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David Christensen from the Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social is joining #BOARD26 to promote understanding of how animal research and other approaches complement each other. #BOARD #EARA #SCICOMM
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David Christensen from the Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social is joining #BOARD26 to promote understanding of how animal research and other approaches complement each other. #BOARD #EARA #SCICOMM
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As the political climate around animal research becomes less supportive in the UK, it is our interest to argue for & protect organismal biology. BBSRC opened a survey, which gives us a timely platform. Please fill & share link among colleagues. Deadline: 9/2 engagementhub.ukri.org/mrc-bbsrc/la...
An elegant approach using a mix of technologies and making the most of resources generated over many years of research into the canonical Wnt pathway. And results which have the potential to andvance personalised treatment for some forms of cancer. Congrats @andrewwood.bsky.social and collaborators!
Fresh insights reveal how cancer gene mutations drive tumour growth: Andrew Wood (lead of our Degron Cluster) has co-led a team that created a comprehensive map that shows how hundreds of possible mutations in a key cancer gene influence tumour growth nmgn.mrc.ukri.org/news/fresh-i...
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Our Best Models Working Group can offer advice on the use of a range of model systems. The next in our series of posts highlighting our diverse expertise features Dr Alex Whitworth, whose group uses Drosophila models of neurodegenerative diseases. nmgn.mrc.ukri.org/working-grou...
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📢 Job Alert 📢 Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭 Please repost! www.jobs.ac.uk/job/DPW471/s...
Exciting times ahead!
The @mrc-tu.bsky.social and Dept of Biochemistry, @cam.ac.uk, @astra-zeneca.bsky.social, @cruk-si.bsky.social, and the MLC have been awarded a £3.4 million MRC Prosperity Partnership grant to fund research into understanding the toxicity of advanced therapeutics: www.har.mrc.ac.uk/news/new-aca...
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We welcome the government’s effort to provide a clear roadmap for the phasing out of the use of animals in research, while maintaining scientific rigour and safety standards.
Today the UK government has released a strategy to support the development, validation and uptake of alternative methods. Read more: www.gov.uk/government/n...
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Replying to @mrcharwell.bsky.social
We plan to facilitate replacement training at our Advance training centre and lead the @mrcmousenetwork.bsky.social Best Models Working Group, which provides a forum for researchers to learn about alternative models and connect with experts in other systems www.har.mrc.ac.uk/services/rep...
Our guys offering their expertise 😊🙌🏻
Sharing what we know again! Decades of experience distilled into a workshop at #FELASA2025 in which, our senior team talk about how to reduce severity of animal procedures right from the start of a project using GA mice, and limiting welfare issues. #3Rs #AnimalWelfare #training
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Top quality teamwork by @cost-teatime.bsky.social repositories WG to address a key issue in maximising the impact of #Home-cageMonitoring. From the first working group meeting @mrcharwell.bsky.social in Oct’24 to V1 of the preprint in May’25!! Take a sneak peak 👀 here: osf.io/preprints/os...
Another one from the MRC National Mouse Genetics Network #organoids #conference #netweorking
We are co-organising another international conference: Organoids Are Us is a symposium to report and discuss the latest advances in this exciting modality to tackle unanswered biological and clinical questions. For more info nmgn.mrc.ukri.org/news/we-are-...
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Last month was a busy one for the Network's scientists. Some of our MURIDAE cluster members and associates attended the @britishneuro.bsky.social (BNA) #BNA2025 and organised a symposium. Read our short report on the work they showcased! nmgn.mrc.ukri.org/news/bna-fes... @mrcharwell.bsky.social
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Check out this post from @dbogani.bsky.social @mrcharwell.bsky.social about a new tool to assist scientists, policy makers, funders and reviewers in eliminating persistent sex bias in biomedical research: thenode.biologists.com/new-framewor...
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Sponsoring #Pint25 at a packed @oxfordblue.bsky.social and our own @rsbains.bsky.social going through the journey to passive behaviour monitoring powered by #AI @mrcharwell.bsky.social
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Beautiful morning here in Liverpool! If you are attending #BNA2025 @britishneuro.bsky.social check out our symposium this afternoon, Room 3A S21: The MRC National Mouse Genetics Network: Translating genetic findings using preclinical mouse models @mrcmousenetwork.bsky.social
Check out also our post to see how the @mrcharwell.bsky.social contributed to the work and what we think it will me for #preclinical in vivo studies and better #TranslationalResearch outcomes www.har.mrc.ac.uk/news/new-fra...
Using female and male animals in in vivo studies is important to produce reproducible, generalisable and meaningful results using the fewest number of animals. The Sex Inclusive Research Framework (SIRF) helps you check if sex has been fully considered in study design: nc3rs.org.uk/news/sex-inc...
