dbogani.bsky.social

dbogani.bsky.social

@dbogani.bsky.social

37 followers30 following13 posts

dbogani.bsky.social reposted

David Christensen from the Mary Lyon Centre at MRC Harwell @mrcharwell.bsky.social  is joining #BOARD26 to promote understanding of how animal research and other approaches complement each other. #BOARD #EARA #SCICOMM

An elegant approach using a mix of technologies and making the most of resources generated over many years of research into the canonical Wnt pathway. And results which have the potential to andvance personalised treatment for some forms of cancer. Congrats @andrewwood.bsky.social and collaborators!

MRC National Mouse Genetics Network@mrcmousenetwork.bsky.social

Fresh insights reveal how cancer gene mutations drive tumour growth: Andrew Wood (lead of our Degron Cluster) has co-led a team that created a comprehensive map that shows how hundreds of possible mutations in a key cancer gene influence tumour growth nmgn.mrc.ukri.org/news/fresh-i...

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Our Best Models Working Group can offer advice on the use of a range of model systems. The next in our series highlighting our diverse expertise features Dr Andrew Wood, whose lab uses genome editing and targeted protein degradation to study genetic disease using cell lines, organoids, and mice.

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Exciting times ahead!

Mary Lyon Centre at MRC Harwell@mrcharwell.bsky.social

The @mrc-tu.bsky.social and Dept of Biochemistry, @cam.ac.uk, @astra-zeneca.bsky.social, @cruk-si.bsky.social, and the MLC have been awarded a £3.4 million MRC Prosperity Partnership grant to fund research into understanding the toxicity of advanced therapeutics: www.har.mrc.ac.uk/news/new-aca...

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We welcome the government’s effort to provide a clear roadmap for the phasing out of the use of animals in research, while maintaining scientific rigour and safety standards.

NC3Rs@nc3rs.bsky.social

Today the UK government has released a strategy to support the development, validation and uptake of alternative methods. Read more: www.gov.uk/government/n...

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Our guys offering their expertise 😊🙌🏻

Mary Lyon Centre at MRC Harwell@mrcharwell.bsky.social

Sharing what we know again! Decades of experience distilled into a workshop at #FELASA2025 in which, our senior team talk about how to reduce severity of animal procedures right from the start of a project using GA mice, and limiting welfare issues. #3Rs #AnimalWelfare #training

Another one from the MRC National Mouse Genetics Network #organoids #conference #netweorking

MRC National Mouse Genetics Network@mrcmousenetwork.bsky.social

We are co-organising another international conference: Organoids Are Us is a symposium to report and discuss the latest advances in this exciting modality to tackle unanswered biological and clinical questions. For more info nmgn.mrc.ukri.org/news/we-are-...

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Check out also our post to see how the @mrcharwell.bsky.social contributed to the work and what we think it will me for #preclinical in vivo studies and better #TranslationalResearch outcomes www.har.mrc.ac.uk/news/new-fra...

har.mrc.ac.ukNew Framework Aims to Eliminate Sex Bias in Preclinical ResearchAn important new resource for researchers, reviewers, and funders has been developed with major contributions from the Mary Lyon Centre. A group of researchers and policy leaders from organisations in...
NC3Rs@nc3rs.bsky.social

Using female and male animals in in vivo studies is important to produce reproducible, generalisable and meaningful results using the fewest number of animals. The Sex Inclusive Research Framework (SIRF) helps you check if sex has been fully considered in study design: nc3rs.org.uk/news/sex-inc...

@lydiateboul.bsky.social and Michelle Stewart lend their decades long experience to highlight the need for rigorous documentation in in vivo studies #MouseGenetics #documentation #ScientificRigour

Mary Lyon Centre at MRC Harwell@mrcharwell.bsky.social

Parent-of-origin of alleles: an essential variable in in vivo experiments: A new paper from Lydia Teboul and Michelle Stewart highlights the essential role of systematic documentation of genetics and breeding patterns for ensuring reproducibility. www.nature.com/articles/s41...

dbogani.bsky.social reposted

Today we are delighted to host RYUSEI MAEDA from our long standing friend and collaborator Toru Takeo’s lab in Japan. It’s great to find out about his work and interest in science communication as he spends a bit of time in our labs. And it’sa full lecture room! #collaboration #ReproductiveBiology

dbogani.bsky.social reposted

Can #AI help communicate #animalresearch? Yes—but responsibly! AI can boost outreach, streamline content, and engage audiences, but ethical use is key: ✅ Transparency & openness ✅ Respect for audiences & animals ✅ Integrity in science communication @costprogramme.bsky.social #SciComm

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Our MURIDAE cluster, led by @profantisles.bsky.social is part of an international team that has been awarded £3.5 million to investigate how cognitive decline and premature brain ageing contribute to psychotic disorders like schizophrenia.

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Happy International Women In Science Day! We have come a long way but there is still so much more to do... The threats for 2025 are real & WE (yes all of us 🫵) as a scientific community must stand up and push back! #ScienceIsPolitical In the halls and websites of the NIH, NASA, HHMI.... 🧪👩‍🔬✊

Bríd Nic Annaidh ☘️@bridgetmcgann.medsky.social

The NIH 6 months ago, vs the NIH now. 🧵 Video 👇🏼 NIH 6 months ago. A hallway full of colorful posters profiling women and POC researchers. Shared by @amritalaxshmy.bsky.social on the bird site. 🧪

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#Training: Our Mouse Necropsy course is aimed at animal technicians & PhD students wanting to learn how to perform a basic standard mouse necropsy and describe gross observations made during this process This course is running in March & June. Book now! www.har.mrc.ac.uk/training/cou...

har.mrc.ac.ukMouse NecropsyThis course provides practical training in how to perform a basic standard mouse necropsy and describe gross observations made during this process.

dbogani.bsky.social reposted

There's still time to complete the straightforward application form for our current Genome Editing Mice for Medicine call before the extended deadline on 31st January to be in with a chance of getting your free, novel, genetically altered mouse model generated

har.mrc.ac.ukGEMM | Mary Lyon CentreSubmit an application to have your free, novel, genetically altered mouse model generated by the Mary Lyon Centre

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