DEEMteam_Orsay

DEEMteam_Orsay

@deemteam.bsky.social

Diversity, Ecology and Evolution of Microbes (DEEM) team. Posts by David Moreira. #treeoflife #evolution Paris, France https://www.deemteam.fr/en/

1.1K followers248 following117 posts

DEEMteam_Orsay reposted

Now published :) doi.org/10.1093/bib/... and available here github.com/theLabUpstai...

doi.orgCoMR: an integrative scoring pipeline for comprehensive mitochondrial proteome reconstruction across eukaryotesAbstract. Mitochondrial proteome reconstruction from eukaryotic sequence data typically relies on prediction of mitochondrial targeting signals (MTSs). How
Andrew Roger@andrewjroger.bsky.social

Have a novel protist's genome or transcriptome and want to predict it's mitochondrial proteome? Look no further than CoMR, this handy bioinformatic workflow to help you: www.biorxiv.org/content/10.6... #phylogenetics

Ana Gutiérrez-Preciado talking about the microbial communities inhabiting the colorful, arsenic-rich extreme Amuyo Lagoons in northern Chile. #ISSOL2026 #Origins2026

Puri talking about the origin of eukaryotes at the Origins 2026 meeting of the International Society for the Study of the Origins of Life in Paris #ISSOL #Origins2026

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1/ Our new paper in Systematic Biology "Modeling Site-and-Branch-Heterogeneity with GFmix" led by @cgpmcc.bsky.social describes improved ways to model compositional heterogeneity across both sites and branches—an important source of error in deep phylogenomics. doi.org/10.1093/sysb...

doi.orgModeling Site-and-Branch-Heterogeneity with GFmixAbstract. Phylogenetic trees are often inferred from protein sequences sampled from diverse taxa across the tree of life. The compositions of these amino a

DEEMteam_Orsay reposted

DEEMteam_Orsay reposted

Latest output of the European Academy of Microbiology Task Force on Predatory Publishing Practices, initiated and steered by Stipan Jonjić and Ceren Karahan: Fragile Research Systems, Brain Drain, and Predatory Publishing in Under-resourced Countries url: academic.oup.com/microlife/ar...

academic.oup.comFragile Research Systems, Brain Drain, and Predatory Publishing in Under-resourced CountriesAbstract. Many countries with lower research & innovation capacity face persistent constraints in building stable research systems. Chronic underfundin

We have just published a short note on archaeal phylogeny: complex mixture models support a deep placement of Methanonatronarchaeia within Euryarchaea and indicate that three recently described groups (Halorutilales, Afararchaeaceae, and Ordosarchaeia) are actually the same. shorturl.at/5GMpU

DEEMteam_Orsay reposted

Redox distribution of Asgard archaea and co-occurring taxa in microbial mats from an early Proterozoic ecosystem analog | bioRxiv https://www.biorxiv.org/content/10.64898/2026.03.20.713109v1?rss=1

biorxiv.orgRedox distribution of Asgard archaea and co-occurring taxa in microbial mats from an early Proterozoic ecosystem analogEukaryotes originated from the symbiosis of an Asgard archaeon, the alphaproteobacterial ancestor of mitochondria, and possibly additional bacterial contributions. This transition occurred in redox-transition environments such as microbial mats or shallow sediments ~2 billion years ago, when atmospheric oxygen was far lower than today. We investigated Asgard-enriched microbial mats from the low-oxygen, sulfidic Catherine volcano lake (Afar region, Ethiopia), mimicking early Proterozoic conditions. 16S rRNA gene metabarcoding, metagenomics, and metagenome-assembled genome analyses across redox-stratified layers of in situ and mesocosm-maintained mats revealed that Asgardarchaeota thrived in the sulfate-reduction zone, mainly co-occurring with Desulfurobacterota-Myxococcota, among others. Lokiarchaeia and Thorarchaeia preferred anoxic layers. Within Heimdallarchaeia, Heimdallarchaeales were enriched in upper layers, correlating with oxygen-tolerant hydrogenase and sulfate-reduction genes, and Hodarchaeales, in anoxic layers, correlating with methanogenesis. Although reactive-oxygen-species defense mechanisms were widespread, Asgardarchaeota lacked aerobic respiration. These results support the idea that Asgard archaea engaged primarily in syntrophic interactions with sulfate-reducers under early-Earth-like conditions. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, https://ror.org/0472cxd90, 101141745, 787904 Agence Nationale de la Recherche, ANR-23-CE02-0016-01, ANR-22-CE02-0012 Gordon and Betty Moore Foundation, https://ror.org/006wxqw41, GBMF9739

DEEMteam_Orsay reposted

So you are using IQ-TREE to estimate a tree for "deep time" phylogenetics using amino acid alignments. There is a lot of confusion about how to test model fit. Here are some suggestions.

DEEMteam_Orsay reposted

Interested in microbial proteins and their diversity? 🖥️🧬🦠 We have recently released the Amino Acid Sequence Toolkit (AASTK). AASTK is designed to work with the GlobDB to create and work with datasets of protein sequences. AASTK currently consists of 4 tools: - CASM - PASR - CUGO - Meta 1/

We are happy to welcome Xianzhe Gong to the team! His expertise in microbial metabolism and related fields will help us better characterize our collection of MAGs and cultured organisms from many different environments.

2026 kicks off with new faces in the lab! We’re excited to welcome Dina Boukheloua, Eliott Tempez, and Pierre van Ettro, who will be working on endosymbionts in protists, archaeal genome evolution, and aquatic amoeba diversity. Welcome to the team!

Near the end of the year, we are excited to welcome three new members to the team: Inés Ochoa (PhD student), and Charley McCarthy and Eva Zanditenas (postdocs). They will work on different projects using experimental and bioinformatics approaches.

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Microbial eukaryotes keep challenging assumptions about eukaryotic cell and genome biology. Our upcoming workshop explores the frontier of protist genomics and how it shapes cell biology, ecology and evolution. Please save the date! Talks, posters and ECR events Websites and details coming soon

DEEMteam_Orsay reposted

Those interested in performing maximum likelihood phylogenomic analysis on data sets made up of eukaryotic nuclear genes using site heterogeneous mixture models like C60, I suggest you use the ELM model in IQ-TREE instead of the LG model /1

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DEEMteam_Orsay reposted

How did life begin, and why does it matter? Scientists are tracing early microbial life–from LUCA to multicellularity–to unlock insights for biotech, climate science and even space exploration. Read the article: asm.org/articles/202...

asm.orgEarly Microbial Evolution | ASM.orgHow did life begin, and why does it matter? Scientists are tracing early microbial life—from LUCA to multicellularity—to unlock insights for biotech, climate science and even space exploration.

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DEEMteam_Orsay reposted

Check out our paper on intricate nested interactions between viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts. Excellent collaboration with @deemteam.bsky.social, @anagtz.bsky.social and Michail Yakimov Free access link: rdcu.be/eLtCH 🧵 by @yifanzhou.bsky.social 👇

DEEMteam_Orsay reposted

Ponce-Toledo et al. confirm the presence, homology, and monophyletic origin of the SELMA protein complex in Cryptophyta, Alveolata, Stramenopiles, and Haptophyta, shedding light on the evolution of photosynthetic eukaryotes. 🔗 doi.org/10.1093/molbev/msaf167 #evobio #molbio

doi.orgMolecular Phylogeny of the SELMA Translocation Machinery Recounts the Evolution of Complex Photosynthetic EukaryotesAbstract. Photosynthetic eukaryotes and their relatives are the result of an intricate evolutionary history involving a series of plastid acquisitions thro