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Very full schedule at our #IMGCglasgow workshop last week, delivered by MitoCluster team @robpitceathly.bsky.social, Carlo Viscomi, @mitogene.bsky.social, and @jim-ca.bsky.social. A pleasure to attend, thanks for the invite @mrcmousenetwork.bsky.social & IMGS! 🧬 #mitochondria #MouseModels #ECR
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Not a network talk but we really enjoyed this one by @davidashbrook.bsky.social on transgenic models of Alzheimer’s Disease on different genetic backgrounds. Loads of data and incredible imaging!
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What a welcome by #Glasgow City Chambers! One of the highlights of this #IMGCGlasgow! @yannherault.bsky.social
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This morning session is Network loaded, starting with Sevda Boyanova from the @ukdri.ac.uk talking about the standardised phenotyping pipelines established for Alzheimer’s and frontotemporal dementia mouse models at the @mrcharwell.bsky.social Great attendance despite the early start! #IMGCGlasgow
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Ageing Cluster member Nicholas Schaum presenting the cluster and the work he’s doing to advance our understanding of the ageing process and the possible intervention points for a healthier life using #mouse cohorts at different age points #IMGCGlasgow #AgeingResearch @mrcharwell.bsky.social
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@lydiateboul.bsky.social and Michelle Stewart lend their decades long experience to highlight the need for rigorous documentation in in vivo studies #MouseGenetics #documentation #ScientificRigour
Parent-of-origin of alleles: an essential variable in in vivo experiments: A new paper from Lydia Teboul and Michelle Stewart highlights the essential role of systematic documentation of genetics and breeding patterns for ensuring reproducibility. www.nature.com/articles/s41...
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Can #AI help communicate #animalresearch? Yes—but responsibly! AI can boost outreach, streamline content, and engage audiences, but ethical use is key: ✅ Transparency & openness ✅ Respect for audiences & animals ✅ Integrity in science communication @costprogramme.bsky.social #SciComm
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Find us at the #FestivalOfTomorrow 2025! We are going to be at The Deanery Academy, in Wichelstowe, Swindon, for the Festival Finale tomorrow and Saturday. Come say hello 👋 and find out how we use models to better understand human disease! Book your tickets now: www.festivaloftomorrow.com
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#Training: Basic lab skills are key to high quality, reproducible research. Our Practical Lab Skills course covers a range of basic skills, including use of equipment, such as centrifuges, balances, and fume hoods We have multiple dates, including 12th March: www.har.mrc.ac.uk/training/cou...
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Our MURIDAE cluster, led by @profantisles.bsky.social is part of an international team that has been awarded £3.5 million to investigate how cognitive decline and premature brain ageing contribute to psychotic disorders like schizophrenia.
Really excited that #MURIDAE @mrcmousenetwork.bsky.social are part of this @wellcometrust.bsky.social funded project 🐭 🧠 nmgn.mrc.ukri.org/news/harness...
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We are #hiring for a number of positions in a new Data Science Team at the @cruk-si.bsky.social that will be delivering the National Mouse Genetics Network data platform, including this Data Science Team Leader role: Deadline: 28th February www.crukscotlandinstitute.ac.uk/careers/comp...
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Happy International Women In Science Day! We have come a long way but there is still so much more to do... The threats for 2025 are real & WE (yes all of us 🫵) as a scientific community must stand up and push back! #ScienceIsPolitical In the halls and websites of the NIH, NASA, HHMI.... 🧪👩🔬✊
The NIH 6 months ago, vs the NIH now. 🧵 Video 👇🏼 NIH 6 months ago. A hallway full of colorful posters profiling women and POC researchers. Shared by @amritalaxshmy.bsky.social on the bird site. 🧪
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We are #hiring for a number of positions in a new Data Science Team at @cruk-si.bsky.social that will be delivering the National Mouse Genetics Network data platform, including this research data architect role: Deadline: 28th February
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We are currently accepting applications for our Graduate Development Programme. Graduates entering this programme will be offered structured training, a real job with real responsibilities from day one, and a direct route to professional accreditation. Deadline: 9th February #GraduateJobs
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Apply now to join our Graduate Development Programme as a Pathology Technician to gain valuable expertise in a wide range of complex in vivo and ex vivo techniques, such as blood collection, assays for clinical chemistry and haematology, and flow cytometry! www.youtube.com/watch?v=kwSl...
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#Training: Our Mouse Necropsy course is aimed at animal technicians & PhD students wanting to learn how to perform a basic standard mouse necropsy and describe gross observations made during this process This course is running in March & June. Book now! www.har.mrc.ac.uk/training/cou...
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A blog on our recent event - the #communication webinar - will be soon online on our website for you to read. Until then, here are some numbers describing its international attendance. Thank you all for participating! @eara.eu @tvvde.bsky.social @i3suporto.bsky.social @costprogramme.bsky.social
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There's still time to complete the straightforward application form for our current Genome Editing Mice for Medicine call before the extended deadline on 31st January to be in with a chance of getting your free, novel, genetically altered mouse model generated
youtube.com/watch?v=277-... Apply to join our Software Development Team through our Graduate Development Programme
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