Ivana Bukvin

Ivana Bukvin

@ivanabukvin.bsky.social

Incoming Group Leader at @mrclmb.bsky.social. Interested in how proteins fold. All opinions my own.

129 followers222 following3 posts

Ivana Bukvin reposted

Gabi Heller
@g-heller.bsky.social

Our mission is to make intrinsically disordered proteins (IDPs) druggable for everyone. Our first tool, SpinForecast, developed by @bindresearch.org with @ucl.ac.uk, takes a step towards that goal by dramatically speeding up #NMR assignments for IDPs. 🍝🧲🖥️

Bind Research@bindresearch.org

Check out the first tool from Bind Research: SpinForecast. #NMR is one of the most powerful tools for probing the atomic behaviour of IDPs. But the data can look like a Jackson Pollock painting: a sea of peaks that we must painstakingly match to positions along the protein backbone.

Ivana Bukvin
@ivanabukvin.bsky.social

A PhD project is available in my new lab to explore how proteins fold in real time as they are synthesised by the ribosome. Feel free to reach out!

MRC Laboratory of Molecular Biology@mrclmb.ac.uk

Ready to take the next step in your research career? The LMB is now accepting applications for PhD placements starting in October 2027. Deadline: 08 December 2026 (allow time for reference submission). Discover what we offer here: https://mrclmb.ac.uk/careers-and-people/phd-students/

Ivana Bukvin reposted

Joe Greener
@jgreener64.bsky.social

Now out as a perspective in PLOS Biology. Where next for structural bioinformatics? journals.plos.org/plosbiology/...

journals.plos.orgWhere next for structural bioinformatics?Structural bioinformatics aims to answer biological questions by considering biomolecular structures at scale. This Perspective argues that now that we have accurate predictions, we need to ask what w...
Joe Greener@jgreener64.bsky.social

I wrote a blog post about the future of structural bioinformatics. Where to go after AlphaFold? How do we avoid the field becoming a load of half-baked LLMs? Let me know what you think. jgreener64.github.io/posts/struct...

jgreener64.github.ioWhere next for structural bioinformatics?
Ivana Bukvin
@ivanabukvin.bsky.social

Very happy to share a new preprint characterising the unfolded state of a folding-competent domain at the cusp of folding initiation on the ribosome. Co-led by @julianstreit.bsky.social from my PhD in John Christodoulou's lab. Many thanks to all the co-authors!

biorxiv.orgThe initiation of de novo protein folding on the ribosomeHow the earliest structure within the unfolded state is formed during biosynthesis on the ribosome and whether it has any consequences for downstream folding remain open questions. Here, we combine 15...

Ivana Bukvin reposted

Nature Structural & Molecular Biology
@natsmb.nature.com

New online: Structures of protein folding intermediates on the ribosome

dlvr.itStructures of protein folding intermediates on the ribosomeNature Structural & Molecular Biology, Published online: 16 June 2026; doi:10.1038/s41594-026-01814-7Atomistic structural ensembles of protein folding intermediates on the ribosome are resolved by comprehensive 19F nuclear magnetic resonance analyses integrated with molecular dynamics simulations, providing insights into cotranslational folding pathways.

Ivana Bukvin reposted

Julian Streit
@julianstreit.bsky.social

Excited to share our work describing structural ensembles of protein folding intermediates on the ribosome is now published in @natsmb.nature.com ! www.nature.com/articles/s41... Very grateful to co-first author @sammyhschan.bsky.social, our supervisor John Christodoulou and all our co-authors.

nature.comStructures of protein folding intermediates on the ribosome - Nature Structural & Molecular BiologyAtomistic structural ensembles of protein folding intermediates on the ribosome are resolved by comprehensive 19F nuclear magnetic resonance analyses integrated with molecular dynamics simulations, pr...
Ivana Bukvin
@ivanabukvin.bsky.social

A bit of news! 😊 I'm delighted to be starting my lab @mrclmb.ac.uk. Protein folding remains one of the most profound puzzles in biology, and we'll be exploring how translation kinetics, the ribosome and chaperones shape this fundamental process. 🧩 Opportunities to join the group coming soon!

MRC Laboratory of Molecular Biology@mrclmb.ac.uk

The LMB is thrilled to announce the appointment of @ivanabukvin.bsky.social as a Group Leader in the PNAC Division. Beginning in January 2027, Ivana’s group will investigate co-translational folding and misfolding of proteins. Read more: mrclmb.ac.uk/news-events/...

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