Steve Moss

I've put together a blog post on local continuous development tooling for Kubernetes that allows you to shorten the feedback loop and iterate much more quickly. See here gawbul.medium.com/optimising-k... #kubernetes #skaffold #development #deployment #helm #testing #verification #tooling

I am truly honoured to have been awarded this prestigous prize. I have great pride of the science I have been involved with - sometimes led - and huge thanks to the many scientists I have worked over the last four decades to make this possible Stay tuned for Nov 10th when more info available

Rustup 1.29.2 has been released. This is a small release which only updates the rustls-webpki and webpki-root-certs dependencies to remove the compromised eMudhra intermediate certificates. See the announcement for details: blog.rust-lang.org/2026/10/20/R...

For users of our new FTP space: ftp.ebi.ac.uk/pub/ensemblo... - reminder that we are retiring the species name based directory structure this week! More info on our blog www.ensembl.info/2026/10/08/r...

👩🏽‍🔬 Go 1.27.3 and 1.26.10 are released! 🔐 Security: Includes 1 security fixes to the standard library. 🗣 Announcement: https://groups.google.com/g/golang-announce/c/66pojueaQek/m/tmWX2Pq9AgAJ 📦 Download: https://go.dev/dl/#go1.27.3 #golang

Rust 1.99.1 has been released. This point release fixes a missing wcslen symbol on some targets, a miscompilation of FFI bool return values on x86_64, and a rust-lld issue on macOS. See the blog post for details: blog.rust-lang.org/2026/10/15/R...

The @embl.org PhD programme closes in 48 hours - you still have time to rush in an application if you are a science, maths or computer science undergraduate wanting to do a PhD in one of the world's leading biology and AI institutes www.embl.org/about/info/e...

🎉 Go 1.27.2 and 1.26.9 are released! 🔐 Security: Includes 15 security fixes to the standard library and the toolchain. 📡 Announcement: https://groups.google.com/g/golang-announce/c/U2fTuyDJznI/m/bAPU-QKAAQAJ 📦 Download: https://go.dev/dl/#go1.27.2 #golang

Ready for the fireside chat that @lizthegrey.com and I are doing today? It’s titled “Observability Engineering: What’s Next?” And it’s going to be a wild ride. Bring your o11y questions for our Q&A session! I might be spooky but observability doesn’t have to be 🫡 luma.com/srenl?e=evt-...

Rust 1.99.0 has been released! 🦀 🌈 This release includes extern "C" variadics (VaList), VecDeque::retain_back, Box::{into,from}_non_null, Vec::{into,from}_parts, std::fs::set_times, Layout::for_value_raw, and more! ✨️ Check out the blog post for all the details: blog.rust-lang.org/2026/10/01/R...

Your SLOs and telemetry are working. Now leadership wants to know why the observability bill went up. My last session was about designing SLOs that mean something. This week's Masterclass is about the bill that follows, and most of it comes down to inefficient sampling.

Google is killing off Gemini’s Gems in favor of ‘skills’

Students sometimes ask me if it still makes sense, in this accelerating age, to pursue a PhD in AI. Perhaps counterintuitively, I think it's a great time to do so. I wrote up some thoughts on this here: web.mit.edu/phillipi/www...

O11yDay London is happening October 6–7 at Convene Bishopsgate. 🐝 Two days of practitioners talking about AI in production. Hands-on workshops, no sales decks. If you're figuring this stuff out in real time, come compare notes. www.honeycomb.io/events/o11yd... #o11yday #observability #london

Two full days at Convene Bishopsgate: workshops on the 6th, the full conference on the 7th. If you're in London that week, come to the demo and tell me what's breaking in your own systems right now. We'll be taking notes, not just talking at you. Register: go.hny.co/4fgpZPd

Most vendors will show you a demo of what their product does. Fewer explain why it's built the way it is, what they got wrong along the way, and what they'd change now with hindsight. I'm facilitating a session at O11yDay London on Oct 7 about how we actually built Honeycomb's latest features.

Slides for my @pyconau.bsky.social keynote about scaling our systems from 30 to 70 PRs merged per day at @honeycomb.io: drive.google.com/file/d/1CaO6...

