David Robbe

David Robbe

@davidrobbe.bsky.social

Neuroscientist at Institut de Neurobiologie de la Méditerannée (Marseille). Basal ganglia, time, effort, foraging, vigor, motor control. Leaning toward philosophy (obsessed with Henri Bergson)

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David Robbe reposted

David Robbe reposted

With profound sadness we announce the passing of our colleague and friend Antoine de Chevigny, an expert in cortical development respected for his creativity and curiosity and cherished for his kindness and joie de vivre. He leaves an immense void. Support for his partner: tinyurl.com/2yrh7huc

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Zelda and Maud are 3rd and 4th year PhD students. Passionate, hardworking, and fun, they have developed skills in rodent behavior (freely moving foraging), data analysis, and perturbation experiments. They are looking for postdocs. Contact them if interested!

@maudschaffh.bsky.social presented work on how unilateral perturbation of dSPN/iSPN affects the behavior of mice engaged in a novel foraging task with a lateralized procedural component. The work is based on a cool patch foraging task we just published. www.cell.com/iscience/ful...

cell.comThe Tower Foraging Park: A paradigm for studying cognitive and motor processes underlying behavioral flexibility in freely moving miceBiological sciences; Behavioral neuroscience; Laboratory animal science

Zelda presented the work she has been doing in collaboration with Thomas Morvan on the complementary motivational functions of the dorsal and ventral striatum in rats performing an effort-based foraging task. You can check out the latest preprint here: www.biorxiv.org/content/10.1...

biorxiv.orgComplementary contributions of dorsal and ventral striatum to cost-benefit vigor adaptationsHumans and other animals adjust when and how fast they execute goal-directed actions according to expected costs and benefits. Yet, the behavioral principles and brain regions underlying adaptive vigo...

David Robbe reposted

Check this exciting new foraging paper. Very excited that we are currently collaborating with @davidrobbe.bsky.social group to model behavioral mechanisms underlying foraging startegies in the The Tower Foraging Park.

David Robbe@davidrobbe.bsky.social

Excited to share our new paper: "The Tower Foraging Park: A paradigm for studying cognitive and motor processes underlying behavioral flexibility in freely moving mice,". Out now in @cp-iscience.bsky.social 🧵1/9 www.cell.com/iscience/ful...

Finally, both groups faced a harder challenge: after leaving a tower, the next rewarded tower and direction were picked at random. Mice previously trained on daily reversals outperformed those trained on a fixed rule, suggesting the reversal training made them more adaptive when foraging is harder.

This paper also makes a broader argument: patch foraging in freely moving animals can provide an intermediate between trial-based tasks (with their pros and cons) and more naturalistic approaches that lack the experimental perturbations necessary to understand the logic of adaptive behavior.

After 6 days, the rewarded direction was reversed. Mice persisted briefly in the now unrewarded direction, then adapted. Strikingly, turn trajectory variability was immediately increased by unrewarded outcome while speed remained fast, revealing unexpected uncoupling of these 2 parameters

Protocol 2 (n=32 mice): rewarded direction switched every day. Each morning mice started by testing the previous day's direction before switching, and across days they got progressively faster at adapting, a form of meta-learning. Uncoupling of speed and trajectory variance adaptation

In the Tower Foraging Park (TFP), mice harvest water by making quarter-turns around towers. Each tower eventually depletes, so mice must decide when to leave and explore another, the classic explore/exploit dilemma. Here, we ran two main protocols, adding a procedural learning/flexibility twist

Protocol 1 (n=19 mice): only one turning direction rewarded, abrupt depletion, two 12-min sessions/day. Mice developed a strong directional preference within just a few sessions, and only rewarded turns got progressively faster and less variable in trajectory.

David Robbe reposted

David Robbe reposted

Peer review is important and useful but we should focus our efforts on a small number of papers that matter (making big claims, using new approaches) and let the vast majority of work live on a preprint server to be judged by their utility over time to domain experts.

Carl T. Bergstrom@carlbergstrom.com

Springer-Nature statement “Whilst the details of peer review are confidential, we can confirm that the article underwent two rounds of review from two independent peer reviewers, supporting an accept decision.” How am I now expected to believe that two people looked at the paper twice and DGAF?

David Robbe reposted

David Robbe reposted

Soapbox time: the problem with metabolic efficiency arguments in neuroscience is that they often confuse energy efficiency with energy expenditure. Biological systems are optimized for energy efficiency, but that does NOT imply they are optimized for low energy expenditure 🧵 1/

This review below by Herz and Brown, about effort, bradykinesia in Parkinson disease is really such an excellent read. If you are interested in dopamine, basal ganglia, motor control and motivation, this is really a must read 👌 doi.org/10.1093/brai...

doi.orgMoving, fast and slow: behavioural insights into bradykinesia in Parkinson’s diseaseHerz and Brown review observations of movement slowness in Parkinson’s disease and discuss these findings in a behavioural framework borrowing principles f

David Robbe reposted

Super pleased with this one, led by the amazing PhD student and foraging expert @emmavscholey.bsky.social!

Mark D Humphries@markdhumphries.bsky.social

🧪Preprint! How foragers depart from optimal models can tell us a lot about how they compute their decisions. A strong but underexplored departure is that foragers widely vary when they leave identical patches. A 🧵 doi.org/10.1101/2025... With @emmavscholey.bsky.social @brainapps.bsky.social

David Robbe reposted

The race to churn out papers is a systemic problem. Early career scholars are desperate to get more papers to compete in the academic job market. This can make it hard for faculty mentors hard to reduce their output unless they shrink their lab (which removes opportunities from next generation).

I haven’t posted much here since leaving Twitter/X, but I feel a growing need to share again papers and thoughts about science, the brain, and our too often absurd academic life . My feed hasn’t been very exciting so far, so let’s see if posting and interacting more helps

David Robbe reposted

New Pre-Print: www.biorxiv.org/cgi/content/... We’re all familiar with having to practice a new skill to get better at it, but what really happens during practice? The answer, I propose, is reinforcement learning - specifically policy-gradient reinforcement learning. Overview 🧵 below...

biorxiv.orgPolicy-Gradient Reinforcement Learning as a General Theory of Practice-Based Motor Skill LearningMastering any new skill requires extensive practice, but the computational principles underlying this learning are not clearly understood. Existing theories of motor learning can explain short-term ad...

David Robbe reposted

Can one bring together Reinforcement learning and Drift Diffusion models to understand collective foraging ? Congrads to Jonathan Marienhagen , Lisa Blum Moyse and Dominik Deffner on this new study. Very happy that I was part of this collaboration. Preprint here: osf.io/preprints/ps...

David Robbe reposted

It is simply amazing how Djokovic can so often anticipate where Alcaraz, one of the most creative players, will direct his next shot. Perception intertwined with action. This match is just incredible...

David Robbe reposted