Jordan Ward

Jordan Ward

@gotworms.bsky.social

Associate prof, UC Santa Cruz (Go Slugs!). Worm wrangler interested in mechanisms of developmental timing, ECMs and parasites. Love good food/drink, trail running, and my wife+2 silly cats. G3 associate editor and incoming WormBoard President.

523 followers532 following74 posts

Great to see this beautiful story out!

Max Heiman@heiman.bsky.social

Now published in @currentbiology.bsky.social ! Leland Wexler identified a very big, previously unstudied secreted protein that attaches neuronal cilia to glia. authors.elsevier.com/sd/article/S...

So excited to see this fun collaboration with Andrew Chisholm out in the world. So much to do with this aECM toolkit for matrix biology, aging, stress, pathogenesis research! Found a striking diversity of localization patterns for different components.

PLOS Biology@plosbiology.org

Barrier #epithelia are protected by apical extracellular matrices (aECMs). This Resource by @gotworms.bsky.social @ucscscience.bsky.social &co generates a toolkit of 105 fluorescently tagged aECM components and defines reference markers for key substructures. 🧪 #AcademicSky #Celegans plos.io/4sggBS0

Great to see this beautiful work published!

Pujol lab@pujol-lab.bsky.social

Spatial memory in tissue architecture: how a transient extracellular scaffold propagates positional information #aECM #Celegans @plos.org 🙏to talented Sophie Mazzoli @ciml.bsky.social @centuri-ls.bsky.social @univ-amu.fr & great collaborations @dynamo-lab.bsky.social @meera-sundaram.bsky.social 🧵👇

Jordan Ward reposted

Sad to see that Don passed, he was a legend and a big part of why our community is so special. 🤯 20% of the collection?!!

cgc-worms.bsky.social@cgc-worms.bsky.social

The worm community has lost a true legend with the passing of Don Moerman. Don's impact on C. elegans research is beyond measure. A friend to many of us here in MN, his work has been invaluable, contributing >5,400 strains (VC & DM) to the CGC, 20% of our collection!

Great to see this out. Practical guidance on how to use protein depletion systems in C. elegans

Genetics Society of America@genetics-gsa.bsky.social

Check out this review in #GENETICS from @gotworms.bsky.social, @cgc-worms.bsky.social, and others describing the first release in the Curated Special Collections for #Celegans, highlighting protein degradation systems and how to achieve targeted protein deletion in #nematode #worms. buff.ly/lEaf2T2

Jordan Ward reposted

I am reviewing a simply amazing paper from a relatively young US-based lab, which is in danger of shutting its doors later this year. My emotions are all over the place. The fact that this does not uniquely identify the lab I’m referring to just deepens the tragedy of this moment in US science.

Excited to see this out in the world. The CGC is launching a curated strains collection, the first being protein degradation systems and this is a pilot primer to pair with it authored by myself, Dave Reiner, Ann Rougvie, and Aric Daul. We review the state of the field and provide use guidance (1)

The CGC has added some cool functionality to improve the searchability of the site to help find appropriate strains for your research. We are working to create a consistent nomenclature. More collections to come in the future. Folks can ask questions on Worm Slack, the Alliance forum, or here! (2)

Jordan Ward reposted

What tools do we need to start engineering #aging and #longevity ? A🧵about something we've been cooking up in lab with Jeremy Vicencio at the @crg.eu : technology that lets us reach inside living animals and precisely dial multiple proteins' levels up and down. 1/10

So excited to see this work out! This was one of the first projects when I started my lab! An awesome collaboration with @labgrosshans.bsky.social and @partchlab.bsky.social!

Grosshans Lab@labgrosshans.bsky.social

And the next one: dx.doi.org/10.1038/s44318-025-00585-z . Super-fun collaboration with @partchlab.bsky.social & @gotworms.bsky.social to find similarities between developmental and circadian clocks – supported by @fmiscience.bsky.social Facilities and, financially, @snsf.ch and @erc.europa.eu . 1/n

Jordan Ward reposted

For the life of me, I cannot fathom the rationale for any of this. Utter wanton destruction of one of the best research ecosystems in the world.