Your SLO breaks. Can your tooling tell you why, or just that something is wrong and customers are suffering? SLOs were popularised by the SRE book a decade ago. Most teams *still* aren't using them well.

Ensembl archive sites are currently under very heavy load, causing failures and slow performance. Sorry for the disruptions, we're working on it. Workaround for Ensembl 116 (June 2026): use the Ensembl 115 (Sep 2025) archive instead - sep2025.archive.ensembl.org/index.html

We’re a top 20 university yet again 👏 We’ve placed joint 18th in The Times and Sunday Times Good University Guide 2027 🎉 We're proud to continue being among the very best universities in the country! Read the full story: https://tinyurl.com/nhd9j987

I wrote a new piece yesterday, called "Confessions of an Unrepentant Slop Snob", about my escalating rage at AI-generated text. It includes a framework for thinking about when AI involvement is fine -- just another tool -- and when it lands as a violation. charity.wtf/p/confession...

Rust 1.98.1 has been released. This release fixes a possible miscompilation in vtable generation. Under certain circumstances, Rust 1.98.0 incorrectly puts a null pointer where a function pointer should be. See the blog post for details: blog.rust-lang.org/2026/09/03/R...

Tailscale without Tailscale, by Tailscale. Meet tailcat. tailcat is an open-source Go package and CLI that lets you use Tailscale’s data plane without the control plane. No accounts, logins, admins, or IPs to manage. Learn more → tailscale.com/blog/tailcat...

🎉 Go 1.27.1 and 1.26.8 are released! 🗣 Announcement: https://groups.google.com/g/golang-announce/c/QiTRm-HGGtI/m/cpfkLlpMAQAJ 🗃 Download: https://go.dev/dl/#go1.27.1 #golang

“Generic Methods” by Mark Freeman — https://go.dev/blog/generic-methods #golang

We started a Reproducibility Network for Computational Biology! 🎉 🥳 🍾 Improving research quality is the main aim. There will be opportunities to get involved later in the year as a general member or position on the committee. More details here […] [Original post on genomic.social]

How is using Docker containers any better than strict descriptiuons of all packages with requirements.txt (Python) or Renv (R)? Let's discuss. https://genomespot.blogspot.com/2026/08/on-computational-reproducibility-surely.html #Bioinformatics #Reproducibility

From BSKY & colleagues in @plos.org #Computational #Biology | Ten quick tips for causal analysis of biomedical omics data | #Bioinformatics #Education #PLOSCBQT #Omics #Genomics | CC/ @janawolfberlin.bsky.social | 🧬🖥️🧪🔓 ⬇️ journals.plos.org/ploscompbiol...

From @plos.org #Computational #Biology | Eleven quick tips for Biomedical Federated Learning | #Bioinformatics #Education #PLOSCBQT #ML #FL CC/ @ppalagi.bsky.social | 🧬🖥️🧪🔓 ⬇️ journals.plos.org/ploscompbiol...

From @plos.org #Computational #Biology | Ten simple rules for effective use of generative AI for code development in environmental science | #Education #Bioinformatics #PLOSCBTSR #GenAI #AI #EnvironmentalScience | 🧬🖥️🧪🔓 CC/ @skissler.bsky.social ⬇️ journals.plos.org/ploscompbiol...

Just submitted my PhD thesis on algorithms for fast, large-scale k-mer-based sequence analysis. It's now available to read at phd.martayan.org Take a look and feel free to share! #Bioinformatics #PhDone

the first in a 3-part series on @honeycomb.io's AI norms and values is up. this one is called "How We Do Business at Honeycomb." www.honeycomb.io/blog/ai-norm... values are not supposed to be aspirational slogans. values should codify how things actually work. this is how it works at ours.

Rust 1.98.0 has been released! 🌈 🦀 This release includes algebraic floating point methods, NumBuffer for integer formatting, substr_range/subslice_range, strip_circumfix, Atomic<T>::from_mut, and more. ✨ Check out the blog post for all the details: blog.rust-lang.org/2026/08/20/R...

⚠️ A few hours ago, a malicious crate was discovered on crates.​io which spread as a dependency of `arrayref` and some other crates, likely due to compromised credentials. The affected versions have been deleted. For details and how to see if you are impacted, see: blog.rust-lang.org/2026/08/20/s...

