Studying immune gene evolution is rarely about a lack of data, it’s about keeping data, biology, and interpretation aligned as everything changes.
New GLUE Genomics post: from viral genomes to immune genes, using interferon lambda as a case study.
gluetools.substack.com/p/glue-resou...
Excited to share our work on #AncientRNA from alcohol-preserved lungs, recovering the oldest human RNA virus genome (an 18th-century rhinovirus). Our study shows that viral RNA remnants persist in centuries-old tissue, opening new ways to study virus evolution and historical disease #Paleovirology🫁🦠
Now live! Nearly all human genes contain multiple transcript isoforms - and the genes that predominantly control infection, ISGs, are no different. Using PacBio with analysis help from Yan Guo, Himadri noticed a never-before-seen transcript isoform of ISG15 that potently restricts flu 1/4
Happy to see @joelrc.bsky.social's paper identifying cellular heterogeneity in basal OASL expression as a major determinant of interferon induction during influenza virus infection out in its final form:
www.pnas.org/doi/10.1073/...
Happy new year, hope everyone's 2026 is better than 2025!
SMBE2026 Symposium 13 | Perspectives on paleo-omics: defining functional evolution of ancient viruses in the era of big data
📨 Abstract submission
smbe2026.org/abstracts
📋 Programme details
smbe2026.org/programme#SMBE2026
Actively looking for a postdoc interested in host-virus evolution. Please apply to the #MahanFellowship This fellowship provides early career scientists with the opportunity to join a Fred Hutch CompBio lab (like ours!). If interested please contact me to coordinate proposal and apply by Dec 05 2025
We mourn the passing of Nobel laureate David Baltimore, a towering figure in molecular biology and virology, and a pioneer and founder of ASV. His discoveries transformed science and medicine, and his mentorship inspired generations. His legacy will continue to guide and inspire virology and ASV.
📢📢One more day to submit your abstract to the Ancient Pathogen Genomics Symposium 🧬🦠🦴📢📢
Great program and community 💚
🔗 Details: liigh.unam.mx/apg/
🇲🇽 ¡Nos vemos en Querétaro! 🌮🪅
Very Happy to share the very first paper of the Lab! Qing Yang & Ben Nilsson-Payant found that modulating Influenza NS1 levels reveals a ranking in its inhibitory roles: IFN < ISGs < UPR. Huge thanks to Ben tenOever for his helpful advice! For many more to come 🥂
bit.ly/NS1Priority
Hello #BlueSky friends! I work on #cancer #genomics in 🇲🇽, focused on acral #melanoma, #liver diseases and also on capacity building and training. We seek to generate genome sequences from cancer and pre-cancer from Latin America to study risk factors & contributors. Excited to join this community!
👩🔬New **PostDoc** Opportunity!👨🔬
My new Epidemiology & Virus Evolution (EVE) group at SwissTPH is looking for a PostDoc in evolution & phylogenetics of respiratory viruses 🦠🌳
Interested? See here for more details & to apply!
jobs.swisstph.ch/Vacancies/92...
Please share!😁
m7GpppNm - VERY EXCITED to share my postdoctoral work in @ramlabuw.bsky.social’s lab, now @bioRxiv. We find that cellular RNA interacts with MAVS, the adaptor protein of the RIG-I-like receptor pathway, to promote antiviral signaling. A 🧵:
We have an open virology faculty search at the University of Illinois! We have world class core facilities and a fantastic collaborative group of young faculty working on cutting edge questions in virus biology...you could be next!
Please re-post/RT/re-bleet/whatever it is called here!