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*** Call for papers deadline extended *** Submit your latest #Paediatric #GeneticDiseases paper to be included in our next special issue. The deadline has been extended to 7 December 2026. Find out more today 👇️ tinyurl.com/3b8zscaz
DMM Journal
@dmmjournal.bsky.social
Disease Models & Mechanisms - discovery for human health. A @biologists.bsky.social Open Access journal that publishes human disease research.
3.4K followers115 following608 posts
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*** Call for papers deadline extended *** Submit your latest #Paediatric #GeneticDiseases paper to be included in our next special issue. The deadline has been extended to 7 December 2026. Find out more today 👇️ tinyurl.com/3b8zscaz
There is still plenty of time to submit your latest #Paediatric #GeneticDiseases paper to be included in our next special issue. Deadline: 7 December 2026. Find out more 👇️ tinyurl.com/msmfhc2e
A knockout #MouseModel reveals that CRPPA deficiency is associated with mitochondrial dysfunction involving the cAMP-PKA-DRP1 pathway. Read the article by Jihang Luo: doi.org/10.1242/dmm....
A bioengineered platform reveals progressive impairment of skeletal muscles by metabolic dysfunction-associated steatotic liver disease-derived factors. Check out the Research Article by Armando Cortés-Reséndiz & co: doi.org/10.1242/dmm....
Check out the #FirstPerson interview with Armando, a PhD student in the lab of Javier Ramón-Azcón at Institute for Bioengineering of Catalonia (IBEC), developing human in vitro models to investigate complex disease mechanisms and organ–organ interactions. doi.org/10.1242/dmm....
We are delighted to support the Milner Therapeutics Institute seminar series. Don't miss the next seminar on 18 November, with a focus on #neurodegeneration. In the meantime, read DMM's neurodegeneration subject collection: journals.biologists.com/dmm/collecti...
Milner Seminar: Focus on neurodegeneration 🧠 🗓️ 18 November ⏰ 4-5pm 📍 Jeffrey Cheah Biomedical Centre Speakers: Maura Malpetti and John Skidmore from University of Cambridge. Special thanks to our sponsors DMM Journal! 🔗 Register: https://ow.ly/VXhT50ZRmce
We are pleased to be a @reviewcommons.org affiliate journal. Our Academic Editors are happy to consider transfers from Review Commons. Find out more about the platform and why authors chose it: www.embo.org/features/why...
For your #WeekendRead - Tracey Murray Stewart and colleagues present an improved mouse model of #SnyderRobinsonSyndrome, providing a robust platform for therapy testing. Read and share the article for free doi.org/10.1242/dmm....
Today is #BreastCancerAwareness #WearItPink day. In our interview with Funmi Olopade, she talks about her serendipitous research path, improving care for breast cancer patients and the heroism of women in genetics. doi.org/10.1242/dmm.... @breastcancernow.bsky.social #BCAM
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Meet Patricia Carnicero, an EACR Travel Fellowship recipients! The EACR Travel Fellowship supports cancer researchers in building connections and advancing their science in new, collaborative settings. 🌍 Read more here: https://magazine.eacr.org/patricia-carniceros-travel-fellowship/
Claes Fryklund & co use longitudinal metabolic phenotyping to identify a fixed-dose streptozotocin protocol that produces a stable type 2 diabetes-like phenotype in high-fat-diet-fed mice. Check out this article for free in DMM: doi.org/10.1242/dmm....
‘Why is publishing so expensive?’ This year’s theme for #OAweek is #TheCostOfKnowledge - an opportunity to revisit the Editorial where DMM, a fully Open Access journal, is transparent about its publishing finances: journals.biologists.com/dmm/article/...
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Double Blow: Link revealed between gene loss causing Prader-Willi syndrome & placental blood vessel development 📸 Anna E. Webberley & Raquel Boque-Sastre et al @profantisles.bsky.social @cumedicengage.bsky.social in @dmmjournal.bsky.social ➡️ bpod.org.uk/archive/2026... + @antdlewis.bsky.social
We're still celebrating #OAweek: Our subject collections of #openaccess reviews and research articles make it easy to browse your favourite topics: journals.biologists.com/dmm/collecti...
Ignacio Simó and colleagues find polyQ-expanded ataxin-3 is associated with mitochondrial alterations in #MachadoJosephDisease Read the Research Article for free: doi.org/10.1242/dmm....
To find out more about this research, check out the #FirstPerson interview with Ignacio, a postdoc in the lab of Angela Laird at Macquarie University, investigating mitochondrial dysfunction, cellular metabolism and m6A RNA regulation doi.org/10.1242/dmm....
Celebrate #OAweek 2026 with DMM. Learn more about DMM's Open Access policies journals.biologists.com/dmm/pages/op...
Female-specific alterations in insulin dynamics are associated with glucose tolerance in a Glut1DS mouse model Check out the article by Tamio Furuse & co: doi.org/10.1242/dmm....
Thank you to organisers James Amatruda @amatrudalab.bsky.social , Pratiti (Mimi) Bandopadhayay @bandolab.bsky.social , Ana Banito and Elaine Mardis and everyone who joined us last week for our meeting on Innovative Preclinical Models for Pediatric Cancer Research #DMM2026cancer
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Register for a free scientific storytelling workshop @the-node.bsky.social, @prelights.bsky.social & @focalplane.bsky.social are excited to announce our free half-day workshop on scientific storytelling! Join us on 10 November 2026 from 13:00-17:00 GMT. #ScienceStorytelling #ECR #Scicomm
For your #WeekendRead this #BreastCancerAwarenessMonth - Functional exploration of copy number alterations in a Drosophila model of triple-negative breast cancer. Read the article by Diaz et al: doi.org/10.1242/dmm....