“Go 1.27 is released” by Nicholas Husin, on behalf of the Go team — https://go.dev/blog/go1.27 #golang

🎊 Go 1.27.0 is released! 🗒️ Release notes: https://go.dev/doc/go1.27 📦 Download: https://go.dev/dl/#go1.27.0 #golang

🎉 Go 1.26.7 and 1.25.14 are released! 📡 Announcement: https://groups.google.com/g/golang-announce/c/qA6Vpj2UA-4/m/87iz6vfSBAAJ ⬇️ Download: https://go.dev/dl/#go1.26.7 #golang

Exciting opportunity to work with Ensembl microbes! We are seeking a bioinformatician to help us develop and maintain high-quality genome resources for microbial research communities. More info: zurl.co/hdKpk #Jobs #bioinformatics

🎊 Go 1.26.6 and 1.25.13 are released! 🔐 Security: Includes 10 security fixes to the standard library and the toolchain. 🔈 Announcement: https://groups.google.com/g/golang-announce/c/94pEornpRlI/m/_JhCbsOZBAAJ 📦 Download: https://go.dev/dl/#go1.26.6 #golang

AI is your newest teammate—a hyper-productive contributor that requires strong guardrails to succeed. Read more on why this partnership makes your choice of programming language more important than ever. developers.googleblog.com/why-go-is-an...

Ensembl has moved! We are ahead of schedule and all sites now point to the new Ensembl at ensembl.org. It is a major milestone in our 26 year long project! 🧬🧬🧬 Refresh your browser cache for our sites if you find an error this week ⚙️

Ensembl is moving this week! 🧬 Links will point you to the new Ensembl. The default site will be ensembl.org for all species from across the tree of life. We’re starting with the Ensembl Genomes sites, and we’ll end with the Ensembl 116 site.

How is AI (artificial intelligence) used in genomics? AI is helping researchers analyse genomic data, identify patterns and generate new insights into health. Swipe through the images below to learn how AI is supporting genomic research and helping us better understand our DNA.

Rust 1.97.1 has been released. This release fixes a miscompilation in an LLVM optimization. This newly discovered issue has existed since 1.87.0, but was unlikely to lead to an actual miscompilation until a change in 1.97.0. See the blog post for details: blog.rust-lang.org/2026/07/16/R...

Rust 1.97.0 has been released! 🌈 ✨ 🦀 Some of the highlights are new symbol mangling, a new Cargo setting for Rust warnings, linker output, and new integer methods: bit_width, {lowest,highest}_one, isolate_{lowest,highest}_one. Check out the blog post for details: blog.rust-lang.org/2026/07/09/R...

🎉 Go 1.26.5 and 1.25.12 are released! 🔐 Security: Includes 2 security fixes to the standard library. 🗣 Announcement: https://groups.google.com/g/golang-announce/c/OrmQE_Yp5Sc/m/G9tnwhteAAAJ 📦 Download: https://go.dev/dl/#go1.26.5 #golang

People really hate AI mandates -- unsurprisingly, since most are terrible. But they don't have to be. Used wisely, the mandate is an effective tool for driving and funding organizational change. More in my piece, "In defense of AI mandates." charitydotwtf.substack.com/p/in-defense...

Rust 1.96.1 has been released. This point release includes a fix for a miscompilation in a MIR optimization, a fix for http timeouts in Cargo, and patches the recent vulnerabilities in libssh2 which is used as part of Cargo. See the blog post for details: blog.rust-lang.org/2026/06/30/R...

New Ensembl FTP users, heads up! 

The FTP structure for the new site has been updated. The species name-based structure will be retired in August 2026. Overlap dumps are provided to help while you rework existing pipelines. Read more on our blog: zurl.co/sSbPj

as promised, here is my post on AI and ethics. I think unilateral disarmament in the face of powerful new tools is neither wise nor effective. I think those of us in tech have a particular responsibility to engage, participate and build better solutions. charitydotwtf.substack.com/p/make-ai-bo...

First pre-print from the lab, a collaborative effort led by Jess Bourn @bournsupremacy.bsky.social, a fantastic PhD in my group. We resolve a key problem in development + evolution: how do we quantify heterochrony and link temporal variation to phenotype? www.biorxiv.org/content/10.6...