. The Afrikaans word for separateness is Apartheid

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"This is fine.gif" Let's just say I had an interesting time trying to find a cognizant program officer on Tuesday - every time someone inside NSF referred me to someone else, within 10 minutes, the new email bounced as that person was removed from the system www.politico.com/news/2025/02...

politico.com‘You screwed people’: Inside the National Science Foundation’s firing of 168 workersAt an emotional meeting, foundation officials announced layoffs for about 10 percent of their workforce and warned of more firings to come.

2 papers back to back in this issue from alums of Fraser Stoddart's group. Also a chainmail-like polymer from Will Dichtel that we imaged #chemsky 🧪 news.northwestern.edu/stories/2025...

news.northwestern.eduChainmail-like material could be the future of armorFirst 2D mechanically interlocked polymer exhibits exceptional flexibility and strength
Wenjie Zhou@wenjiez.bsky.social

[1/6] Excited to share our latest research featured on the @science.org cover! Meet PAMs (Polycatenated Architected Materials)—a new class of 3D-architected materials that challenge traditional boundaries between solids and granular matter. Read our paper: www.science.org/doi/10.1126/...

David A Muller reposted

Cannot stop thinking about how Octavia Butler wrote a book in 1993 about climate change. It opens with deadly fires in LA in 2025. In the story, a fascist President has just won office with the campaign slogan "Make America Great Again." She was a modern day Nostradamus. If only we'd listened.