Eduardo Vieira Neto and colleagues characterise the #cardiomyopathy developed by a mouse model carrying a mutation in the β-subunit of mitochondrial trifunctional protein Read and share for free: doi.org/10.1242/dmm....
DMM Editors - Jim Amatruda, Steve Clapcote, Elaine Mardis, Liz Patton and Karen Liu - at the DMM meeting earlier this week, exploring Nationwide Children’s Hospital @nationwidekids.bsky.social in Columbus, Ohio. www.nationwidechildrens.org
Thank you to everyone who made DMM’s meeting on Innovative Preclinical Models for Pediatric Cancer Research a success! See our wonderful venue all set for presentations below - Nationwide Children’s Hospital Conference Center - and Downtown Columbus, Ohio in the sun ☀️ www.nationwidechildrens.org
Luiza Albuquerque Coelho & co investigate progressive impairment of muscle regeneration in the dy2J mouse model of LAMA2-related muscular dystrophy. Read the Research Article for free in DMM: doi.org/10.1242/dmm....
Find out more about this research in the #FirstPerson interview with Luiza Coelho, now a Master's student investigating muscle regeneration in health and disease and the factors that modulate this process. doi.org/10.1242/dmm....
Fuelling repair: #metabolic regulation of alveolar type 2 cell fate in lung regeneration and disease Check out this #Review by Sophia Wugk & co. doi.org/10.1242/dmm....
This #BreastCancerAwarenessMonth, check out the article by Jun Nakayama and colleagues, who identified two cancer stem cell-like populations in triple-negative breast cancer xenografts. doi.org/10.1242/dmm.... #BCAM @breastcancernow.bsky.social
Melis Kose & co describe how biomarkers, non-invasive functional testing, tissue-based assays, and genomic and omics approaches are combined to diagnose primary mitochondrial disease in current clinical practice. Read the Review for free: doi.org/10.1242/dmm....
For your #WeekendRead – check out the new #DMMPerspective by Forn-Cuni et al. on zebrafish cancer models. doi.org/10.1242/dmm....
October is #BreastCancerAwarenessMonth We are revisiting DMM content that centres breast cancer, starting with an #EditorsChoice: Nadia Alissa & co investigated CCL2 as a potential regulator of skeletal muscle wasting in breast cancer doi.org/10.1242/dmm.... @breastcancernow.bsky.social #BCAM
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In 2027, @dev-journal.bsky.social, @jcellsci.bsky.social and @dmmjournal.bsky.social will be organising a meeting on #metabolism. Sign up for registration and programme updates at biologists.com/meetings/met... #BiologistsMetabolism
September’s #EditorsChoice from Hynes et al. @MUN_Science on sex-dependent mild cardiac dysfunction and neurometabolic abnormalities in a model of Huntington's disease. Check out the article in DMM for free: doi.org/10.1242/dmm....
Read the Editor’s Choice post accompanying this article doi.org/10.1242/dmm....
Paediatric Genetic Diseases: Models, Mechanisms & Therapies - Read the #Editorial by Senior Editor Kirsty Hooper who discusses recent research in this area doi.org/10.1242/dmm....
DMM has launched a Special Issue focused on paediatric genetic diseases – submit your paper by 7 December via tinyurl.com/msmfhc2e
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📢 We are pleased to announce the final session of the 2026 @cambridgeflyclub.bsky.social seminar series, taking place on the 7th of October at 4 PM in the Gurdon Institute tea room.
Issue 9 is all yours! On the cover: Bioengineered human skeletal muscle from a metabolic dysfunction-associated steatohepatitis (MASH)-like liver model. See Research article by Cortés-Reséndiz et al. doi.org/10.1242/dmm.....
Sonnberger & co demonstrate for the first time in a human macrophage model that the host factor gasdermin D and the fungal peptide toxin candidalysin have distinct roles in triggering pyroptosis and inducing lytic host cell death. Read and share the article for free: doi.org/10.1242/dmm....
For your #WeekendRead - Ruth A. Howe & co propose a panel of pulmonary clinical isolates representing major Mab subspecies and phenotypes for lung research. Read and share the Resources & Methods article for free: doi.org/10.1242/dmm....
To find out more about this research, check out the #FirstPerson interview with Ruth Howe, a Clinical and Research Fellow in the lab of Gyanu Lamichhane at Johns Hopkins University, Baltimore, MD, USA doi.org/10.1242/dmm....
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Really looking forward to this meeting! Join us if you're interested in the intersection between metabolism, development and disease!
Save the date - @dev-journal.bsky.social, @jcellsci.bsky.social and @dmmjournal.bsky.social are holding a meeting on #Metabolism 📅21 – 23 June 2027 📍St Mary’s Marylebone, London, UK Register your interest for #BiologistsMetabolism now www.biologists.com/meetings/met...
Our Editor will be attending the IPSC 20th Anniversary Symposium in Kyoto. Reach out with any questions about publishing in @dmmjournal.bsky.social, @biologists.bsky.social's charitable activities and more. @isscr.org
Maaike van Putten @oligogirl.bsky.social & co develop four new mouse models of Duchenne muscular dystrophy with clinically relevant exon deletions in the human DMD gene. Read the Resources & Methods article for free: doi.org/10.1242/dmm....
This article is a @reviewcommons.org transfer. Find out more about Review Commons and the transfer to affiliate journals including @dmmjournal.bsky.social. www.reviewcommons.org
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Did you ever wonder how the leopard got its spots? Or how the zebra got its stripes? Wonder no more! In this #Short, @benswedlund.bsky.social talks about his #preprint describing reaction-diffusion architecture for engineering self-organised patterns in mammalian cells. 🎙️⬇️ youtu.be/_HMbr4KE1PI?...