Liz Essley Whyte@lizessleywhyte.bsky.social

NEW The White House is blocking the NIH from awarding new research grants for the rest of the fiscal year Chokes off billions in research funding Gift link www.wsj.com/politics/pol... with @nidhisubs.bsky.social

Jordan Ward reposted

There is so much cool #aECM work going on but most of the researchers don’t know or talk to each other; this is an attempt to change that! Link below

Pujol lab@pujol-lab.bsky.social

... a new virtual seminar series on apical extracellular matrix #aECM on different #organisms 🪱🪰🐁🌱🦠will start in Fall 2025, with short talks and discussions If you are interested 👉https://forms.gle/Y6UjbnXPH1pDHAE97 @meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social

Am so excited about this series. The virtual worm skin workshop was one of the best meetings for my lab and getting more model systems will be🔥

Pujol lab@pujol-lab.bsky.social

... a new virtual seminar series on apical extracellular matrix #aECM on different #organisms 🪱🪰🐁🌱🦠will start in Fall 2025, with short talks and discussions If you are interested 👉https://forms.gle/Y6UjbnXPH1pDHAE97 @meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social

🤯🤯🤯

Meera Sundaram@meera-sundaram.bsky.social

Catching up on more #aECM at #worm25 by watching the online videos: Physiology1 Talk23 from Jonathan Hodgkin provided evidence that, via social interactions, worms can transfer surface glycans (« BIM ») between each other to affect pathogen sensitivity. So cool!

Thanks for the shout out @meera-sundaram.bsky.social ! This was such a fun project! 101 knock-ins and counting and they all had such cool and unique localization pattern and substructures!

Meera Sundaram@meera-sundaram.bsky.social

Up on biorxiv! The tour de force protein tagging atlas for the #Celegans cuticle #aECM - from Jordan Ward @gotworms.bsky.social and Andrew Chisholm labs. So many beautiful images of cuticle collagen substructures !! www.biorxiv.org/content/10.1...

Really excited about this collaborative work and a great experience with Review Commons

Review Commons@reviewcommons.org

A conserved chronobiological complex times C. elegans development. Latest research from the Ward lab @gotworms.bsky.social @ucsantacruz.bsky.social and Grosshans lab @labgrosshans.bsky.social @fmiscience.bsky.social

Glad I could play a small part in this cool story!

Pujol lab@pujol-lab.bsky.social

Our new paper out @plos.org @ciml.bsky.social @centuri-ls.bsky.social Fantastic collaborations 👏Antonina Andreeva #EBI-EMBL, Claire Valotteau @DyNaMo @felix_rico, Andrew Chisholm, Jordan Ward @gotworms.bsky.social, and great discussions with @meera-sundaram.bsky.social dx.plos.org/10.1371/jour...

Jordan Ward reposted

WTAF

Alt NIH Bluesky 🧪@altnih4science.bsky.social

More hits to #NIH: "The Trump administration has imposed a new restriction on employment that could push out thousands of NIH’s senior scientists: The agency cannot retain scientists in 1-year to 4-year positions that have long been routinely renewed." 🧪 @jocelynkaiser.bsky.social at @science.org

Jordan Ward reposted

Tomorrow I’m having a conversation with Senator Murray about NIH on my public Instagram - @sciencewhizliz. The timing could shift a bit due to the senate floor schedule. So if that happens we will adjust and share the recording!

Exactly. My R35 council meeting has been cancelled without clear rescheduling. No idea when I know if I can keep lab funded. MRAC study section I reviewed for cancelled at last minute. So much wasted effort and anxiety for folks.

Annika Barber@annikabarber.bsky.social

This is a distinction without a difference. If there are no council meetings, funding is still being withheld and reviewer time is being wasted.

Jordan Ward reposted

Please share: @delauro.house.gov is cochair of the US House Congressional Rapid Response Task Force and Litigation Working Group. They are looking for instances where the impoundment and restriction of NIH/NSF funds is having a negative impact. Submit examples here delauro.house.gov/constituent-...

delauro.house.gov2025 Federal Financial Assistance FreezeOn Monday, January 27th, 2025, President Trump issued an order to freeze virtually all of approved and legally required federal funding.

Really important development. I’ve got my MIRA app that should be discussed on Feb 6. Need this to keep the lab going.

Jeremy Berg@jeremymberg.bsky.social

SOME GOOD NEWS ABOUT NIH FUNDING Closed sessions of institute and center Advisory Counsel meetings are now permitted. This is where grant applications are discussed and approved for potential funding. Open sessions where there are public presentations and discussions are still not allowed.