James Nathan

✨Excited to share our latest paper in Aging Cell!✨ "Direct Pharmacological Activation of AMPK Extends Lifespan in Yeast, Worms and Flies" Thanks to all the collaborators who made this multi-organism study possible! 💊🪱🪰🐁⏳ #TeamScience #Drosophila #C.elegans #S.pombe #Ageing doi.org/10.1111/acel...

Secure your place at Redox – The Good, The Bad and The Unexpected by the super earlybird deadline of 16 August to save £100! Featuring an international lineup of redox experts, a publishing panel, networking opportunities and more, browse the exciting programme so far 🧪 bit.ly/Redox-26

Secure your place at Redox – The Good, The Bad and The Unexpected by the super earlybird deadline of 16 August to save £100! Featuring an international lineup of redox experts, a publishing panel, networking opportunities and more, browse the exciting programme so far 🧪 bit.ly/Redox-26

🔬 Respiratory Mechanisms of Disease (RC49887) Join @jamesnathanlab.bsky.social at #CITIID & @mitogene.bsky.social @mrc-mbu.bsky.social to investigate how mitochondrial dysfunction and mtDNA damage drive innate immune activation and contribute to COPD. 📅 Closing date: 5 July 2026 🔗 buff.ly/ujQDD8l

📍 Registration is now open for this #Redox #BiochemicalSociety Meeting! Excellent invited speakers, plus many slots for elevated talks from abstracts, including #ECRs 🫵 🌍 Cambridge, UK 🗓️ 16-18 Nov 2026 ⏳ Super early bird deadline: 16 Aug 2026 🌐 bit.ly/Redox-26 #BiochemEvent @biochemsoc.bsky.social

Congratulations Qing and Team on this exciting work www.jci.org/articles/vie...

Delighted to share the 'early access' version of our work examining genetic dependencies with VHL loss in ccRCC. Led by James Bertlin. Thanks to our wonderful collaborators Qing Zhang, Annie Speak, Tom Mitchell. Presenting the work today at #AACRkidney26 www.nature.com/articles/s41...

VHL synthetic lethality screens uncover CBF-β as a negative regulator of STING @natcomms.nature.com www.nature.com/articles/s41...

Congratulations Manu, Sarah and Team! Enjoyed contributing to this work www.nature.com/articles/s41...

Excited to share our first bioinformatics contribution! 🎉 Led by Niek Wit in collaboration with the van den Ameele lab @jellevda.bsky.social , we developed DamMapper damid-seq.readthedocs.io/en/latest/, a workflow for DamID-seq analysis, to map SET1B and HIF-1 chromatin occupancy. rdcu.be/eK2TS

Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...

Congrats to #ListerFellow @jamesnathanlab.bsky.social and team on this tremendous paper in Science Advances exploring iron flux and metabolism. "Potentially explaining how some tumors evade antitumoral immunity."

Happy to share latest work from the lab. Led by talented first author @awmartinelli.bsky.social. Mapping the genetic landscape of iron metabolism uncovers the SETD2 methyltransferase as a modulator of iron flux | Science Advances www.science.org/doi/10.1126/... Congratulations to all the team.

"The Lister... spans an incredible breadth of science, giving access to world-leading experts in fields far from my own." @jamesnathanlab.bsky.social James and other #ListerFellows reflect on surprise discoveries and following their curiosity. #ListerPrize 👉 lister-institute.org.uk/curiosity-at...

🧬 New in @natchembio.nature.com : Researchers at #CITIID @cam.ac.uk & @ki.se identified #ABHD11 – a key enzyme that controls cellular energy production & immune response. Learn more: buff.ly/ZdOAdLe @hudsonwilco.bsky.social @jamesnathanlab.bsky.social

Delighted to share our latest work on ABHD11 as a novel deglutarylating enzyme, and its role in T cell metabolism @natchembio.nature.com rdcu.be/ewiYZ. Many congratulations to co-first authors Guine Grice, Eleanor Minogue and @hudsonwilco.bsky.social! Great team effort with Randall Johnson's lab.

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis www.nature.com/articles/s41...

🚨 New paper alert! 🚨 Check out our latest work on HypoxyStat, a small-molecule therapy that increases oxygen-hemoglobin affinity and provides a practical form of hypoxia therapy. A great collaboration with Maze Therapeutics 🔗 Paper: doi.org/10.1016/j.ce... @cp-cell.bsky.social

People working on #cancermetabolism, #mitochondrialbiology, #metabolism, please reach out! Share this so I can follow who is here! I will share paper on cancer metabolism, but anything else related to mitochondria and metabolism.