Houming Chen

Nice work by @cellsensing.bsky.social Glycan recognition by a plant damage-sensing immune receptor www.science.org/doi/10.1126/...

📣 Job alert! 2 Positions starting 2027. PhD position with me and @bayerlab.bsky.social on Robustness of embryonic and stomatal development, part of @greenrobust.de Postdoc position on the regulation of cell state, following up on some exciting snRNAseq dat! Apply now or share! #PlantSciJob

It took some time, but we are thrilled to present the first major outcome of our @erc.europa.eu ERC DIRNDL AdG project: Evgeniya Pukhovaya @epukh.bsky.social and others in our team describe the discovery of a mechanism for polar protein targeting in plants (1/13) www.biorxiv.org/content/10.6...

🌱🧬ARFs are ancient DNA-binding proteins that predate auxin. Signaling evolved by linking them to a degradation-based system, adding responsiveness while keeping core function. A model for how plant networks evolve. #plantscience @newphyt.bsky.social nph.onlinelibrary.wiley.com/doi/10.1111/...

Our latest preprint is online. www.biorxiv.org/content/10.6... Our exciting data show that embryonic patterning in Arabidopsis is kick-started by differential sensitivity towards auxin and not by differential distribution of auxin.

Fresh preprint online from our group! We find that stomatal maturation IS possible in the embryo, when they lack ERECTA signaling, but then still, only at the cotyledon tip. A thread. www.biorxiv.org/content/10.6...

New in @embojournal.org from @birgitkemmerling.bsky.social's lab: HIR2 assembles into giant ring-like complexes at the plasma membrane, shaping receptor dynamics and immune signalling. Genetics + biochem + super-res imaging + AF3 modelling, all in one! Check it out👇 link.springer.com/article/10.1...

The RTS (Swiss TV) visited our lab and talked about our recent work on natural variation for suberin in the News yesterday evening! (In French)

Team effort from @fxrico.bsky.social, Oded, Pierre, Andrea, @hmchen93.bsky.social, Larissa now out in @pnas.org The Kelch phosphatase BSU1 is a PP1-like serine/threonine phosphatase involved in cell cycle regulation, not a tyrosine phosphatase in brassinosteroid signaling 👍 doi.org/10.1073/pnas...

It’s FINALLY out! We investigated the natural variations for endodermal suberin and identified SUBER GENE1 (SBG1)- Type One Protein Phosphatases (TOPPs) as a novel module that regulates endodermal suberization. @mariebarberon.bsky.social rdcu.be/fgU6g #PlantScience

New preprint out! Zhoubo Hu et al "A redox-regulated RCC1-like protein controls catalase activity in Arabidopsis". We identify CAIR1, a UVR8-interacting protein, as a redox-responsive regulator of catalase localization and activity, maintaining cellular ROS balance. 🌱 www.biorxiv.org/content/10.6...

Our new year starts of course with new preprint on brassinosteroid signaling tinyurl.com/nhzcfkxd. We re-analyzed the function of Kelch phosphatases, which were previously characterized as protein tyrosine phosphatases that dephosphorylate the critical pTyr200 in the GSK3 kinase BIN2. (1/6)

Our latest collaboration with Fiedler lab @fmp-berlin.de and Panse labs UZH out on @biorxiv-plants.bsky.social. Using bead-adsorbed, non-hydrolyzable inositol pyrophosphate (PP-InsP) analogs, we isolated many putative PP-InsP-binding proteins from Arabidopsis. www.biorxiv.org/content/10.1... (1/6)

It’s finally out! 🎉 Work led by former PhD student @wei-xiao-botany.bsky.social , in collaboration with @bayerlab.bsky.social and @bertderybel.bsky.social AINTEGUMENTA phospho-switch regulates bilateral stem cell activity during secondary growth. 🔗 www.pnas.org/doi/10.1073/... #PlantSciences

Happy to share our latest manuscript about Brassinosteroid recognition 😎 hope it offers a broad and intensive understanding of BR ligands--BRI1-LIKE receptors mechanism.

Our latest on brassinosteroid signaling: Ligand binding spectrum, specificity & selectivity of all BR receptors in Arabidopsis. By @albertocaregnato.bsky.social , @hmchen93.bsky.social and our great chemistry collaborators Mirek Kvasnica, Jana Oklestkova and Mirek Strnad.

Nice analysis of ITPK and VIH inositol pyrophophate kinase over-expression lines in Arabidopsis. onlinelibrary.wiley.com/doi/10.1111/...

Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges #AlphaFold3, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism. www.biorxiv.org/content/10.1...

New Online! Mechanisms of auxin action in plant growth and development

novel and in-depth work 👍🏻

New Article: "Structural mechanism underlying PHO1;H1-mediated phosphate transport in Arabidopsis" rdcu.be/d62pA Phosphate transporter PHO1: cryo-EM, biochemical & physiological analysis. Molecular and regulatory mechanism of transport mediated by the SPX–EXS family. #PlantScience

BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10 https://www.biorxiv.org/content/10.1101/2024.11.26.625463v1

Perspectives on a co-option of a familiar signaling pathway for embryo patterning, where phosphorylation of SCREAM by MPK3/6 triggers different outcomes. But..Symmetric Cell Division is EXCITING and essential for generating a mirror-symmetric Guard Cell pair😘🌱. www.nature.com/articles/s41...

Super excited to announce that our SCRM story is officially published!!! 🎉🎉🎉 Want to discover the exciting new functions of ICE1/SCRM? Want to dive into the latest model of plant embryo initiation? Don’t miss out—check it out here: nph.onlinelibrary.wiley.com/doi/10.1111/...